An ALS-associated mutation in the FUS 3′-UTR disrupts a microRNA–FUS regulatory circuitry

[1]  Y. Xi,et al.  MiR-200, a new star miRNA in human cancer. , 2014, Cancer letters.

[2]  Alessandro Fatica,et al.  A Feedforward Regulatory Loop between HuR and the Long Noncoding RNA linc-MD1 Controls Early Phases of Myogenesis , 2014, Molecular cell.

[3]  P. Rossini,et al.  Mutations in the 3' untranslated region of FUS causing FUS overexpression are associated with amyotrophic lateral sclerosis. , 2013, Human molecular genetics.

[4]  I. Bozzoni,et al.  TDP-43 Regulates the Microprocessor Complex Activity During In Vitro Neuronal Differentiation , 2013, Molecular Neurobiology.

[5]  G. Hicks,et al.  ALS-Associated FUS Mutations Result in Compromised FUS Alternative Splicing and Autoregulation , 2013, PLoS genetics.

[6]  Wim Robberecht,et al.  The changing scene of amyotrophic lateral sclerosis , 2013, Nature Reviews Neuroscience.

[7]  I. Bozzoni,et al.  FUS stimulates microRNA biogenesis by facilitating co‐transcriptional Drosha recruitment , 2012, The EMBO journal.

[8]  Emmette R. Hutchison,et al.  Interrogation of brain miRNA and mRNA expression profiles reveals a molecular regulatory network that is perturbed by mutant huntingtin , 2012, Journal of neurochemistry.

[9]  T. Hortobágyi,et al.  Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion , 2012, Acta Neuropathologica.

[10]  Gene W. Yeo,et al.  Misregulated RNA processing in amyotrophic lateral sclerosis , 2012, Brain Research.

[11]  H. Bussemaker,et al.  TLS/FUS (translocated in liposarcoma/fused in sarcoma) regulates target gene transcription via single-stranded DNA response elements , 2012, Proceedings of the National Academy of Sciences.

[12]  F. Fiesel,et al.  TDP‐43 and FUS/TLS: cellular functions and implications for neurodegeneration , 2011, The FEBS journal.

[13]  A. Rustgi,et al.  The role of the miR-200 family in epithelial-mesenchymal transition , 2010, Cancer biology & therapy.

[14]  I. Bozzoni,et al.  A minicircuitry involving REST and CREB controls miR-9-2 expression during human neuronal differentiation , 2010, Nucleic acids research.

[15]  D. Cleveland,et al.  TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration. , 2010, Human molecular genetics.

[16]  D. Cacchiarelli,et al.  Coupled RNA Processing and Transcription of Intergenic Primary MicroRNAs , 2009, Molecular and Cellular Biology.

[17]  Xun Hu,et al.  Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6 , 2009, Science.

[18]  M. Pericak-Vance,et al.  Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis , 2009, Science.

[19]  C. Burge,et al.  Most mammalian mRNAs are conserved targets of microRNAs. , 2008, Genome research.

[20]  M. F. Shannon,et al.  A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. , 2008, Cancer research.

[21]  T. Brabletz,et al.  A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells , 2008, EMBO reports.

[22]  Sun-Mi Park,et al.  The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. , 2008, Genes & development.

[23]  K. Gunsalus,et al.  Combinatorial microRNA target predictions , 2005, Nature Genetics.

[24]  G. Hicks,et al.  The RNA Binding Protein TLS Is Translocated to Dendritic Spines by mGluR5 Activation and Regulates Spine Morphology , 2005, Current Biology.

[25]  R. Shiekhattar,et al.  The Microprocessor complex mediates the genesis of microRNAs , 2004, Nature.

[26]  I. Bozzoni,et al.  A new vector, based on the PolII promoter of the U1 snRNA gene, for the expression of siRNAs in mammalian cells. , 2004, Molecular therapy : the journal of the American Society of Gene Therapy.

[27]  J. C. James,et al.  Quantitative assessment of gene targeting in vitro and in vivo by the pancreatic transcription factor, Pdx1. Importance of chromatin structure in directing promoter binding. , 2002, The Journal of biological chemistry.

[28]  H. Ruley,et al.  Fus deficiency in mice results in defective B-lymphocyte development and activation, high levels of chromosomal instability and perinatal death , 2000, Nature Genetics.

[29]  R. Kurokawa,et al.  Promoter-associated noncoding RNA from the CCND1 promoter. , 2012, Methods in molecular biology.

[30]  A. Roses,et al.  Identification of miRNA Changes in Alzheimer's Disease Brain and CSF Yields Putative Biomarkers and Insights into Disease Pathways , 2008 .

[31]  V. Kim,et al.  In vitro and in vivo assays for the activity of Drosha complex. , 2007, Methods in enzymology.