Cross-antagonism of a T cell clone expressing two distinct T cell receptors.
暂无分享,去创建一个
C. Janeway | R. Germain | C A Janeway | B. Dittel | B N Dittel | R N Germain | I Stefanova | I. Štefanov́a | IrenaŠtefanova
[1] T. McKeithan,et al. Kinetic proofreading in T-cell receptor signal transduction. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[2] K. Siminovitch,et al. Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase , 1996, The Journal of experimental medicine.
[3] C. Walsh,et al. Phosphorylation of Ser-42 and Ser-59 in the N-terminal region of the tyrosine kinase p56lck. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[4] H. Ploegh,et al. Peptide antagonism and T cell receptor interactions with peptide-MHC complexes. , 1998, Immunity.
[5] Mark M. Davis,et al. Ligand-specific oligomerization of T-cell receptor molecules , 1997, Nature.
[6] H. Grey,et al. Antigen analogs as tools to study T-cell activation function and activation. , 1996, Seminars in immunology.
[7] Lars Fugger,et al. Quantitative Analysis of Peptides from Myelin Basic Protein Binding to the MHC Class II Protein, I-Au, Which Confers Susceptibility to Experimental Allergic Encephalomyelitis , 1996, Molecular medicine.
[8] A. Lanzavecchia,et al. A T cell receptor (TCR) antagonist competitively inhibits serial TCR triggering by low‐affinity ligands, but does not affect triggering by high‐affinity anti‐CD3 antibodies , 1997, European journal of immunology.
[9] C. Janeway,et al. Ligands for the T-cell receptor: hard times for avidity models. , 1995, Immunology today.
[10] Dan R. Littman,et al. Signal transduction by lymphocyte antigen receptors , 1994, Cell.
[11] C. Janeway,et al. Peptide antagonists inhibit proliferation and the production of IL-4 and/or IFN-gamma in T helper 1, T helper 2, and T helper 0 clones bearing the same TCR. , 1997, Journal of immunology.
[12] Antonio Lanzavecchia,et al. T Cell Activation Determined by T Cell Receptor Number and Tunable Thresholds , 1996, Science.
[13] C. Janeway,et al. Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells , 1983, The Journal of experimental medicine.
[14] R. Germain,et al. Relationships among TCR ligand potency, thresholds for effector function elicitation, and the quality of early signaling events in human T cells. , 1998, Journal of immunology.
[15] Paul M. Allen,et al. Partial T cell signaling: Altered phospho-ζ and lack of zap70 recruitment in APL-induced T cell anergy , 1994, Cell.
[16] R. Germain,et al. Peptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signaling , 1993, The Journal of experimental medicine.
[17] J. Altman,et al. Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands [corrected]. , 1998, Immunity.
[18] D. Fremont,et al. High- and low-potency ligands with similar affinities for the TCR: the importance of kinetics in TCR signaling. , 1998, Immunity.
[19] B. Malissen,et al. Each of the two productive T cell receptor α-gene rearrangements found in both the A10 and BM 3.3 T cell clones give rise to an α chain which can contribute to the constitution of a surface-expressed αβ dimer , 1991 .
[20] G. Crabtree,et al. Signal transmission between the plasma membrane and nucleus of T lymphocytes. , 1994, Annual review of biochemistry.
[21] R. Germain,et al. Marked differences in the efficiency of expression of distinct alpha beta T cell receptor heterodimers. , 1989, Journal of immunology.
[22] P. Allen,et al. Fidelity of T cell activation through multistep T cell receptor zeta phosphorylation. , 1998, Science.
[23] D. Wraith,et al. An autoantigenic T cell epitope forms unstable complexes with class II MHC: a novel route for escape from tolerance induction. , 1993, International immunology.
[24] C. Janeway,et al. Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma , 1993, The Journal of experimental medicine.
[25] R. Germain,et al. Partial signaling by CD8+ T cells in response to antagonist ligands , 1996, The Journal of experimental medicine.
[26] E. Palmer,et al. T Cell Receptor (TCR) Antagonism without a Negative Signal: Evidence from T Cell Hybridomas Expressing Two Independent TCRs , 1999, The Journal of experimental medicine.
[27] H. Metzger,et al. An unusual mechanism for ligand antagonism. , 1998, Science.
[28] H. Grey,et al. Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor , 1992, Cell.
[29] M. Davis,et al. Kinetic discrimination in T-cell activation. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[30] Y. Chien,et al. A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists. , 1996, Immunity.
[31] C. Janeway,et al. T cells with two functional antigen-specific receptors. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[32] R. Germain,et al. The Efficiency of CD4 Recruitment to Ligand-engaged TCR Controls the Agonist/Partial Agonist Properties of Peptide–MHC Molecule Ligands , 1997, The Journal of experimental medicine.
[33] S. Jameson,et al. T-cell-receptor affinity and thymocyte positive selection , 1996, Nature.
[34] O. Acuto,et al. Syk and ZAP-70 mediate recruitment of p56lck/CD4 to the activated T cell receptor/CD3/zeta complex , 1995, The Journal of experimental medicine.
[35] L. Wahl,et al. Lipopolysaccharide induces activation of CD14-associated protein tyrosine kinase p53/56lyn. , 1993, The Journal of biological chemistry.
[36] P. Allen,et al. Cutting edge: the tyrosine phosphatase SHP-1 regulates thymocyte positive selection. , 1999, Journal of immunology.
[37] J. Fargnoli,et al. Temporal regulation of non-transmembrane protein tyrosine kinase enzyme activity following T cell antigen receptor engagement. , 1994, The Journal of biological chemistry.
[38] S. Jameson,et al. Cutting edge: a test of the dominant negative signal model for TCR antagonism. , 1999, Journal of immunology.
[39] A. Lanzavecchia,et al. Serial triggering of many T-cell receptors by a few peptideMHC complexes , 1995, Nature.
[40] C. Walsh,et al. Lck-dependent tyrosyl phosphorylation of the phosphotyrosine phosphatase SH-PTP1 in murine T cells , 1994, Molecular and cellular biology.
[41] M. Bevan,et al. T cell receptor antagonists and partial agonists. , 1995, Immunity.
[42] Arthur Weiss,et al. Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor , 1992, Cell.
[43] Arthur Weiss,et al. ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR ζ chain , 1992, Cell.
[44] R. Germain,et al. Single Cell Analysis Reveals Regulated Hierarchical T Cell Antigen Receptor Signaling Thresholds and Intraclonal Heterogeneity for Individual Cytokine Responses of CD4+ T Cells , 1997, The Journal of experimental medicine.
[45] P. Allen,et al. Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology. , 1996, Annual review of immunology.
[46] H. Grey,et al. Differential T cell signaling induced by antagonist peptide-MHC complexes and the associated phenotypic responses. , 1997, Journal of immunology.
[47] L. Samelson,et al. Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists , 1995, Science.
[48] D. Plas,et al. Direct Regulation of ZAP-70 by SHP-1 in T Cell Antigen Receptor Signaling , 1996, Science.
[49] A. Lanzavecchia,et al. The duration of antigenic stimulation determines the fate of naive and effector T cells. , 1998, Immunity.