Toxicity, Uptake, and Translocation of Engineered Nanomaterials in Vascular plants.

To exploit the promised benefits of engineered nanomaterials, it is necessary to improve our knowledge of their bioavailability and toxicity. The interactions between engineered nanomaterials and vascular plants are of particular concern, as plants closely interact with soil, water, and the atmosphere, and constitute one of the main routes of exposure for higher species, i.e. accumulation through the food chain. A review of the current literature shows contradictory evidence on the phytotoxicity of engineered nanomaterials. The mechanisms by which engineered nanomaterials penetrate plants are not well understood, and further research on their interactions with vascular plants is required to enable the field of phytotoxicology to keep pace with that of nanotechnology, the rapid evolution of which constantly produces new materials and applications that accelerate the environmental release of nanomaterials.

[1]  J. White,et al.  Toxicity of silver and copper to Cucurbita pepo: Differential effects of nano and bulk‐size particles , 2012, Environmental toxicology.

[2]  J. White,et al.  Xylem- and phloem-based transport of CuO nanoparticles in maize (Zea mays L.). , 2012, Environmental science & technology.

[3]  B. Arey,et al.  Nanospecific inhibition of pyoverdine siderophore production in Pseudomonas chlororaphis O6 by CuO nanoparticles. , 2012, Chemical research in toxicology.

[4]  A. Biris,et al.  Carbon nanotubes induce growth enhancement of tobacco cells. , 2012, ACS nano.

[5]  Y. An,et al.  Effect of silver nanoparticles in crop plants Phaseolus radiatus and Sorghum bicolor: media effect on phytotoxicity. , 2012, Chemosphere.

[6]  Z. Chai,et al.  Comparative toxicity of nanoparticulate/bulk Yb₂O₃ and YbCl₃ to cucumber (Cucumis sativus). , 2012, Environmental science & technology.

[7]  E. Joner,et al.  Impact of Fe and Ag nanoparticles on seed germination and differences in bioavailability during exposure in aqueous suspension and soil , 2012, Environmental toxicology.

[8]  Z. Chai,et al.  Phytotoxicity and biotransformation of La2O3 nanoparticles in a terrestrial plant cucumber (Cucumis sativus) , 2011, Nanotoxicology.

[9]  Tinh Nguyen,et al.  Potential release pathways, environmental fate, and ecological risks of carbon nanotubes. , 2011, Environmental science & technology.

[10]  Hai-feng Zhang,et al.  Uptake and distribution of ceria nanoparticles in cucumber plants. , 2011, Metallomics : integrated biometal science.

[11]  J. Peralta-Videa,et al.  Spectroscopic verification of zinc absorption and distribution in the desert plant Prosopis juliflora-velutina (velvet mesquite) treated with ZnO nanoparticles. , 2011, Chemical engineering journal.

[12]  J. Peralta-Videa,et al.  Toxicity and biotransformation of ZnO nanoparticles in the desert plants Prosopis juliflora-velutina, Salsola tragus and Parkinsonia florida , 2011 .

[13]  J. Kurepa,et al.  Ultra-small TiO(2) nanoparticles disrupt microtubular networks in Arabidopsis thaliana. , 2011, Plant, cell & environment.

[14]  Wenchao Du,et al.  TiO2 and ZnO nanoparticles negatively affect wheat growth and soil enzyme activities in agricultural soil. , 2011, Journal of environmental monitoring : JEM.

[15]  E. Basiuk,et al.  Ecotoxicological effects of carbon nanomaterials on algae, fungi and plants. , 2011, Journal of nanoscience and nanotechnology.

[16]  Jose R Peralta-Videa,et al.  Interaction of nanoparticles with edible plants and their possible implications in the food chain. , 2011, Journal of agricultural and food chemistry.

[17]  Mark R. Wiesner,et al.  Estimating production data for five engineered nanomaterials as a basis for exposure assessment. , 2011, Environmental science & technology.

[18]  J. Xiao,et al.  Physiological effects of magnetite (Fe3O4) nanoparticles on perennial ryegrass (Lolium perenne L.) and pumpkin (Cucurbita mixta) plants , 2011, Nanotoxicology.

[19]  Jose R Peralta-Videa,et al.  Nanomaterials and the environment: a review for the biennium 2008-2010. , 2011, Journal of hazardous materials.

[20]  D. Lee,et al.  Hazardous phytotoxic nature of cobalt and zinc oxide nanoparticles assessed using Allium cepa. , 2011, Journal of hazardous materials.

