The WT1 Wilms' tumor suppressor gene: how much do we really know?

[1]  J. Licht,et al.  The Transcriptional Effect of WT1 Is Modulated by Choice of Expression Vector (*) , 1995, The Journal of Biological Chemistry.

[2]  E. Reddy,et al.  Cellular Factors Binding to a Novel cis-Acting Element Mediate Steroid Hormone Responsiveness of Mouse Mammary Tumor Virus Promoter (*) , 1995, The Journal of Biological Chemistry.

[3]  D. Haber,et al.  WT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosis. , 1995, The EMBO journal.

[4]  D. Haber,et al.  The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis. , 1995, Genes & development.

[5]  J. Licht,et al.  The tumor suppressor gene WT1 inhibits ras-mediated transformation. , 1995, Oncogene.

[6]  H. Werner,et al.  Inhibition of cellular proliferation by the Wilms' tumor suppressor WT1 is associated with suppression of insulin-like growth factor I receptor gene expression , 1995, Molecular and cellular biology.

[7]  K. Miyagawa,et al.  Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing , 1995, Cell.

[8]  J. Licht,et al.  WT1-mediated Transcriptional Activation Is Inhibited by Dominant Negative Mutant Proteins (*) , 1995, The Journal of Biological Chemistry.

[9]  Y. Wu,et al.  GATA-1 Transactivates the WT1 Hematopoietic Specific Enhancer (*) , 1995, The Journal of Biological Chemistry.

[10]  J. Pelletier,et al.  Repression of the retinoic acid receptor-alpha gene by the Wilms' tumor suppressor gene product, wt1. , 1995, Oncogene.

[11]  Z. Wang,et al.  WT1, the Wilms' tumor suppressor gene product, represses transcription through an interactive nuclear protein. , 1995, Oncogene.

[12]  D. Housman,et al.  Sequence and structural requirements for high-affinity DNA binding by the WT1 gene product , 1995, Molecular and cellular biology.

[13]  J. Morris,et al.  Repression of Pax-2 by WT1 during normal kidney development. , 1995, Development.

[14]  Y. Akasaka,et al.  A critical mutation in both WT1 alleles is not sufficient to cause Wilms' tumor , 1995, FEBS letters.

[15]  Z. Wang,et al.  Products of alternatively spliced transcripts of the Wilms' tumor suppressor gene, wt1, have altered DNA binding specificity and regulate transcription in different ways. , 1995, Oncogene.

[16]  A. Hagemeijer,et al.  Expression of the wilms' tumor gene WT1 in human malignant mesothelioma cell lines and relationship to platelet‐derived growth factor A and insulin‐like growth factor 2 expression , 1995, Genes, chromosomes & cancer.

[17]  J. Morris,et al.  Wilms' tumor 1 susceptibility (WT1) gene products are selectively expressed in malignant mesothelioma. , 1995, The American journal of pathology.

[18]  V. Rangnekar,et al.  The zinc finger transcription factor EGR-1 impedes interleukin-1-inducible tumor growth arrest , 1995, Molecular and cellular biology.

[19]  P. Romaniuk,et al.  High affinity binding sites for the Wilms' tumour suppressor protein WT1. , 1995, Nucleic acids research.

[20]  J. Pelletier,et al.  Clonal expansion and attenuated apoptosis in Wilms' tumors are associated with p53 gene mutations. , 1995, Cancer research.

[21]  J. Brieger,et al.  The expression of the Wilms' tumor gene in acute myelocytic leukemias as a possible marker for leukemic blast cells. , 1994, Leukemia.

[22]  T. Hunter,et al.  Cyclins and cancer II: Cyclin D and CDK inhibitors come of age , 1994, Cell.

[23]  T. Akiyama,et al.  WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia. , 1994, Blood.

[24]  F. Rauscher,et al.  Novel replication inhibitory function of the developmental regulator/transcription repressor protein WT1 encoded by the Wilms' tumor gene. , 1994, Oncogene.

[25]  M. Ouchida,et al.  The EWS gene, involved in Ewing family of tumors, malignant melanoma of soft parts and desmoplastic small round cell tumors, codes for an RNA binding protein with novel regulatory domains. , 1994, Oncogene.

[26]  E. Thiel,et al.  Expression of the WT1 Wilms' tumor gene by normal and malignant human melanocytes , 1994, International journal of cancer.

