Acute Appendicitis Complicated by Septic Thrombophlebitis of the Portal Vein Shown by 18F-FDG and 68Ga-FAPI-46 PET/CT.

ABSTRACT Septic thrombophlebitis of the portal vein is a serious infectious disorder and is difficult to be diagnosed at an early stage. In this case, we presented 18F-FDG and 68Ga-FAPI-46 PET/CT findings in a 45-year-old man with acute appendicitis complicated by septic thrombophlebitis of the portal vein. 68Ga-FAPI-46 PET/CT showed intense radiotracer uptake in the thrombosis of the portal vein, with higher SUVmax and larger disease extent than 18F-FDG PET/CT. This case demonstrated that 68Ga-FAPI PET/CT may be a useful imaging modality for the diagnosis of this infectious condition.