Intestinal aspartate proteases TiCatD and TiCatD2 of the haematophagous bug Triatoma infestans (Reduviidae): sequence characterisation, expression pattern and characterisation of proteolytic activity.

[1]  Eloi S. Garcia,et al.  Interactions between intestinal compounds of triatomines and Trypanosoma cruzi. , 2010, Trends in parasitology.

[2]  Eva C. Winnebeck,et al.  Why Does Insect RNA Look Degraded? , 2010, Journal of insect science.

[3]  B. Warscheid,et al.  A salivary serine protease of the haematophagous reduviid Panstrongylus megistus: sequence characterization, expression pattern and characterization of proteolytic activity , 2010, Insect molecular biology.

[4]  W. Terra,et al.  Sequence and function of lysosomal and digestive cathepsin D-like proteinases of Musca domestica midgut. , 2009, Insect biochemistry and molecular biology.

[5]  K. Zhu‐Salzman,et al.  CmCatD, a cathepsin D-like protease has a potential role in insect defense against a phytocystatin. , 2009, Journal of insect physiology.

[6]  R. Araujo,et al.  The Role of Salivary and Intestinal Complement System Inhibitors in the Midgut Protection of Triatomines and Mosquitoes , 2009, PloS one.

[7]  C. Caffrey,et al.  Parasites & Vectors BioMed Central , 2008 .

[8]  J. Andersen,et al.  An insight into the sialome of the blood-sucking bug Triatoma infestans, a vector of Chagas' disease. , 2008, Insect biochemistry and molecular biology.

[9]  M. Nei,et al.  MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. , 2007, Molecular biology and evolution.

[10]  Bo Yeon Kim,et al.  Functional role of aspartic proteinase cathepsin D in insect metamorphosis , 2006, BMC Developmental Biology.

[11]  P. Azambuja,et al.  Trypanosoma cruzi: effects of infection on cathepsin D activity in the midgut of Rhodnius prolixus. , 2006, Experimental parasitology.

[12]  C. Mayer,et al.  Serine proteinases of the human body louse (Pediculus humanus): sequence characterization and expression patterns , 2005, Parasitology Research.

[13]  W. Terra,et al.  The cathepsin L-like proteinases from the midgut of Tenebrio molitor larvae: sequence, properties, immunocytochemical localization and function. , 2005, Insect biochemistry and molecular biology.

[14]  W. Schuhmann,et al.  Fabrication of a potentiometric/amperometric bifunctional enzyme microbiosensor. , 2005, Analytical chemistry.

[15]  P. Billingsley,et al.  Activity and sequence characterization of two cysteine proteases in the digestive tract of the reduviid bug Triatoma infestans , 2004, Insect molecular biology.

[16]  V. Turk,et al.  Novel aspartyl proteinase associated to fat body histolysis during Ceratitis capitata early metamorphosis. , 2004, Archives of insect biochemistry and physiology.

[17]  Kai A. Reidegeld,et al.  Towards data management of the HUPO Human Brain Proteome Project pilot phase , 2004, Proteomics.

[18]  S. Brunak,et al.  Improved prediction of signal peptides: SignalP 3.0. , 2004, Journal of molecular biology.

[19]  Lin Hong,et al.  Flap position of free memapsin 2 (beta-secretase), a model for flap opening in aspartic protease catalysis. , 2004, Biochemistry.

[20]  Joachim Klose,et al.  Interpretation of mass spectrometry data for high-throughput proteomics , 2003, Analytical and bioanalytical chemistry.

[21]  A. Moorman,et al.  Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data , 2003, Neuroscience Letters.

[22]  B. Dunn Structure and mechanism of the pepsin-like family of aspartic peptidases. , 2002, Chemical reviews.

[23]  G. Horgan,et al.  Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR , 2002 .

[24]  M. Sajid,et al.  Cysteine proteases of parasitic organisms. , 2002, Molecular and biochemical parasitology.

[25]  T. López-Ordoñez,et al.  Characterization of a cDNA encoding a cathepsin L‐like protein of Rhodnius prolixus , 2001, Insect molecular biology.

[26]  L Hennig,et al.  WinPep 2.11: novel software for PC-based analyses of amino acid sequences. , 2001, Preparative biochemistry & biotechnology.

[27]  M. Pfaffl,et al.  A new mathematical model for relative quantification in real-time RT-PCR. , 2001, Nucleic acids research.

[28]  G. Schaub,et al.  The development of Trypanosoma cruzi in triatominae. , 2000, Parasitology today.

[29]  L. Bini,et al.  Aspartyl proteases in Caenorhabditis elegans. Isolation, identification and characterization by a combined use of affinity chromatography, two-dimensional gel electrophoresis, microsequencing and databank analysis. , 1999, European journal of biochemistry.

[30]  A. Raikhel,et al.  Mosquito Cathepsin B-like Protease Involved in Embryonic Degradation of Vitellin Is Produced as a Latent Extraovarian Precursor* , 1999, The Journal of Biological Chemistry.

[31]  G. Schaub,et al.  The Development of Trypanosoma cruzi (Trypanosomatidae) in the Reduviid Bug Triatoma infestans (Insecta): Influence of Starvation , 1998, The Journal of eukaryotic microbiology.

[32]  J. Thompson,et al.  The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. , 1997, Nucleic acids research.

[33]  M. Nishiyama,et al.  Involvement of a residue at position 75 in the catalytic mechanism of a fungal aspartic proteinase, Rhizomucor pusillus pepsin. Replacement of tyrosine 75 on the flap by asparagine enhances catalytic efficiency. , 1996, Protein engineering.

