论文信息 - Farklý Kültür ve Ýnkübasyon Modellerinin Oosit Ýn-Vitro Maturasyonuna Etkileri THE EFFECTS OF DIFFERENT CULTURE AND INCUBATION MODELS ON OOCYT IN-VITRO MATURATION

Farklý Kültür ve Ýnkübasyon Modellerinin Oosit Ýn-Vitro Maturasyonuna Etkileri THE EFFECTS OF DIFFERENT CULTURE AND INCUBATION MODELS ON OOCYT IN-VITRO MATURATION

lu ovarian hiperstimulasyondan (KOH) sonra, genellikle 16-25 mm capýndaki follikullerden toplanan olgun oositlerde, inseminasyon zamaný, oosit toplama (oocyte pick-up) iþleminden sonraki ilk 4-6 saatler arasýndadýr. Bu zaman aralýðý gebelik þansýný arttýran bir faktordur (1,2). Genellikle 16 mm'den kucuk caplý follikullerden toplanan germinal vezikul (GV)'un gorulduðu immatur (Profaz I) ve intermediate (Metafaz I) oositlerin ise olgunlaþma sureleri, kultur ortamý icinde, in-vitro olarak devam eder. Matur olmayan bu oositlerin in-vitro maturasyon (IVM) surecinden gecmeleri gerekmektedir. Ýn-vitro fertilizasyonda (IVF) baþarýsýzlýk oranýnýn buyuk bir kýsmýný oosit immaturitesi oluþturmaktadýr (3-6).

M. Cıncık | Cem Korkmaz | Ömer Coþkun | Þaban Sezen | H. Özsoy

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