Treatment decisions and the use of MEK inhibitors for children with neurofibromatosis type 1-related plexiform neurofibromas
暂无分享,去创建一个
[1] S. Steinberg,et al. Long-Term Safety and Efficacy of Selumetinib in Children with Neurofibromatosis Type 1 on a Phase 1/2 Trial for Inoperable Plexiform Neurofibromas. , 2023, Neuro-oncology.
[2] C. Lázaro,et al. ERN GENTURIS tumour surveillance guidelines for individuals with neurofibromatosis type 1 , 2023, EClinicalMedicine.
[3] T. Ågesen,et al. Clinical Characteristics and Management of Children and Adults with Neurofibromatosis Type 1 and Plexiform Neurofibromas in Denmark: A Nationwide Study , 2022, Oncology and Therapy.
[4] H. Koike,et al. Surgical Treatment and Complications of Deep-Seated Nodular Plexiform Neurofibromas Associated with Neurofibromatosis Type 1 , 2022, Journal of clinical medicine.
[5] M. Loh,et al. MEK Inhibitors for Neurofibromatosis Type 1 Manifestations: Clinical Evidence and Consensus. , 2022, Neuro-oncology.
[6] Michael Fisher,et al. Management of Neurofibromatosis Type 1-Associated Plexiform Neurofibromas. , 2022, Neuro-oncology.
[7] A. Hirbe,et al. Plexiform neurofibroma: shedding light on the investigational agents in clinical trials , 2021, Expert opinion on investigational drugs.
[8] S. Amin,et al. Epidemiological and clinical burden associated with plexiform neurofibromas in pediatric neurofibromatosis type-1 (NF-1): a systematic literature review , 2021, Neurological Sciences.
[9] M. Epelman,et al. Pelvic plexiform neurofibroma during bowel/bladder dysfunction in an NF1 pediatric patient: A case report , 2021, Urology Case Reports.
[10] Michael Fisher,et al. Revised diagnostic criteria for neurofibromatosis type 1 and Legius syndrome: an international consensus recommendation , 2021, Genetics in Medicine.
[11] S. Sen,et al. Natural History and Disease Burden of Neurofibromatosis Type 1 with Plexiform Neurofibromas: A Systematic Literature Review , 2021, Adolescent health, medicine and therapeutics.
[12] Jiang Liu,et al. FDA Approval Summary: Selumetinib for Plexiform Neurofibroma , 2021, Clinical Cancer Research.
[13] B. Korf,et al. NF106: A Neurofibromatosis Clinical Trials Consortium Phase II Trial of the MEK Inhibitor Mirdametinib (PD-0325901) in Adolescents and Adults With NF1-Related Plexiform Neurofibromas , 2021, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[14] Steven P. Angus,et al. Cabozantinib for neurofibromatosis type 1–related plexiform neurofibromas: a phase 2 trial , 2021, Nature Medicine.
[15] T. Lehky,et al. Safe marginal resection of atypical neurofibromas in neurofibromatosis type 1. , 2020, Journal of neurosurgery.
[16] S. Steinberg,et al. Selumetinib in Children with Inoperable Plexiform Neurofibromas. , 2020, The New England journal of medicine.
[17] K. Sarin,et al. Phenotypic heterogeneity of neurofibromatosis type 1 in a large international registry , 2020, JCI insight.
[18] B. Widemann,et al. Current status of MEK inhibitors in the treatment of plexiform neurofibromas , 2020, Child's Nervous System.
[19] T. Foiadelli,et al. Advanced pharmacological therapies for neurofibromatosis type 1-related tumors , 2020, Acta bio-medica : Atenei Parmensis.
[20] M. Krimmel,et al. Surgical management of peripheral nerve sheath tumours in children, with special consideration of neurofibromatoses , 2020, Child's Nervous System.
[21] G. Cerri,et al. Surgery combined with embolization in the treatment of plexiform neurofibroma: Case report and literature review , 2020, JAAD case reports.
[22] S. Steinberg,et al. Longitudinal evaluation of peripheral nerve sheath tumors in neurofibromatosis type 1: Growth analysis of plexiform neurofibromas and distinct nodular lesions. , 2020, Neuro-oncology.
[23] P. Wolkenstein,et al. Neurofibromatosis 1 French national guidelines based on an extensive literature review since 1966 , 2020, Orphanet journal of rare diseases.
[24] A. Chen,et al. The MEK inhibitor selumetinib reduces spinal neurofibroma burden in patients with NF1 and plexiform neurofibromas. , 2020, Neuro-oncology advances.
[25] A. Hirbe,et al. Diagnosis and management of malignant peripheral nerve sheath tumors: Current practice and future perspectives , 2019, Neuro-oncology advances.
[26] T. Rosenbaum,et al. Trametinib Induces Neurofibroma Shrinkage and Enables Surgery , 2019, Neuropediatrics.
[27] David T. Miller,et al. Health Supervision for Children With Neurofibromatosis Type 1 , 2019, Pediatrics.
[28] H. Terashi,et al. Two cases of debulking surgery for lower limb diffuse plexiform neurofibroma with transcatheter arterial embolisation , 2019, International journal of surgery case reports.
[29] S. Steinberg,et al. Association of plexiform neurofibroma volume changes and development of clinical morbidities in neurofibromatosis 1 , 2018, Neuro-oncology.
[30] S. Peltonen,et al. Prevalence of neurofibromatosis type 1 in the Finnish population , 2018, Genetics in Medicine.
[31] C. Lázaro,et al. 2016 Children's Tumor Foundation conference on neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis , 2018, American journal of medical genetics. Part A.