[34]  W. Terra,et al.  Insect digestive enzymes: properties, compartmentalization and function , 1994 .

[35]  W. Terra,et al.  Digestive and absorptive sites along the midgut of the cotton seed sucker bug Dysdercus peruvianus (Hemiptera: Pyrrhocoridae) , 1994 .

[36]  M. Lehane Digestive enzymes, haemolysins and symbionts in the search for vaccines against blood-sucking insects. , 1994, International journal for parasitology.

[37]  A. Raikhel,et al.  Cloning of cDNA for mosquito lysosomal aspartic protease. Sequence analysis of an insect lysosomal enzyme similar to cathepsins D and E. , 1992, The Journal of biological chemistry.

[38]  G. Conner Isolation of procathepsin D from mature cathepsin D by pepstatin affinity chromatography. Autocatalytic proteolysis of the zymogen form of the enzyme. , 1989, The Biochemical journal.

[39]  C. G. Vallejo,et al.  An aspartic proteinase in Drosophila: maternal origin and yolk localization. , 1989, The International journal of developmental biology.

[40]  G. Schaub Trypanosoma cruzi: quantitative studies of development of two strains in small intestine and rectum of the vector Triatoma infestans. , 1989, Experimental parasitology.

[41]  P. Billingsley,et al.  Changes in the Anterior Midgut Cells of Adult Female Rhodnius prolixus (Hemiptera: Reduviidae) after Feeding , 1989 .

[42]  P. Billingsley,et al.  Ultrastructural changes in posterior midgut cells associated with blood feeding in adult female Rhodnius prolixus Stal (Hemiptera: Reduviidae) , 1983 .

[43]  J. Houseman A thiol-activated digestive proteinase from adults of Rhodnius prolixus Stål (Hemiptera: Reduviidae) , 1978 .

[44]  K. Hori Physiological conditions in the midgut in relation to starch digestion and the salivary amylase of the bug Lygus disponsi , 1971 .

[45]  J. B. Ford,et al.  The distribution and localization of digestive enzymes in the alimentary canal and salivary glands of the cotton stainer, Dysdercus fasciatus , 1967 .

[46]  V. Dijl Handbook of Proteolytic Enzymes, third edition , 2013 .

[47]  G. Schaub Chapter 4 Interactions of Trypanosomatids and Triatomines , 2009 .

[48]  W. Schuhmann,et al.  Constant-Distance Mode Scanning Potentiometry. High Resolution pH Measurements in Three-Dimensions , 2007 .

[49]  M. James Catalytic pathway of aspartic peptidases , 2004 .

[50]  R D Appel,et al.  Protein identification and analysis tools in the ExPASy server. , 1999, Methods in molecular biology.

[51]  K. Nicholas,et al.  GeneDoc: Analysis and visualization of genetic variation , 1997 .

[52]  J. Baker,et al.  Compartmentalization of digestion , 1996 .

[53]  H. Neurath Proteolytic processing and regulation. , 1991, Enzyme.

[54]  A. Raikhel,et al.  Purification and characterization of a lysosomal aspartic protease with cathepsin D activity from the mosquito , 1991 .

[55]  M. Lehane Managing the blood meal , 1991 .

[56]  W. Terra Evolution of Digestive Systems of Insects , 1990 .

[57]  N. Thie,et al.  Identification of cathepsin B, D and H in the larval midgut of Colorado potato beetle, Leptinotarsa decemlineata Say (Coleoptera: Chrysomelidae). , 1990 .

[58]  D. Davies,et al.  Structure and Function of the Aspartic Proteinases , 1990, Advances in Experimental Medicine and Biology.

[59]  W. Terra,et al.  Origin, distribution, properties and functions of the major Rhodnius prolixus midgut hydrolases , 1988 .

[60]  W. Terra,et al.  Physiological adaptations for digesting bacteria. Water fluxes and distribution of digestive enzymes in Musca domestica larval midgut , 1987 .

[61]  A. Downe,et al.  Activity cycles and the control of four digestive proteinases in the posterior midgut of Rhodnius prolixus Stål (Hemiptera: Reduviidae) , 1983 .

[62]  J. A. Guimarães,et al.  Haemolytic factor from the crop of Rhodnius prolixus: Evidence and partial characterization , 1983 .

[63]  A. Downe,et al.  The effects of three metabolic inhibitors on digestive proteinase production in Rhodnius prolixus Stål (Hemiptera: Reduviidae) , 1983 .

[64]  A. Downe,et al.  Characterization of an acidic proteinase from the posterior midgut of Rhodnius prolixus stål (hemiptera: Reduviidae) , 1982 .

[65]  A. Downe,et al.  Identification and partial characterization of digestive proteinases from Triatoma phyllosoma pallidipennis stål (hemiptera: Reduviidae) , 1981 .

[66]  A. Downe,et al.  Endoproteinase activity in the posterior midgut of Rhodnius prolixus Stål (Hemiptera: Reduviidae) , 1980 .

[67]  M. L. García,et al.  Control of protease secretion in the intestine of fifth instar larvae of Rhodnius prolixus. , 1977, Journal of insect physiology.

[68]  H. Britton,et al.  CXCVIII.—Universal buffer solutions and the dissociation constant of veronal , 1931 .

[69]  Gapped BLAST and PSI-BLAST: A new , 1997 .