A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

[1]  J. Downward,et al.  Activation of phosphoinositide 3‐kinase by interaction with Ras and by point mutation. , 1996, The EMBO journal.

[2]  C. Kenyon,et al.  The age-1 and daf-2 genes function in a common pathway to control the lifespan of Caenorhabditis elegans. , 1995, Genetics.

[3]  T. Hunter,et al.  When is a lipid kinase not a lipid kinase? When it is a protein kinase , 1995, Cell.

[4]  B. Burgering,et al.  Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction , 1995, Nature.

[5]  S. Volinia,et al.  Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase. , 1995, Science.

[6]  M. White,et al.  The structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinase , 1995, Molecular and cellular biology.

[7]  Andrius Kazlauskas,et al.  The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase , 1995, Cell.

[8]  D. Riddle,et al.  Genes that regulate both development and longevity in Caenorhabditis elegans. , 1995, Genetics.

[9]  G. Cooper,et al.  Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor. , 1995, Science.

[10]  Simeon I. Taylor,et al.  Insulin-induced activation of a phosphatidyl inositol 3-kinase. Demonstration that the P85 subunit binds directly to the COOH terminus of the insulin receptor in intact cells , 2022 .

[11]  M. Ikeda,et al.  Neurosecretory cells expressing the gene for common precursor for diapause hormone and pheromone biosynthesis-activating neuropeptide in the suboesophageal ganglion of the silkworm, Bombyx mori. , 1994, General and comparative endocrinology.

[12]  L. Cantley,et al.  Phosphatidylinositol 3‐kinase , 1994, BioEssays : news and reviews in molecular, cellular and developmental biology.

[13]  K. Onodera,et al.  Neurite outgrowth of PC12 cells is suppressed by wortmannin, a specific inhibitor of phosphatidylinositol 3-kinase. , 1994, The Journal of biological chemistry.

[14]  M. Thelen,et al.  Wortmannin binds specifically to 1-phosphatidylinositol 3-kinase while inhibiting guanine nucleotide-binding protein-coupled receptor signaling in neutrophil leukocytes. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[15]  G. Ruvkun,et al.  daf-2, daf-16 and daf-23: genetically interacting genes controlling Dauer formation in Caenorhabditis elegans. , 1994, Genetics.

[16]  T. Okada,et al.  Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase. , 1994, The Journal of biological chemistry.

[17]  M. Kasuga,et al.  PI 3‐kinase: structural and functional analysis of intersubunit interactions. , 1994, The EMBO journal.

[18]  Y. Nonomura,et al.  Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells. , 1993, The Journal of biological chemistry.

[19]  C. Kenyon,et al.  A C. elegans mutant that lives twice as long as wild type , 1993, Nature.

[20]  P. L. Larsen.  Aging and resistance to oxidative damage in Caenorhabditis elegans. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[21]  J. Thomas,et al.  Evidence for parallel processing of sensory information controlling dauer formation in Caenorhabditis elegans. , 1993, Genetics.

[22]  J. Vanfleteren.  Oxidative stress and ageing in Caenorhabditis elegans. , 1993, The Biochemical journal.

[23]  L. Cantley,et al.  A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity , 1993, Molecular and cellular biology.

[24]  R. Staden,et al.  The C. elegans genome sequencing project: a beginning , 1992, Nature.

[25]  J. Thomas,et al.  Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans. , 1992, Genetics.

[26]  Caleb E. Finch,et al.  Longevity, senescence, and the genome , 1990 .

[27]  T. Johnson,et al.  A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility. , 2002, Genetics.

[28]  M. Klass.  A method for the isolation of longevity mutants in the nematode Caenorhabditis elegans and initial results , 1983, Mechanisms of Ageing and Development.

[29]  D. Riddle,et al.  Interacting genes in nematode dauer larva formation , 1981, Nature.