[21]  Maged F. Serag,et al.  Trafficking and subcellular localization of multiwalled carbon nanotubes in plant cells. , 2011, ACS nano.

[22]  Jason M Unrine,et al.  Evidence for biomagnification of gold nanoparticles within a terrestrial food chain. , 2011, Environmental science & technology.

[23]  C. Geri,et al.  The effects of nano-TiO2 on seed germination, development and mitosis of root tip cells of Vicia narbonensis L. and Zea mays L , 2011 .

[24]  V. Zharov,et al.  Complex genetic, photothermal, and photoacoustic analysis of nanoparticle-plant interactions , 2010, Proceedings of the National Academy of Sciences.

[25]  Y. An,et al.  Research Trends of Ecotoxicity of Nanoparticles in Soil Environment , 2010, Toxicological research.

[26]  Diego Rubiales,et al.  Absorption and translocation to the aerial part of magnetic carbon-coated nanoparticles through the root of different crop plants , 2010, Journal of nanobiotechnology.

[27]  Maumita Bandyopadhyay,et al.  Genotoxicity of titanium dioxide (TiO2) nanoparticles at two trophic levels: plant and human lymphocytes. , 2010, Chemosphere.

[28]  Detlef Günther,et al.  No evidence for cerium dioxide nanoparticle translocation in maize plants. , 2010, Environmental science & technology.

[29]  C. Maycock,et al.  The impact of CdSe/ZnS Quantum Dots in cells of Medicago sativa in suspension culture , 2010, Journal of nanobiotechnology.

[30]  Jinxing Lin,et al.  Study of the inhibitory effect of water-soluble fullerenes on plant growth at the cellular level. , 2010, ACS nano.

[31]  N. Yao,et al.  Induction of programmed cell death in Arabidopsis and rice by single-wall carbon nanotubes. , 2010, American journal of botany.

[32]  Guadalupe de la Rosa,et al.  Evidence of the differential biotransformation and genotoxicity of ZnO and CeO2 nanoparticles on soybean (Glycine max) plants. , 2010, Environmental science & technology.

[33]  Yasuhiko Yoshida,et al.  Nanoparticulate material delivery to plants , 2010 .

[34]  D. Lee,et al.  Phytotoxicity of Carbon Nanotubes Assessed by Brassica Juncea and Phaseolus Mungo , 2010 .

[35]  D. Pavlov,et al.  Effect of nanoparticles on aquatic organisms , 2010, Biology Bulletin.

[36]  Yang Deng,et al.  Interactions between engineered nanoparticles (ENPs) and plants: phytotoxicity, uptake and accumulation. , 2010, The Science of the total environment.

[37]  Stefan Vogt,et al.  Uptake and distribution of ultrasmall anatase TiO2 Alizarin red S nanoconjugates in Arabidopsis thaliana. , 2010, Nano letters.

[38]  Jose R Peralta-Videa,et al.  Toxicity and biotransformation of uncoated and coated nickel hydroxide nanoparticles on mesquite plants , 2010, Environmental toxicology and chemistry.

[39]  Xuezhi Zhang,et al.  Trophic transfer of TiO(2) nanoparticles from Daphnia to zebrafish in a simplified freshwater food chain. , 2010, Chemosphere.

[40]  Guadalupe de la Rosa,et al.  X-ray absorption spectroscopy (XAS) corroboration of the uptake and storage of CeO(2) nanoparticles and assessment of their differential toxicity in four edible plant species. , 2010, Journal of agricultural and food chemistry.

[41]  George Huang,et al.  Differential uptake of carbon nanoparticles by plant and Mammalian cells. , 2010, Small.

[42]  Amanda S Barnard,et al.  One-to-one comparison of sunscreen efficacy, aesthetics and potential nanotoxicity. , 2010, Nature nanotechnology.

[43]  K. Leopold,et al.  Pd-nanoparticles cause increased toxicity to kiwifruit pollen compared to soluble Pd(II). , 2010, Environmental pollution.

[44]  Yu-Chang Tsai,et al.  Developmental phytotoxicity of metal oxide nanoparticles to Arabidopsis thaliana , 2010, Environmental toxicology and chemistry.

[45]  Wei Bai,et al.  Effects of rare earth oxide nanoparticles on root elongation of plants. , 2010, Chemosphere.