[32] K. Fjermestad,et al. Health Survey of Adults with Neurofibromatosis 1 Compared to Population Study Controls , 2018, Journal of Genetic Counseling.
[33] R. Friedrich,et al. Peripheral nerve sheath tumors of the upper extremity and hand in patients with neurofibromatosis type 1: topography of tumors and evaluation of surgical treatment in 62 patients , 2017, GMS Interdisciplinary plastic and reconstructive surgery DGPW.
[34] Kimberly J. Johnson,et al. Neurofibromatosis type 1 , 2017, Nature Reviews Disease Primers.
[35] N. Ratner,et al. Activity of Selumetinib in Neurofibromatosis Type 1-Related Plexiform Neurofibromas. , 2016, The New England journal of medicine.
[36] C. Marcus,et al. Sleep and pulmonary outcomes for clinical trials of airway plexiform neurofibromas in NF1 , 2016, Neurology.
[37] J. Blakeley,et al. Therapeutic advances for the tumors associated with neurofibromatosis type 1, type 2, and schwannomatosis. , 2016, Neuro-oncology.
[38] T. Vahlberg,et al. Incidence and mortality of neurofibromatosis: a total population study in Finland. , 2015, The Journal of investigative dermatology.
[39] M. Westphal,et al. Growth behavior of plexiform neurofibromas after surgery , 2013, Genetics in Medicine.
[40] T. Stinchcombe,et al. KRAS mutation: should we test for it, and does it matter? , 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[41] G. Page,et al. MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors. , 2013, The Journal of clinical investigation.
[42] C. Fox,et al. Perioperative management of neurofibromatosis type 1. , 2012, The Ochsner journal.
[43] Lisa J. Martin,et al. Pediatric plexiform neurofibromas: impact on morbidity and mortality in neurofibromatosis type 1. , 2012, The Journal of pediatrics.
[44] L. Kluwe,et al. Plexiform neurofibromas in children with neurofibromatosis type 1: frequency and associated clinical deficits. , 2011, The Journal of pediatrics.
[45] F. Canavese,et al. Resection of Plexiform Neurofibromas in Children With Neurofibromatosis Type 1 , 2011, Journal of pediatric orthopedics.
[46] L. Mariani,et al. Non-metastatic unresected paediatric non-rhabdomyosarcoma soft tissue sarcomas: results of a pooled analysis from United States and European groups. , 2011, European journal of cancer.
[47] Paul D. Smith,et al. The First-in-Human Study of the Hydrogen Sulfate (Hyd-Sulfate) Capsule of the MEK1/2 Inhibitor AZD6244 (ARRY-142886): A Phase I Open-Label Multicenter Trial in Patients with Advanced Cancer , 2010, Clinical Cancer Research.
[48] S. Huson,et al. Birth incidence and prevalence of tumor‐prone syndromes: Estimates from a UK family genetic register service , 2010, American journal of medical genetics. Part A.
[49] G. Hutchins,et al. Nf1-Dependent Tumors Require a Microenvironment Containing Nf1 +/−- and c-kit-Dependent Bone Marrow , 2008, Cell.
[50] D. Clapp,et al. Nf1+/- mice have increased neointima formation via hyperactivation of a Gleevec sensitive molecular pathway. , 2008, Human molecular genetics.
[51] Jan M Friedman,et al. Assessment of benign tumor burden by whole-body MRI in patients with neurofibromatosis 1. , 2008, Neuro-oncology.
[52] Paul D. Martin,et al. AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in preclinical models , 2007, Molecular Cancer Therapeutics.
[53] S. Steinberg,et al. NF1 plexiform neurofibroma growth rate by volumetric MRI , 2007, Neurology.
[54] L. Parada,et al. Nf1+/- mast cells induce neurofibroma like phenotypes through secreted TGF-beta signaling. , 2006, Human molecular genetics.
[55] J. Tonsgard. Clinical manifestations and management of neurofibromatosis type 1. , 2006, Seminars in pediatric neurology.
[56] I. Jacobs,et al. Management of head and neck plexiform neurofibromas in pediatric patients with neurofibromatosis type 1. , 2005, Archives of otolaryngology--head & neck surgery.
[57] D. Evans,et al. Malignant peripheral nerve sheath tumours in neurofibromatosis 1 , 2002, Journal of medical genetics.
[58] Q. Yang,et al. Mortality in neurofibromatosis 1: an analysis using U.S. death certificates. , 2001, American journal of human genetics.
[59] T. Matsuishi,et al. Mutation analysis of the methyl-CpG binding protein 2 gene (MECP2) in patients with Rett syndrome , 2000, Journal of medical genetics.
[60] E. Zackai,et al. Prognostic signs in the surgical management of plexiform neurofibroma: the Children's Hospital of Philadelphia experience, 1974-1994. , 1997, The Journal of pediatrics.
[61] OUP accepted manuscript , 2022, Neuro-Oncology.
[62] R. Friedrich,et al. Surgery for Peripheral Nerve Sheath Tumours of the Buttocks, Legs and Feet in 90 Patients With Neurofibromatosis Type 1 , 2021, In Vivo.
[63] B. Widemann,et al. Orbital/Periorbital Plexiform Neurofibromas in Children with Neurofibromatosis Type 1: Multidisciplinary Recommendations for Care. , 2017, Ophthalmology.
[64] Jan M Friedman,et al. Prevalence of neurofibromatosis 1 in German children at elementary school enrollment. , 2005, Archives of dermatology.
[65] Hilde van der Togt,et al. Publisher's Note , 2003, J. Netw. Comput. Appl..
[66] David A. Williams,et al. Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/- mast cells. , 2003, The Journal of clinical investigation.