An advanced monitoring platform for rational design of recombinant processes.

Bioprocess engineering is an application-oriented science in an interdisciplinary environment, and a meaningful combination of different scientific disciplines is the only way to meet the challenges of bioprocess complexity. Setting up a reasoned process monitoring platform is the first step in an iterative procedure aiming at process and systems understanding, being the key to rational and innovative bioprocess design. This chapter describes a comprehensive process monitoring platform and how the resulting knowledge is translated into new strategies in process and/or host cell design.

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