[27]  J. Renshaw,et al.  The Wilms tumour (WT1) gene is mutated in a secondary leukaemia in a WAGR patient. , 1994, Human molecular genetics.

[28]  D. Fisher Apoptosis in cancer therapy: Crossing the threshold , 1994, Cell.

[29]  R. Lothe,et al.  Association studies of a polymorphism in the Wilms' tumor 1 locus in norwegian patients with testicular cancer , 1994, International journal of cancer.

[30]  K. Malik,et al.  Autoregulation of the human WT1 gene promoter , 1994, FEBS letters.

[31]  Osamu Ogawa,et al.  Cloning of novel Wilms tumor gene (WT1) cDNAs; evidence for antisense transcription of WT1. , 1994, Oncogene.

[32]  A. Feinberg,et al.  Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour , 1994, Nature Genetics.

[33]  H. Pass,et al.  Wilms' tumor suppressor gene expression in rat and human mesothelioma. , 1994, Cancer research.

[34]  J. Licht,et al.  Mapping and mutagenesis of the amino-terminal transcriptional repression domain of the Drosophila Krüppel protein , 1994, Molecular and cellular biology.

[35]  J. Pelletier,et al.  WT1 mutations associated with incomplete Denys-Drash syndrome define a domain predicted to behave in a dominant-negative fashion. , 1994, Genomics.

[36]  W. Gerald,et al.  Fusion of the EWS and WT1 genes in the desmoplastic small round cell tumor. , 1994, Cancer research.

[37]  V. Sukhatme,et al.  DNA recognition by splicing variants of the Wilms' tumor suppressor, WT1 , 1994, Molecular and cellular biology.

[38]  A. Viel,et al.  Molecular mechanisms possibly affecting WT1 function in human ovarian tumors , 1994, International journal of cancer.

[39]  D. Sens,et al.  Distinctive properties of an anaplastic Wilms' tumor and its associated epithelial cell line. , 1994, The American journal of pathology.

[40]  D. Mercola,et al.  Suppression of v-sis-dependent transformation by the transcription factor, Egr-1. , 1994, Oncogene.

[41]  N. Nowak,et al.  Anaplastic Wilms' tumour, a subtype displaying poor prognosis, harbours p53 gene mutations , 1994, Nature Genetics.

[42]  M. Sporn,et al.  Repression of the transforming growth factor-beta 1 gene by the Wilms' tumor suppressor WT1 gene product. , 1994, Molecular endocrinology.

[43]  V. Sukhatme,et al.  Transcriptional repression of the insulin-like growth factor I receptor (IGF-I-R) gene by the tumor suppressor WT1 involves binding to sequences both upstream and downstream of the IGF-I-R gene transcription start site. , 1994, The Journal of biological chemistry.

[44]  B. Williams,et al.  Mutations of the p53 tumor suppressor gene occur infrequently in Wilms' tumor. , 1994, Cancer research.

[45]  K. Imai,et al.  Downregulation of Wilms' tumor gene (wt1) during myelomonocytic differentiation in HL60 cells. , 1994, Blood.

[46]  S. Hewitt,et al.  Transcriptional regulation of the human Wilms' tumor gene (WT1). Cell type-specific enhancer and promiscuous promoter. , 1994, The Journal of biological chemistry.

[47]  S. Sukumar,et al.  RNA editing in the Wilms' tumor susceptibility gene, WT1. , 1994, Genes & development.

[48]  N. Niikawa,et al.  Mosaic and polymorphic imprinting of the WT1 gene in humans , 1994, Nature Genetics.

[49]  L. Looijenga,et al.  Testicular germ cell tumors of adults show deletions of chromosomal bands 11 p13 and 11p15.5, but no abnormalities within the zinc‐finger regions and exons 2 and 6 of the wilms' Tumor 1 Gene , 1994, Genes, chromosomes & cancer.

[50]  S. Madden,et al.  The Wilms' tumor suppressor gene WT1 is negatively autoregulated. , 1994, The Journal of biological chemistry.

[51]  Frank Costantini,et al.  Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret , 1994, Nature.

[52]  R. Weinberg,et al.  Tumor spectrum analysis in p53-mutant mice , 1994, Current Biology.

[53]  D. Haber,et al.  WT1-mediated growth suppression of Wilms tumor cells expressing a WT1 splicing variant. , 1993, Science.

[54]  G. Saunders,et al.  Wilms tumor genes. , 1993, Biochimica et biophysica acta.

