Extreme ultraviolet (EUV) surface modification of polytetrafluoroethylene (PTFE) for control of biocompatibility

Extreme ultraviolet (EUV) surface modification of polytetrafluoroethylene (PTFE) was performed in order to enhance the degree of biocompatibility. Polymer samples were irradiated by different number of EUV shots using a laser–plasma based EUV source in the presence of nitrogen gas. The physical and chemical properties of EUV modified PTFE samples were studied using Atomic Force Microscopy, X-ray photoelectron spectroscopy and water contact angle (WCA) methods. Pronounced wall type micro and nano-structures appeared on the EUV treated polymer surfaces resulting in increased surface roughness and hydrophobicity. Stronger cell adhesion and good cell morphology were observed on EUV modified surfaces by in-vitro cell culture studies performed using L929 fibroblasts.

[1]  Andrzej Bartnik,et al.  EUV-induced physico-chemical changes in near-surface layers of polymers , 2011 .

[2]  Matthias Gabriel,et al.  Wet-chemical approach for the cell-adhesive modification of polytetrafluoroethylene , 2011, Biomedical materials.

[3]  T. Takahagi,et al.  XPS study of an ion sputtering process of fluoropolymers using Monte Carlo simulation , 1987 .

[4]  Philip J. Martin,et al.  The properties of fluorine containing diamond-like carbon films prepared by plasma-enhanced chemical vapour deposition , 2009 .

[5]  H. Nygren,et al.  Different kinetics of the respiratory burst response in granulocytes, induced by serum from blood coagulated in contact with polymer materials. , 2000, Biomaterials.

[6]  J. Jagur-grodzinski Biomedical application of functional polymers , 1999 .

[7]  Andrzej Bartnik,et al.  Surface modification of polymers for biocompatibility via exposure to extreme ultraviolet radiation. , 2014, Journal of biomedical materials research. Part A.

[8]  D. Attwood Soft X-Rays and Extreme Ultraviolet Radiation , 1999 .

[9]  U Klinge,et al.  PVDF as a new polymer for the construction of surgical meshes. , 2002, Biomaterials.

[10]  H. Busscher,et al.  Thermodynamic aspects of cell spreading on solid substrata , 1988, Cell Biophysics.

[11]  H. Wabnitz,et al.  Damage to VUV, EUV, and X-ray Optics III , 2011 .

[12]  A. Bartnik,et al.  Physical and chemical modifications of PET surface using a laser-plasma EUV source , 2010 .

[13]  J. Byrne,et al.  Evaluation of glycine adsorption on diamond like carbon (DLC) and fluorinated DLC deposited by plasma-enhanced chemical vapour deposition (PECVD) , 2012 .

[14]  Libor Juha,et al.  Micromachining of organic polymers by X-ray photo-etching using a 10Hz laser-plasma radiation source , 2005 .

[15]  J. Feijen,et al.  Interaction of cultured human endothelial cells with polymeric surfaces of different wettabilities. , 1985, Biomaterials.

[16]  Andrzej Bartnik,et al.  Laser-plasma EUV source dedicated for surface processing of polymers , 2011 .

[17]  Yihe Zhang,et al.  Plasma surface modification of poly vinyl chloride for improvement of antibacterial properties. , 2006, Biomaterials.

[18]  J. Heitz,et al.  Cell adhesion on polytetrafluoroethylene modified by UV-irradiation in an ammonia atmosphere. , 2003, Journal of biomedical materials research. Part A.

[19]  Andrew G. Glen,et al.  APPL , 2001 .

[20]  Kim Carneiro,et al.  The scanning tunneling microscope and surface characterization , 1993 .

[21]  Waldemar Mróz,et al.  Laser induced surface modification of polylactide , 2012 .

[22]  Randall L. Headrick,et al.  Self-assembled and etched cones on laser ablated polymer surfaces , 2006 .

[23]  Andrzej Bartnik,et al.  Simultaneous treatment of polymer surface by EUV radiation and ionized nitrogen , 2012 .

[24]  Benjamin G Keselowsky,et al.  Surface chemistry modulates focal adhesion composition and signaling through changes in integrin binding. , 2004, Biomaterials.

[25]  K. Jandt,et al.  Tuning Cell Adhesion on PTFE Surfaces by Laser Induced Microstructures , 2007 .

[26]  F. Cui,et al.  A review of investigations on biocompatibility of diamond-like carbon and carbon nitride films , 2000 .

[27]  L. Peña,et al.  Cell attachment and biocompatibility of polytetrafluoroethylene (PTFE) treated with glow-discharge plasma of mixed ammonia and oxygen , 2003, Journal of biomaterials science. Polymer edition.

[28]  Buddy D. Ratner,et al.  Biomaterials Science: An Introduction to Materials in Medicine , 1996 .

[29]  Vaclav Svorcik,et al.  Modulation of cell adhesion, proliferation and differentiation on materials designed for body implants. , 2011, Biotechnology advances.

[30]  L. Bačáková,et al.  Molecular mechanisms of improved adhesion and growth of an endothelial cell line cultured on polystyrene implanted with fluorine ions. , 2000, Biomaterials.

[31]  J. Heitz,et al.  Adhesion and proliferation of human vascular cells on UV‐light‐modified polymers , 2004, Biotechnology and applied biochemistry.

[32]  Liang Guo,et al.  A lithographically-patterned, elastic multi-electrode array for surface stimulation of the spinal cord , 2008, Biomedical microdevices.

[33]  Gavin Jell,et al.  Biofunctionalization of biomaterials for accelerated in situ endothelialization: a review. , 2008, Biomacromolecules.

[34]  Elena P Ivanova,et al.  Plasma-assisted surface modification of organic biopolymers to prevent bacterial attachment. , 2011, Acta biomaterialia.

[35]  F. Leisch,et al.  Adhesion and proliferation of human endothelial cells on photochemically modified polytetrafluoroethylene. , 2003, Biomaterials.

[36]  K. Schröder,et al.  Plasma-induced chemical micropatterning for cell culturing applications: a brief review , 1999 .

[37]  J. Fluitman,et al.  A survey on the reactive ion etching of silicon in microtechnology , 1996 .

[38]  J. Koenderink Q… , 2014, Les noms officiels des communes de Wallonie, de Bruxelles-Capitale et de la communaute germanophone.

[39]  F. Reniers,et al.  XPS and contact angle study of N2 and O2 plasma‐modified PTFE, PVDF and PVF surfaces , 2006 .

[40]  Meng‐Jiy Wang,et al.  Modulation of biocompatibility on poly(vinylidene fluoride) and polysulfone by oxygen plasma treatment and dopamine coating. , 2012, Journal of biomedical materials research. Part A.

[41]  A. Bartnik,et al.  EUV micropatterning for biocompatibility control of PET , 2010 .

[42]  Libor Juha,et al.  Strong temperature effect on X-ray photo-etching of polytetrafluoroethylene using a 10 Hz laser-plasma radiation source based on a gas puff target , 2006 .

[43]  W. Świȩszkowski,et al.  Biological characterization of woven fabric using two- and three-dimensional cell cultures. , 2012, Journal of biomedical materials research. Part A.