2-Hydroxylated fatty acids as candidates of novel drugs to promote chemosensitivity of gastric cancer

[1]  Wei Zhang,et al.  Fatty acid 2-hydroxylation inhibits tumor growth and increases sensitivity to cisplatin in gastric cancer , 2019, EBioMedicine.

[2]  Jin-bo Gao,et al.  Molecular mechanisms of chemoresistance in gastric cancer , 2016, World journal of gastrointestinal oncology.

[3]  E. Reed,et al.  Gli1 contributes to cellular resistance to cisplatin through altered cellular accumulation of the drug , 2014, Oncology reports.

[4]  A. Bielawska,et al.  2'-hydroxy C16-ceramide induces apoptosis-associated proteomic changes in C6 glioma cells. , 2013, Journal of proteome research.

[5]  E. Reed,et al.  Inhibition of Gli1 results in altered c-Jun activation, inhibition of cisplatin-induced upregulation of ERCC1, XPD and XRCC1, and inhibition of platinum–DNA adduct repair , 2012, Oncogene.

[6]  X. Su,et al.  Stereospecificity of fatty acid 2-hydroxylase and differential functions of 2-hydroxy fatty acid enantiomers[S] , 2012, Journal of Lipid Research.

[7]  H. Hama.  Fatty acid 2-Hydroxylation in mammalian sphingolipid biology. , 2010, Biochimica et biophysica acta.

[8]  P. Escribá,et al.  Minerval induces apoptosis in Jurkat and other cancer cells , 2008, Journal of cellular and molecular medicine.

[9]  S. Tunaru,et al.  Deorphanization of GPR109B as a Receptor for the β-Oxidation Intermediate 3-OH-octanoic Acid and Its Role in the Regulation of Lipolysis* , 2009, The Journal of Biological Chemistry.

[10]  S. Moreno,et al.  Levels of SCS7/FA2H-mediated fatty acid 2-hydroxylation determine the sensitivity of cells to antitumor PM02734. , 2008, Cancer research.