Use of Caval Subtraction 2D Phase-Contrast MR Imaging to Measure Total Liver and Hepatic Arterial Blood Flow: Preclinical Validation and Initial Clinical Translation

Caval subtraction phase-contrast MR imaging is technically feasible and may offer a reproducible and clinically viable method for measuring total liver blood flow and hepatic arterial flow.

[1]  R. Omary,et al.  Respiratory self‐gating for free‐breathing abdominal phase‐contrast blood flow measurements , 2009, Journal of magnetic resonance imaging : JMRI.

[2]  M. Menger,et al.  Loss of Physiologic Hepatic Blood Flow Control (“Hepatic Arterial Buffer Response”) During CO2-Pneumoperitoneum in the Rat , 2001, Anesthesia and analgesia.

[3]  H. Rusinek,et al.  Perfusion imaging of the liver: current challenges and future goals. , 2005, Radiology.

[4]  P. Abel,et al.  Reproducibility of Quantitative Assessment of Altered Hepatic Hemodynamics With Dynamic Contrast‐Enhanced Ultrasound , 2012, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[5]  C. Meier,et al.  Cardiovascular flow measurement with phase-contrast MR imaging: basic facts and implementation. , 2002, Radiographics : a review publication of the Radiological Society of North America, Inc.

[6]  K. Moore,et al.  Increased sensitivity to endotoxemia in the bile duct–ligated cirrhotic rat , 1999, Hepatology.

[7]  Vincent Mallet,et al.  Chronic Liver Disease: Systemic and Splanchnic Venous Flow Mapping with Optimized Cine Phase-Contrast MR Imaging Validated in a Phantom Model and Prospectively Evaluated in Patients1 , 2011 .

[8]  R. Jalan,et al.  Systemic inflammation is associated with increased intrahepatic resistance and mortality in alcohol‐related acute‐on‐chronic liver failure , 2015, Liver international : official journal of the International Association for the Study of the Liver.

[9]  J. Ridgway,et al.  Measurement of hepatic arterial flow using phase contrast magnetic resonance imaging , 2009, Physics in medicine and biology.

[10]  A. Burroughs,et al.  Targeting portal pressure measurements: A critical reappraisal , 2004, Hepatology.

[11]  B. Taouli,et al.  Quantitative Liver MRI Combining Phase Contrast Imaging, Elastography, and DWI: Assessment of Reproducibility and Postprandial Effect at 3.0 T , 2014, PloS one.

[12]  M. Meyer,et al.  Hepatic vascular flow measurements by phase contrast MRI and doppler echography: A comparative and reproducibility study , 2010, Journal of magnetic resonance imaging : JMRI.

[13]  Michael Markl,et al.  MR‐based visualization and quantification of three‐dimensional flow characteristics in the portal venous system , 2010, Journal of magnetic resonance imaging : JMRI.

[14]  C. Dejong,et al.  Accurate perioperative flow measurement of the portal vein and hepatic and renal artery: a role for preoperative MRI? , 2012, European journal of radiology.

[15]  Y. Kinosada,et al.  Single photon emission computed tomography to determine effective hepatic blood flow and intrahepatic shunting , 1995, Hepatology.

[16]  J. Hiatt,et al.  Surgical Anatomy of the Hepatic Arteries in 1000 Cases , 1994, Annals of surgery.

[17]  Jae Hyung Park,et al.  Celiac axis and common hepatic artery variations in 5002 patients: systematic analysis with spiral CT and DSA. , 2010, Radiology.

[18]  Johannes Forkman,et al.  Estimator and Tests for Common Coefficients of Variation in Normal Distributions , 2009 .

[19]  K. Brown,et al.  Variant hepatic arterial anatomy revisited: digital subtraction angiography performed in 600 patients. , 2002, Radiology.

[20]  J. Regimbeau,et al.  Dynamic measurements of total hepatic blood flow with Phase Contrast MRI. , 2010, European journal of radiology.

[21]  R. Jeffrey,et al.  Magnetic resonance imaging and hepatic hemodynamics: correlation with metabolic function in liver transplantation candidates. , 1995, Surgery.

[22]  Yu-Chung N. Cheng,et al.  Magnetic Resonance Imaging: Physical Principles and Sequence Design , 1999 .