[46]  B. Fugetsu,et al.  Studies on toxicity of multi-walled carbon nanotubes on suspension rice cells , 2009 .

[47]  Dimitrios Stampoulis,et al.  Assay-dependent phytotoxicity of nanoparticles to plants. , 2009, Environmental science & technology.

[48]  Bing Yan,et al.  Endosomal leakage and nuclear translocation of multiwalled carbon nanotubes: developing a model for cell uptake. , 2009, Nano letters.

[49]  B. Fugetsu,et al.  Studies on toxicity of multi-walled carbon nanotubes on Arabidopsis T87 suspension cells. , 2009, Journal of hazardous materials.

[50]  E. Etxeberria,et al.  Evidence for two endocytic transport pathways in plant cells , 2009 .

[51]  Yang Xu,et al.  Carbon nanotubes are able to penetrate plant seed coat and dramatically affect seed germination and plant growth. , 2009, ACS nano.

[52]  N. Chandrasekaran,et al.  Genotoxicity of silver nanoparticles in Allium cepa. , 2009, The Science of the total environment.

[53]  F. Hennrich,et al.  Selective suspension in aqueous sodium dodecyl sulfate according to electronic structure type allows simple separation of metallic from semiconducting single-walled carbon nanotubes , 2009 .

[54]  Kevin C Jones,et al.  Novel method for the direct visualization of in vivo nanomaterials and chemical interactions in plants. , 2009, Environmental science & technology.

[55]  Priyanka Bhattacharya,et al.  Effects of Quantum Dots Adsorption on Algal Photosynthesis , 2009 .

[56]  F. Hong,et al.  Promotion of nano-anatase TiO(2) on the spectral responses and photochemical activities of D1/D2/Cyt b559 complex of spinach. , 2009, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

[57]  Thomas K. Darlington,et al.  Nanoparticle characteristics affecting environmental fate and transport through soil , 2009, Environmental toxicology and chemistry.

[58]  Qian Hu,et al.  Uptake, translocation, and transmission of carbon nanomaterials in rice plants. , 2009, Small.

[59]  Víctor Puntes,et al.  Evaluation of the ecotoxicity of model nanoparticles. , 2009, Chemosphere.

[60]  P. M. Neumann,et al.  Colloidal suspensions of clay or titanium dioxide nanoparticles can inhibit leaf growth and transpiration via physical effects on root water transport. , 2009, Plant, cell & environment.

[61]  T. Xia,et al.  Potential health impact of nanoparticles. , 2009, Annual review of public health.

[62]  V. Fernández,et al.  Uptake of Hydrophilic Solutes Through Plant Leaves: Current State of Knowledge and Perspectives of Foliar Fertilization , 2009 .

[63]  Xiaohong Fang,et al.  Carbon nanotubes as molecular transporters for walled plant cells. , 2009, Nano letters.

[64]  V. Shah,et al.  Influence of Metal Nanoparticles on the Soil Microbial Community and Germination of Lettuce Seeds , 2009 .

[65]  Insignificant acute toxicity of TiO2 nanoparticles to willow trees , 2009 .

[66]  Xiang-dong Li,et al.  Foliar application of two silica sols reduced cadmium accumulation in rice grains. , 2009, Journal of hazardous materials.

[67]  R. Cremonini,et al.  Nanoparticles and higher plants , 2009 .

[68]  K. Treseder,et al.  The brighter side of soils: quantum dots track organic nitrogen through fungi and plants. , 2009, Ecology.

[69]  Diego Rubiales,et al.  Nanoparticle penetration and transport in living pumpkin plants: in situ subcellular identification , 2009, BMC Plant Biology.

[70]  Hee-Seok Kweon,et al.  Toxicity and bioavailability of copper nanoparticles to the terrestrial plants mung bean (Phaseolus radiatus) and wheat (Triticum aestivum): Plant agar test for water‐insoluble nanoparticles , 2008, Environmental toxicology and chemistry.

[71]  Jamie R Lead,et al.  Nanomaterials in the environment: Behavior, fate, bioavailability, and effects , 2008, Environmental toxicology and chemistry.

[72]  U. Steiner,et al.  Size exclusion limits and lateral heterogeneity of the stomatal foliar uptake pathway for aqueous solutes and water-suspended nanoparticles. , 2008, Physiologia plantarum.

[73]  Anindita Sengupta,et al.  Aqueous toxicity and food chain transfer of quantum dots™ in freshwater algae and Ceriodaphnia dubia , 2008, Environmental toxicology and chemistry.

