Variants in CHEK2 other than 1100delC do not make a major contribution to breast cancer susceptibility.
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Nazneen Rahman | Carel Meijers | Sheila Seal | Diana Eccles | Douglas F Easton | Michael R Stratton | Mieke Schutte | D Gareth Evans | Frans Lohman | S. Seal | M. Stratton | N. Rahman | P. Futreal | J. Klijn | D. Easton | B. Weber | M. Schutte | D. Eccles | D. Evans | H. Meijers-Heijboer | K. Nathanson | A. V. D. van den Ouweland | R. Barfoot | P. A. Futreal | C. Meijers | P Andrew Futreal | Barbara L Weber | Katherine L Nathanson | Rita Barfoot | Hanne Meijers-Heijboer | Ans van den Ouweland | Marijke Wasielewski | Jan Klijn | Marijke Wasielewski | F. Lohman | D. Evans | Michael R. Stratton | M. Stratton
[1] D. Stern,et al. Chk2 Activation and Phosphorylation-Dependent Oligomerization , 2002, Molecular and Cellular Biology.
[2] Michael B Yaffe,et al. Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2. , 2002, Molecular cell.
[3] T. Halazonetis,et al. Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53. , 2000, Genes & development.
[4] R. Eeles,et al. A robust method for detecting CHK2/RAD53 mutations in genomic DNA , 2002, Human mutation.
[5] Jing Chen,et al. Characterization of Tumor-associated Chk2 Mutations* , 2001, The Journal of Biological Chemistry.
[6] N. Mailand,et al. The ATM–Chk2–Cdc25A checkpoint pathway guards against radioresistant DNA synthesis , 2001, Nature.
[7] J. Bartek,et al. Chk2 kinase — a busy messenger , 2001, Nature Reviews Molecular Cell Biology.
[8] L. Aaltonen,et al. p53, CHK2, and CHK1 genes in Finnish families with Li-Fraumeni syndrome: further evidence of CHK2 in inherited cancer predisposition. , 2001, Cancer research.
[9] K. Isselbacher,et al. Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome. , 1999, Science.
[10] Peter Devilee,et al. BRCA1 genomic deletions are major founder mutations in Dutch breast cancer patients , 1997, Nature Genetics.
[11] Nazneen Rahman,et al. Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 or BRCA2 mutations , 2002, Nature Genetics.
[12] S. Elledge,et al. Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[13] D. Durocher,et al. The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms. , 2000, Molecular cell.
[14] R. Winqvist,et al. Mutation analysis of the CHK2 gene in families with hereditary breast cancer , 2001, British Journal of Cancer.
[15] B. Gusterson,et al. Analysis of CHK2 in vulval neoplasia , 2002, British Journal of Cancer.
[16] O. Delattre,et al. Detection of 11 germline inactivating TP53 mutations and absence of TP63 andHCHK2 mutations in 17 French families with Li-Fraumeni or Li-Fraumeni-like syndrome , 2001, Journal of medical genetics.
[17] D J Prockop,et al. Conformation-sensitive gel electrophoresis for rapid detection of single-base differences in double-stranded PCR products and DNA fragments: evidence for solvent-induced bends in DNA heteroduplexes. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[18] O. Kallioniemi,et al. A CHEK2 genetic variant contributing to a substantial fraction of familial breast cancer. , 2002, American journal of human genetics.
[19] B. Gusterson,et al. Concomitant inactivation of p53 and Chk2 in breast cancer , 2002, Oncogene.
[20] R. Barkardottir,et al. Mutation analysis of the CHK2 gene in breast carcinoma and other cancers , 2001, Breast Cancer Research.
[21] W. Hofmann,et al. Mutation analysis of the DNA-damage checkpoint gene CHK2 in myelodysplastic syndromes and acute myeloid leukemias. , 2001, Leukemia research.
[22] S. Elledge,et al. The DNA damage response: putting checkpoints in perspective , 2000, Nature.
[23] C. O. Parker,et al. The North Cumbria Community Genetics Project. , 1998, Journal of medical genetics.
[24] S. Moreno,et al. Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1 , 1998, Nature.
[25] Jong-Soo Lee,et al. hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response , 2000, Nature.
[26] D. Sgroi,et al. Destabilization of CHK2 by a missense mutation associated with Li-Fraumeni Syndrome. , 2001, Cancer research.
[27] S. Elledge,et al. Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. , 1998, Science.
[28] H.-H. Essen,et al. Microseismological evidence for a changing wave climate in the northeast Atlantic Ocean , 2000, Nature.