[55]  P. Waber,et al.  Infrequency of ras, p53, WT1, or RB gene alterations in Wilms tumors , 1993, Cancer.

[56]  J. Sage,et al.  Transmeiotic differentiation of male germ cells in culture , 1993, Cell.

[57]  M. Eccles,et al.  Constitutional relaxation of insulin–like growth factor II gene imprinting associated with Wilms' tumour and gigantism , 1993, Nature Genetics.

[58]  S. Mundlos,et al.  Nuclear localization of the protein encoded by the Wilms' tumor gene WT1 in embryonic and adult tissues. , 1993, Development.

[59]  Amy Bernard,et al.  Inactivation of WT1 in nephrogenic rests, genetic precursors to Wilms' tumour , 1993, Nature Genetics.

[60]  F. Costantini,et al.  Expression of the c-ret proto-oncogene during mouse embryogenesis. , 1993, Development.

[61]  W. Hofmann,et al.  Characterization of the transcriptional regulatory region of the human WT1 gene. , 1993, Oncogene.

[62]  M. Coppes,et al.  Denys-Drash syndrome: relating a clinical disorder to genetic alterations in the tumor suppressor gene WT1. , 1993, The Journal of pediatrics.

[63]  M. Gessler,et al.  Further evidence that imbalance of WT1 isoforms may be involved in Denys-Drash syndrome. , 1993, Human molecular genetics.

[64]  K. Tadokoro,et al.  A novel mutation of the WT1 gene (a tumor suppressor gene for Wilms' tumor) in a patient with Denys-Drash syndrome. , 1993, Human molecular genetics.

[65]  D. Haber,et al.  Altered trans-activational properties of a mutated WT1 gene product in a WAGR-associated Wilms' tumor. , 1993, Cancer research.

[66]  X. Xia,et al.  Inhibition of colony-stimulating factor-1 promoter activity by the product of the Wilms' tumor locus. , 1993, The Journal of biological chemistry.

[67]  N. Maitland,et al.  Low frequency of mutations in the WT1 coding region in Wilms' tumor , 1993, Genes, chromosomes & cancer.

[68]  I. Hughes,et al.  Mutational screening of the Wilms's tumour gene, WT1, in males with genital abnormalities. , 1993, Journal of medical genetics.

[69]  C. Bondy,et al.  Wilms’ tumor (WT1) gene expression in rat decidual differentiation , 1993 .

[70]  P. Radice,et al.  Homozygous intragenic loss of the WT1 locus in a sporadic intralobar wilms' tumor , 1993, International journal of cancer.

[71]  V. Sukhatme,et al.  A novel repression module, an extensive activation domain, and a bipartite nuclear localization signal defined in the immediate-early transcription factor Egr-1 , 1993, Molecular and cellular biology.

[72]  Amy Bernard,et al.  The Wilms tumour gene WT1 is expressed in murine mesoderm–derived tissues and mutated in a human mesothelioma , 1993, Nature Genetics.

[73]  M. Gessler,et al.  Sequence of the WT1 upstream region including the Wit-1 gene. , 1993, Genomics.

[74]  A. Levine,et al.  A comparison of the biological activities of wild‐type and mutant p53 , 1993, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[75]  B. Williams,et al.  The role of WT1 in Wilms tumorigenesis , 1993, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[76]  M. Raff,et al.  Large-scale normal cell death in the developing rat kidney and its reduction by epidermal growth factor. , 1993, Development.

[77]  J. Manley,et al.  Functional domains of the Drosophila Engrailed protein. , 1993, The EMBO journal.

[78]  H. Koeffler,et al.  Expression of the candidate Wilm's tumor gene, WT1, in human leukemia cells. , 1993, Leukemia.

[79]  B. Tycko,et al.  Imprinting of human H19: allele-specific CpG methylation, loss of the active allele in Wilms tumor, and potential for somatic allele switching. , 1993, American journal of human genetics.

[80]  M. Gessler,et al.  Homozygous inactivation of WTI in a Wilms' tumor associated with the WAGR syndrome , 1993, Genes, chromosomes & cancer.

[81]  D. Cook,et al.  A structure-function analysis of transcriptional repression mediated by the WT1, Wilms' tumor suppressor protein. , 1993, Oncogene.

[82]  B. Williams,et al.  Analysis of WT1 in granulosa cell and other sex cord-stromal tumors. , 1993, Cancer research.