[74]  Lenore L. Dai,et al.  Effects of functionalized and nonfunctionalized single‐walled carbon nanotubes on root elongation of select crop species , 2008, Environmental toxicology and chemistry.

[75]  Ahmad Musa,et al.  Use of Fe3O4 Nanoparticles for Enhancement of Biosensor Response to the Herbicide 2,4-Dichlorophenoxyacetic Acid , 2008, Sensors.

[76]  M. Elimelech,et al.  Environmental applications of carbon-based nanomaterials. , 2008, Environmental science & technology.

[77]  E. Onelli,et al.  Clathrin-dependent and independent endocytic pathways in tobacco protoplasts revealed by labelling with charged nanogold , 2008, Journal of experimental botany.

[78]  Baoshan Xing,et al.  Root uptake and phytotoxicity of ZnO nanoparticles. , 2008, Environmental science & technology.

[79]  Yan Jin,et al.  Uptake, translocation, and accumulation of manufactured iron oxide nanoparticles by pumpkin plants. , 2008, Journal of environmental monitoring : JEM.

[80]  Nanna B. Hartmann,et al.  Environmental behavior and ecotoxicity of engineered nanoparticles to algae, plants, and fungi , 2008, Ecotoxicology.

[81]  H. Goldbach,et al.  Equivalent pore radii of hydrophilic foliar uptake routes in stomatous and astomatous leaf surfaces--further evidence for a stomatal pathway. , 2008, Physiologia plantarum.

[82]  Mark Crane,et al.  The ecotoxicology and chemistry of manufactured nanoparticles , 2008, Ecotoxicology.

[83]  U. Schmidhalter,et al.  Palladium exposure of barley: uptake and effects. , 2008, Plant biology.

[84]  Reeti Doshi,et al.  Nano-aluminum: transport through sand columns and environmental effects on plants and soil communities. , 2008, Environmental research.

[85]  K. Hungerbühler,et al.  Estimation of cumulative aquatic exposure and risk due to silver: contribution of nano-functionalized plastics and textiles. , 2008, The Science of the total environment.

[86]  Alejandro Pérez-de-Luque,et al.  Nanoparticles as smart treatment-delivery systems in plants: assessment of different techniques of microscopy for their visualization in plant tissues. , 2008, Annals of botany.

[87]  F. Hong,et al.  Was improvement of spinach growth by nano-TiO2 treatment related to the changes of Rubisco activase? , 2008, BioMetals.

[88]  Baoshan Xing,et al.  Phytotoxicity of nanoparticles: inhibition of seed germination and root growth. , 2007, Environmental pollution.

[89]  B. Nowack,et al.  Occurrence, behavior and effects of nanoparticles in the environment. , 2007, Environmental pollution.

[90]  Robert H. Hurt,et al.  Bioavailability of Nickel in Single‐Wall Carbon Nanotubes , 2007 .

[91]  B. Fugetsu,et al.  Multi-Walled Carbon Nanotubes Interact with Cultured Rice Cells: Evidence of a Self-Defense Response , 2007 .

[92]  Richard Handy,et al.  Formulating the problems for environmental risk assessment of nanomaterials. , 2007, Environmental science & technology.

[93]  Robert H. Hurt,et al.  Iron Bioavailability and Redox Activity in Diverse Carbon Nanotube Samples , 2007 .

[94]  V. S. Lin,et al.  Mesoporous silica nanoparticles deliver DNA and chemicals into plants. , 2007, Nature nanotechnology.

[95]  Chao Liu,et al.  Influences of Nano-TiO2 on the chloroplast aging of spinach under light , 2005, Biological Trace Element Research.

[96]  Lang Tran,et al.  Safe handling of nanotechnology , 2006, Nature.

[97]  W. Kreyling,et al.  Health implications of nanoparticles , 2006 .

[98]  E. Baroja-Fernández,et al.  Fluid Phase Endocytic Uptake of Artificial Nano-Spheres and Fluorescent Quantum Dots by Sycamore Cultured Cells , 2006, Plant signaling & behavior.

[99]  Scott C. Brown,et al.  Research strategies for safety evaluation of nanomaterials. Part VI. Characterization of nanoscale particles for toxicological evaluation. , 2006, Toxicological sciences : an official journal of the Society of Toxicology.

[100]  T. Xia,et al.  Toxic Potential of Materials at the Nanolevel , 2006, Science.

