Analysis of the functional role of cGMP-dependent protein kinase in intact human platelets using a specific activator 8-para-chlorophenylthio-cGMP.

[1]  U. Walter,et al.  Role of cGMP and cGMP-dependent protein kinase in nitrovasodilator inhibition of agonist-evoked calcium elevation in human platelets. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[2]  U. Walter,et al.  Characterization of Sp-5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole- 3',5'-monophosphorothioate (Sp-5,6-DCl-cBiMPS) as a potent and specific activator of cyclic-AMP-dependent protein kinase in cell extracts and intact cells. , 1991, The Biochemical journal.

[3]  U. Walter,et al.  Endothelial cell-dependent phosphorylation of a platelet protein mediated by cAMP- and cGMP-elevating factors. , 1991, The Journal of biological chemistry.

[4]  S. Moncada,et al.  Nitric oxide: physiology, pathophysiology, and pharmacology. , 1991, Pharmacological reviews.

[5]  U. Kaupp The cyclic nucleotide-gated channels of vertebrate photoreceptors and olfactory epithelium , 1991, Trends in Neurosciences.

[6]  R. Haslam,et al.  Effects of Nitrovasodilators on Platelet Cyclic Nucleotide Levels in Rabbit Blood; Role for Cyclic AMP in Synergistic Inhibition of Platelet Function by SIN‐1 and Prostaglandin E1 , 1991, Journal of cardiovascular pharmacology.

[7]  J. Loscalzo,et al.  Inhibition of fibrinogen binding to human platelets by S-nitroso-N-acetylcysteine. , 1990, The Journal of biological chemistry.

[8]  R. Colman,et al.  Purification and characterization of a cyclic GMP-stimulated cyclic nucleotide phosphodiesterase from the cytosol of human platelets. , 1990, Thrombosis research.

[9]  R. Haslam,et al.  Molecular basis of the synergistic inhibition of platelet function by nitrovasodilators and activators of adenylate cyclase: inhibition of cyclic AMP breakdown by cyclic GMP. , 1990, Molecular pharmacology.

[10]  B. Jastorff,et al.  Inhibition of cGMP‐dependent protein kinase by (Rp)‐guanosine 3',5'‐monophosphorothioates , 1990, FEBS letters.

[11]  U. Walter,et al.  Stoichiometric and reversible phosphorylation of a 46-kDa protein in human platelets in response to cGMP- and cAMP-elevating vasodilators. , 1990, The Journal of biological chemistry.

[12]  J. Beavo,et al.  Inhibition and stimulation of photoreceptor phosphodiesterases by dipyridamole and M&B 22,948. , 1989, Molecular pharmacology.

[13]  U. Walter,et al.  Purification of a vasodilator-regulated phosphoprotein from human platelets. , 1989, European journal of biochemistry.

[14]  B. Jastorff,et al.  Synthesis of the 3′,5′-Cyclic Phosphates from Unprotected Nucleosides , 1989 .

[15]  J. Corbin,et al.  Relaxation of vascular and tracheal smooth muscle by cyclic nucleotide analogs that preferentially activate purified cGMP-dependent protein kinase. , 1988, Molecular pharmacology.

[16]  J. Beavo,et al.  Phosphorylation results in activation of a cAMP phosphodiesterase in human platelets. , 1988, The Journal of biological chemistry.

[17]  U. Walter,et al.  Vasodilator-stimulated protein phosphorylation in platelets is mediated by cAMP- and cGMP-dependent protein kinases. , 1987, European journal of biochemistry.

[18]  K. Jakobs,et al.  Demonstration of cGMP-dependent protein kinase and cGMP-dependent phosphorylation in cell-free extracts of platelets. , 1986, European journal of biochemistry.

[19]  J. Beavo,et al.  Isolation and characterization of bovine cardiac muscle cGMP-inhibited phosphodiesterase: a receptor for new cardiotonic drugs. , 1986, Molecular pharmacology.

[20]  D. Øgreid,et al.  Studies of cGMP analog specificity and function of the two intrasubunit binding sites of cGMP-dependent protein kinase. , 1986, The Journal of biological chemistry.

[21]  J. Gardner Mechanism by which dibutyryl cyclic guanosine monophosphate antagonizes the action of cholecystokinin. , 1983, Gastroenterology.

[22]  P. Greengard,et al.  Microinjection of catalytic subunit of cyclic AMP-dependent protein kinase enhances calcium action potentials of bag cell neurons in cell culture. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[23]  P. Greengard,et al.  Immunological distinction between guanosine 3':5'-monophosphate-dependent and adenosine 3':5'-monophosphate-dependent protein kinases. , 1980, The Journal of biological chemistry.

[24]  P. de Neef,et al.  Butyryl derivatives of cyclic GMP interfere with the biological and the immunological properties of the pancreozymin-gastrin family of peptides. , 1980, Molecular pharmacology.

[25]  S. Peikin,et al.  Actions of derivatives of cyclic nucleotides on dispersed acini from guinea pig pancreas. Discovery of a competitive antagonist of the action of cholecystokinin. , 1979, The Journal of biological chemistry.

[26]  R. K. Robins,et al.  Synthesis and biochemical studies of various 8-substituted derivatives of guanosine 3',5'-cyclic phosphate, inosine 3',5'-cyclic phosphate, and xanthosine 3',5'-cyclic phosphate. , 1973, Biochemistry.

[27]  U Walter,et al.  Physiological role of cGMP and cGMP-dependent protein kinase in the cardiovascular system. , 1989, Reviews of physiology, biochemistry and pharmacology.

[28]  B. Jastorff,et al.  [15] cAMP analog antagonists of cAMP action , 1988 .

[29]  Beavo Ja Multiple isozymes of cyclic nucleotide phosphodiesterase. , 1988 .

[30]  P. Hamet,et al.  [64] Platelet cGMP-binding phosphodiesterase , 1988 .

[31]  J. Corbin,et al.  3 Cyclic Nucleotide-Dependent Protein Kinases , 1986 .

[32]  B. Jastorff,et al.  Physico-chemical characterization of cyclic nucleotides by reversed-phase high-performance liquid chromatography , 1985 .

[33]  B. Jastorff,et al.  Physico-chemical characterization of cyclic nucleotides by reversed-phase high-performance liquid chromatography: II. Quantitative determination of hydrophobicity , 1985 .

[34]  U. Walter Cyclic-GMP-regulated enzymes and their possible physiological functions. , 1984, Advances in cyclic nucleotide and protein phosphorylation research.

[35]  R. Roskoski [1] Assays of protein kinase , 1983 .