[83]  R. Lothe,et al.  Frequent loss of 11p13 and 11p15 loci in male germ cell tumours , 1993, Genes, chromosomes & cancer.

[84]  Y. Tsunematsu,et al.  Deletion of WT1 and WIT1 Genes and Loss of Heterozygosity on Chromosome 11p in Wilms Tumors in Japan , 1993, Japanese journal of cancer research : Gann.

[85]  Z. Wang,et al.  The Wilms' tumor gene product WT1 activates or suppresses transcription through separate functional domains. , 1993, The Journal of biological chemistry.

[86]  M. Biggin,et al.  Cooperative binding at a distance by even-skipped protein correlates with repression and suggests a mechanism of silencing , 1993, Molecular and cellular biology.

[87]  A. Feinberg,et al.  Relaxation of imprinted genes in human cancer , 1993, Nature.

[88]  M. Eccles,et al.  Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour , 1993, Nature.

[89]  A. Kelsey,et al.  Evidence that WT1 mutations in Denys-Drash syndrome patients may act in a dominant-negative fashion. , 1993, Human molecular genetics.

[90]  J. Manley,et al.  Transcriptional repression by the Drosophila even-skipped protein: definition of a minimal repression domain. , 1993, Genes & development.

[91]  Y. Akasaka,et al.  A point mutation found in the WT1 gene in a sporadic Wilms' tumor without genitourinary abnormalities is identical with the most frequent point mutation in Denys‐Drash syndrome , 1993, FEBS letters.

[92]  M. Eccles,et al.  A novel insertional mutation at the third zinc finger coding region of the WT1 gene in Denys-Drash syndrome. , 1993, Human molecular genetics.

[93]  J. Bard,et al.  The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryo , 1993, Mechanisms of Development.

[94]  P. van Oostveldt,et al.  Identification of the cellular protein encoded by the human Wilms' tumor (WT1) gene. , 1992, Oncogene.

[95]  Q. Al-Awqati,et al.  Apoptosis in metanephric development , 1992, The Journal of cell biology.

[96]  S. Sukumar,et al.  Molecular cloning of rat Wilms' tumor complementary DNA and a study of messenger RNA expression in the urogenital system and the brain. , 1992, Cancer research.

[97]  Z. Wang,et al.  The Wilms' tumor gene product, WT1, represses transcription of the platelet-derived growth factor A-chain gene. , 1992, The Journal of biological chemistry.

[98]  R. Weksberg,et al.  Loss of heterozygosity mapping in Wilms tumor indicates the involvement of three distinct regions and a limited role for nondisjunction or mitotic recombination , 1992, Genes, chromosomes & cancer.

[99]  B. Williams,et al.  Inherited WT1 mutation in Denys-Drash syndrome. , 1992, Cancer research.

[100]  N. Lemoine,et al.  Aberrant expression of the tumour suppressor gene p53 is very frequent in Wilms' tumours , 1992, The Journal of pathology.

[101]  R. Weinberg,et al.  Effects of an Rb mutation in the mouse , 1992, Nature.

[102]  L. Saxén,et al.  Transient expression of syndecan in mesenchymal cell aggregates of the embryonic kidney. , 1992, Developmental biology.

[103]  J. Cowell,et al.  Constitutional mutations in the WT1 gene in patients with Denys-Drash syndrome. , 1992, Human molecular genetics.

[104]  G I Bell,et al.  Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1. , 1992, Science.

[105]  W. Bickmore,et al.  Modulation of DNA binding specificity by alternative splicing of the Wilms tumor wt1 gene transcript. , 1992, Science.

[106]  R. Brent,et al.  Fused protein domains inhibit DNA binding by LexA , 1992, Molecular and cellular biology.

[107]  K. Tadokoro,et al.  Intragenic homozygous deletion of the WT1 gene in Wilms' tumor. , 1992, Oncogene.

[108]  A. Feinberg,et al.  A third Wilms' tumor locus on chromosome 16q. , 1992, Cancer research.

[109]  D. Housman,et al.  Germline intronic and exonic mutations in the Wilms' tumour gene (WT1) affecting urogenital development , 1992, Nature Genetics.

[110]  W. Gerald,et al.  Expression of the 11p13 Wilms' tumor gene, WT1, correlates with histologic category of Wilms' tumor. , 1992, The American journal of pathology.

