Therapeutic Effects of Rapamycin on MPTP-Induced Parkinsonism in Mice
暂无分享,去创建一个
[1] E. Katunina,et al. [Epidemiology of Parkinson's disease]. , 2013, Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova.
[2] A. Schober,et al. Nucleolar Disruption in Dopaminergic Neurons Leads to Oxidative Damage and Parkinsonism through Repression of Mammalian Target of Rapamycin Signaling , 2011, The Journal of Neuroscience.
[3] Lloyd A Greene,et al. Rapamycin Protects against Neuron Death in In Vitro andIn Vivo Models of Parkinson's Disease , 2010, The Journal of Neuroscience.
[4] D. Klionsky,et al. Regulation mechanisms and signaling pathways of autophagy. , 2009, Annual review of genetics.
[5] L. Greene,et al. RTP801 Is Induced in Parkinson's Disease and Mediates Neuron Death by Inhibiting Akt Phosphorylation/Activation , 2008, The Journal of Neuroscience.
[6] Chun-Feng Liu,et al. Autophagic pathway and probable mechanism in degradation of mutant α-synuclein in PC12 cells , 2008 .
[7] G. Rigatelli,et al. Patent foramen ovale management: who should do what? , 2007, European journal of neurology.
[8] D. Rubinsztein,et al. Trehalose, a Novel mTOR-independent Autophagy Enhancer, Accelerates the Clearance of Mutant Huntingtin and α-Synuclein* , 2007, Journal of Biological Chemistry.
[9] D. Rubinsztein,et al. The roles of intracellular protein-degradation pathways in neurodegeneration , 2006, Nature.
[10] M. Breteler,et al. Epidemiology of Parkinson's disease , 2006, The Lancet Neurology.
[11] D. Rubinsztein,et al. Rapamycin pre-treatment protects against apoptosis. , 2006, Human molecular genetics.
[12] Andrew B West,et al. Molecular pathophysiology of Parkinson's disease. , 2005, Annual review of neuroscience.
[13] I. Germano,et al. Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3 , 2005, Oncogene.
[14] Craig B. Thompson,et al. Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes , 2004, Nature Cell Biology.
[15] Ajjai Alva,et al. Regulation of an ATG7-beclin 1 Program of Autophagic Cell Death by Caspase-8 , 2004, Science.
[16] E. Masliah,et al. Enhanced substantia nigra mitochondrial pathology in human α-synuclein transgenic mice after treatment with MPTP 1 1 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine. , 2004, Experimental Neurology.
[17] Daniel J Klionsky,et al. Development by self-digestion: molecular mechanisms and biological functions of autophagy. , 2004, Developmental cell.
[18] L. Petrucelli,et al. Mechanism of neurodegenerative disease: role of the ubiquitin proteasome system , 2004, Annals of medicine.
[19] Jeremy N. Skepper,et al. α-Synuclein Is Degraded by Both Autophagy and the Proteasome* , 2003, Journal of Biological Chemistry.
[20] E. Masliah,et al. α-Synuclein is phosphorylated in synucleinopathy lesions , 2002, Nature Cell Biology.
[21] E. Masliah,et al. alpha-Synuclein is phosphorylated in synucleinopathy lesions. , 2002, Nature cell biology.
[22] L. Greene,et al. Expression of A53T Mutant But Not Wild-Type α-Synuclein in PC12 Cells Induces Alterations of the Ubiquitin-Dependent Degradation System, Loss of Dopamine Release, and Autophagic Cell Death , 2001, The Journal of Neuroscience.
[23] L. Chan,et al. Evolution of immunosuppression and continued importance of acute rejection in renal transplantation. , 2001, American journal of kidney diseases : the official journal of the National Kidney Foundation.
[24] S. Emr,et al. Autophagy as a regulated pathway of cellular degradation. , 2000, Science.
[25] D. Klionsky,et al. Dissection of Autophagosome Biogenesis into Distinct Nucleation and Expansion Steps , 2000, The Journal of cell biology.
[26] J. Trojanowski,et al. Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions. , 2000, Science.
[27] Kazuya Nagano,et al. Tor-Mediated Induction of Autophagy via an Apg1 Protein Kinase Complex , 2000, The Journal of cell biology.
[28] E. Masliah,et al. α-Synuclein Promotes Mitochondrial Deficit and Oxidative Stress , 2000 .
[29] A. Hackam,et al. Inhibiting Caspase Cleavage of Huntingtin Reduces Toxicity and Aggregate Formation in Neuronal and Nonneuronal Cells* , 2000, The Journal of Biological Chemistry.
[30] E. Masliah,et al. alpha-synuclein promotes mitochondrial deficit and oxidative stress. , 2000, The American journal of pathology.
[31] D. Klionsky,et al. Vacuolar import of proteins and organelles from the cytoplasm. , 1999, Annual review of cell and developmental biology.
[32] N. Mizushima,et al. A New Protein Conjugation System in Human , 1998, The Journal of Biological Chemistry.
[33] T. Gotow,et al. An ultrastructural and immunohistochemical study of PC12 cells during apoptosis induced by serum deprivation with special reference to autophagy and lysosomal cathepsins. , 1998, Archives of histology and cytology.
[34] M. Polymeropoulos. Autosomal dominant parkinson's disease and α‐synuclein , 1998 .
[35] M. Polymeropoulos. Autosomal dominant Parkinson's disease and alpha-synuclein. , 1998, Annals of neurology.
[36] R. Krüger,et al. Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. , 1998, Nature genetics.
[37] Y. Agid,et al. Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease. , 1997, Histology and histopathology.
[38] M G Spillantini,et al. Alpha-synuclein in Lewy bodies. , 1997, Nature.