[101]  Zhuang Liu,et al.  Carbon nanotubes as intracellular transporters for proteins and DNA: an investigation of the uptake mechanism and pathway. , 2006, Angewandte Chemie.

[102]  Dorina Creanga,et al.  TMA-OH COATED MAGNETIC NANOPARTICLES INTERNALIZED IN VEGETAL TISSUE , 2006 .

[103]  F. Baluška,et al.  Endocytosis and vesicle trafficking during tip growth of root hairs , 2005, Protoplasma.

[104]  H. Dai,et al.  Carbon nanotubes as multifunctional biological transporters and near-infrared agents for selective cancer cell destruction. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[105]  Ling Yang,et al.  Particle surface characteristics may play an important role in phytotoxicity of alumina nanoparticles. , 2005, Toxicology letters.

[106]  C. Larabell,et al.  Quantum dots as cellular probes. , 2005, Annual review of biomedical engineering.

[107]  L. Schreiber Polar paths of diffusion across plant cuticles: new evidence for an old hypothesis. , 2005, Annals of botany.

[108]  A. Murphy,et al.  Endocytotic cycling of PM proteins. , 2005, Annual review of plant biology.

[109]  G. Oberdörster,et al.  Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles , 2005, Environmental health perspectives.

[110]  Mihail C Roco,et al.  Environmentally responsible development of nanotechnology. , 2005, Environmental science & technology.

[111]  S. Gambhir,et al.  Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics , 2005, Science.

[112]  S. Bachilo,et al.  Near-infrared fluorescence microscopy of single-walled carbon nanotubes in phagocytic cells. , 2004, Journal of the American Chemical Society.

[113]  Huajian Gao,et al.  SIMULATION OF DNA-NANOTUBE INTERACTIONS , 2004 .

[114]  F. Baluška,et al.  Endocytosis, Actin Cytoskeleton, and Signaling1 , 2004, Plant Physiology.

[115]  B. Jena,et al.  Regulation of the water channel aquaporin‐1: isolation and reconstitution of the regulatory complex , 2004, Cell biology international.

[116]  M. C. Heath Hypersensitive response-related death , 2000, Plant Molecular Biology.

[117]  V. Colvin The potential environmental impact of engineered nanomaterials , 2003, Nature Biotechnology.

[118]  Joost T. van Dongen,et al.  Structure of the developing pea seed coat and the post-phloem transport pathway of nutrients. , 2003, Annals of botany.

[119]  Wei-xian Zhang,et al.  Nanoscale Iron Particles for Environmental Remediation: An Overview , 2003 .

[120]  G. N. Berestovsky,et al.  Through pore diameter in the cell wall of Chara corallina. , 2001, Journal of experimental botany.

[121]  M. Tester,et al.  Partitioning of nutrient transport processes in roots. , 2001, Journal of experimental botany.

[122]  A. Levine,et al.  The hypersensitive response facilitates plant infection by the necrotrophic pathogen Botrytis cinerea , 2000, Current Biology.

[123]  M. Jaquinod,et al.  Fatty Acid and Lipoic Acid Biosynthesis in Higher Plant Mitochondria* , 2000, The Journal of Biological Chemistry.

[124]  M. Wierzbicka,et al.  The effect of lead on seed imbibition and germination in different plant species , 1998 .

[125]  A. Chesson,et al.  Cell wall porosity and available surface area of wheat straw and wheat grain fractions , 1997 .

[126]  C. Hawes,et al.  Endocytosis in plants: fact or artefact? , 1995 .

[127]  G. Buchan,et al.  The role of surface tension of spreading droplets in absorption of a herbicide formulation via leaf stomata , 1993 .

[128]  T. J. Cooke,et al.  The structure of plasmodesmata as revealed by plasmolysis, detergent extraction, and protease digestion , 1991, The Journal of cell biology.

[129]  D. Delmer,et al.  Determination of the Pore Size of Cell Walls of Living Plant Cells , 1979, Science.

[130]  U. Luttge Structure and Function of Plant Glands , 1971 .

[131]  J. Baur,et al.  Effect of tobacco mosaic virus infection on glucose metabolism in Nicotiana tabacum var. Samsun. III. Investigation of hexosemonophosphate shunt enzymes and steroid concentration and biosynthesis. , 1967, Virology.

[132]  H. Beevers MALONIC ACID AS AN INHIBITOR OF MAIZE ROOT RESPIRATION. , 1952, Plant physiology.