[111]  G. Saunders,et al.  Expression of the Wilms' tumor gene (WT1) in human leukemias. , 1992, Leukemia.

[112]  P. Berry,et al.  Inactivation of the remaining allele of the WT1 gene in a Wilms' tumour from a WAGR patient. , 1992, Oncogene.

[113]  P. Smith,et al.  Equivalent expression of paternally and maternally inherited WT1 alleles in normal fetal tissue and Wilms' tumours. , 1992, Oncogene.

[114]  M. Gessler,et al.  The genomic organization and expression of the WT1 gene. , 1992, Genomics.

[115]  L. Donehower,et al.  Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours , 1992, Nature.

[116]  L. Strong,et al.  RNA expression of the WT1 gene in Wilms' tumors in relation to histology. , 1992, Journal of the National Cancer Institute.

[117]  L. Strong,et al.  Positional cloning and characterization of a paired box- and homeobox-containing gene from the aniridia region , 1991, Cell.

[118]  V. Sukhatme,et al.  Characterization of the zinc finger protein encoded by the WT1 Wilms' tumor locus. , 1991, Oncogene.

[119]  D. Housman,et al.  Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome , 1991, Cell.

[120]  Yang Shi,et al.  Transcriptional repression by YY1, a human GLI-Krüippel-related protein, and relief of repression by adenovirus E1A protein , 1991, Cell.

[121]  D. Housman,et al.  WT1 mutations contribute to abnormal genital system development and hereditary Wilms' tumour , 1991, Nature.

[122]  C. Junien,et al.  The distal region of 11p13 and associated genetic diseases. , 1991, Genomics.

[123]  S. Madden,et al.  Transcriptional repression mediated by the WT1 Wilms tumor gene product. , 1991, Science.

[124]  S. Fleming,et al.  Cell types expressing the Wilms' tumour gene (WT1) in Wilms' tumours: implications for tumour histogenesis. , 1991, Oncogene.

[125]  D. Housman,et al.  Expression of the Wilms' tumor gene WT1 in the murine urogenital system. , 1991, Genes & development.

[126]  N. Pavletich,et al.  Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A , 1991, Science.

[127]  D. Housman,et al.  Evidence for WT1 as a Wilms tumor (WT) gene: intragenic germinal deletion in bilateral WT. , 1991, American journal of human genetics.

[128]  D. Housman,et al.  Structural rearrangements of the WT1 gene in Wilms' tumour cells. , 1991, Oncogene.

[129]  D. Housman,et al.  Isolation, characterization, and expression of the murine Wilms' tumor gene (WT1) during kidney development , 1991, Molecular and cellular biology.

[130]  A. Poustka,et al.  Direct pulsed field gel electrophoresis of Wilms' tumors shows that dna deletions in 11 p 13 are rare , 1991, Genes, chromosomes & cancer.

[131]  T. Curran,et al.  Binding of the Wilms' tumor locus zinc finger protein to the EGR-1 consensus sequence. , 1990, Science.

[132]  A. Feinberg,et al.  Wilms tumor locus on 11p13 defined by multiple CpG island-associated transcripts. , 1990, Science.

[133]  A. Feinberg,et al.  Tissue, developmental, and tumor-specific expression of divergent transcripts in Wilms tumor. , 1990, Science.

[134]  D. Housman,et al.  A mouse model of the aniridia-Wilms tumor deletion syndrome. , 1990, Science.

[135]  T. Barratt,et al.  Clinicopathologic review of twelve children with nephropathy, Wilms tumor, and genital abnormalities (Drash syndrome). , 1990, The Journal of pediatrics.

[136]  J. Cowell,et al.  Preferential loss of maternal alleles in sporadic Wilms' tumour. , 1990, Oncogene.

[137]  P. Gruss,et al.  Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system. , 1990, Development.

[138]  J. Bard,et al.  The candidate Wilms' tumour gene is involved in genitourinary development , 1990, Nature.

[139]  L. Strong,et al.  Parental origin of de novo constitutional deletions of chromosomal band 11p13. , 1990, American journal of human genetics.

[140]  D. Housman,et al.  An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor , 1990, Cell.

[141]  R. Koski,et al.  Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals , 1990, Molecular and cellular biology.

[142]  A. Poustka,et al.  Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping , 1990, Nature.

[143]  D. Housman,et al.  Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus , 1990, Cell.

[144]  T. Gansler,et al.  Antibody to type I insulinlike growth factor receptor inhibits growth of Wilms' tumor in culture and in athymic mice. , 1989, The American journal of pathology.

[145]  M. Levine,et al.  Transcriptional repression of eukaryotic promoters , 1989, Cell.

[146]  E. A. O'neill,et al.  The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain , 1989, Cell.

[147]  W. Cavenee,et al.  Familial Wiedemann-Beckwith syndrome and a second Wilms tumor locus both map to 11p15.5. , 1989, American journal of human genetics.

[148]  R. Tjian,et al.  Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif , 1988, Cell.

[149]  M. Ptashne How eukaryotic transcriptional activators work , 1988, Nature.

[150]  H. Chan,et al.  Homozygous deletion of a DNA marker from chromosome 11p13 in sporadic Wilms tumor. , 1988, Genomics.

[151]  C. Goridis,et al.  Neural cell adhesion molecules during embryonic induction and development of the kidney. , 1988, Development.

[152]  D. Bowen-Pope,et al.  Production of platelet‐derived growth factor by cultured Wilms' tumor cells and fetal kidney cells , 1987, Journal of cellular physiology.

[153]  J. Scott,et al.  Insulin-like growth factor-II gene expression in Wilms' tumour and embryonic tissues , 1985, Nature.

[154]  M. Eccles,et al.  Expression of insulin-like growth factor-II transcripts in Wilms' tumour , 1985, Nature.

[155]  S. Orkin,et al.  Development of homozygosity for chromosome 11p markers in Wilms' tumour , 1984, Nature.

[156]  A. Feinberg,et al.  Somatic deletion and duplication of genes on chromosome 11 in Wilms' tumours , 1984, Nature.

[157]  N. Copeland,et al.  Loss of alleles at loci on human chromosome 11 during genesis of Wilms' tumour , 1984, Nature.

[158]  A. Reeve,et al.  Loss of a Harvey ras allele in sporadic Wilms' tumour , 1984, Nature.

[159]  U. Francke,et al.  Chromosomal imbalance in the Aniridia-Wilms' tumor association: 11p interstitial deletion. , 1978, Pediatrics.

[160]  A. Knudson,et al.  Mutation and cancer: a model for Wilms' tumor of the kidney. , 1972, Journal of the National Cancer Institute.

[161]  L. Strong,et al.  WT1 exon 1 deletion/insertion mutations in Wilms tumor patients, associated with di- and trinucleotide repeats and deletion hotspot consensus sequences. , 1995, American journal of human genetics.

[162]  B. Williams,et al.  Antisense transcripts and protein binding motifs within the Wilms tumour (WT1) locus. , 1994, Oncogene.

[163]  N. Hastie,et al.  The genetics of Wilms' tumor--a case of disrupted development. , 1994, Annual review of genetics.

[164]  M. Eccles,et al.  Expression of WT1 protein in fetal kidneys and Wilms tumors. , 1994, Laboratory investigation; a journal of technical methods and pathology.

[165]  S. Orkin,et al.  Infrequent mutation of the WT1 gene in 77 Wilms' tumors , 1994, Human mutation.

[166]  D. Housman,et al.  Analysis of the 11p13 Wilms' tumor suppressor gene (WT1) in ovarian tumors. , 1993, Cancer investigation.

[167]  N. Hastie,et al.  Wilms' tumour: reconciling genetics and biology. , 1992, Trends in genetics : TIG.

[168]  A. Umezawa,et al.  Genomic changes in the WT-gene (WT1) in Wilms' tumors and their correlation with histology. , 1992, The American journal of pathology.

[169]  D. Housman,et al.  Identification of mutations in the WT1 gene in tumours from patients with the WAGR syndrome. , 1992, Oncogene.

[170]  Hans Clevers,et al.  Reprints Available Directly from the Publisher Photocopying Permitted by License Only Expression of Gata-3 during Lymphocyte Differentiation and Mouse Embryogenesis , 2022 .

[171]  N. Kiviat,et al.  Nephrogenic rests, nephroblastomatosis, and the pathogenesis of Wilms' tumor. , 1990, Pediatric pathology.

[172]  L. Saxén Organogenesis of the kidney , 1987 .

[173]  U. Francke,et al.  Aniridia-Wilms' tumor association: evidence for specific deletion of 11p13. , 1979, Cytogenetics and cell genetics.