Anion cascade reactions III: Synthesis of 3-isoquinuclidone bridged polycyclic lactams
暂无分享,去创建一个
[1] Alexandre Audic,et al. Synthesis of the CDF Ring System of Hexacyclinic Acid , 2022, Synthesis.
[2] Ming‐Hua Zeng,et al. CuBr-promoted domino Biginelli reaction for the diastereoselective synthesis of bridged polyheterocycles: mechanism studies and in vitro anti-tumor activities , 2022, Chinese Chemical Letters.
[3] Xiongwei Jiang,et al. Iron-catalyzed hydroaminocarbonylation of alkynes: Selective and efficient synthesis of primary α,β-unsaturated amides , 2022, Chinese Chemical Letters.
[4] Hanmin Huang,et al. Palladium-Catalyzed Tandem Hydrocarbonylative Lactamization and Cycloaddition Reaction for the Construction of Bridged Polycyclic Lactams. , 2021, Organic letters.
[5] Youyoung Kim,et al. Biopatterned Reorganization of Alkaloids Enabled by Ring-Opening Functionalization of Tertiary Amines. , 2021, Journal of the American Chemical Society.
[6] Wei Chen,et al. High-Temperature Switchable Nonlinear Optical and Dielectric Material Revealed by Molecular Modification , 2021 .
[7] Jun Jiang,et al. Electrosynthesis of 1-indanones , 2021 .
[8] Ying-Wu Lin,et al. Visible-light-initiated tandem synthesis of difluoromethylated oxindoles in 2-MeTHF under additive-, metal catalyst-, external photosensitizer-free and mild conditions , 2021, Chinese Chemical Letters.
[9] Guisheng Zhang,et al. Nickel-catalyzed deaminative Sonogashira coupling of alkylpyridinium salts enabled by NN2 pincer ligand , 2020, Nature Communications.
[10] Wei Wei,et al. Catalyst- and additive-free selective sulfonylation/cyclization of 1,6-enynes with arylazo sulfones leading to sulfonylated γ-butyrolactams , 2020 .
[11] Shasha Zhang,et al. Modular Synthesis of Drimane Meroterpenoids Leveraging Decarboxylative Borylation and Suzuki Coupling. , 2020, Organic letters.
[12] Gang Zhao,et al. Organophosphine bearing multiple hydrogen-bond donors for asymmetric Michael addition reaction of 1-oxoindane-2-carboxylic acid ester via dual-reagent catalysis , 2020 .
[13] Gong Chen,et al. Selective Removal of Aminoquinoline Auxiliary by IBX Oxidation. , 2019, The Journal of organic chemistry.
[14] X. Liu,et al. Discovery of ( E)- N1-(3-Fluorophenyl)- N3-(3-(2-(pyridin-2-yl)vinyl)-1 H-indazol-6-yl)malonamide (CHMFL-KIT-033) as a Novel c-KIT T670I Mutant Selective Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs). , 2019, Journal of medicinal chemistry.
[15] Sunkyu Han,et al. Biosynthetically Inspired Transformation of Iboga to Monomeric Post-iboga Alkaloids , 2019, Chem.
[16] Xin Hong,et al. Computational studies of cinchona alkaloid-catalyzed asymmetric Michael additions , 2018, Chinese Chemical Letters.
[17] Haifeng Yu,et al. Copper-Catalysed (Diacetoxyiodo)benzene-Promoted Aerobic Esterification Reaction: Synthesis of Oxamates from Acetoacetamides , 2018, Advanced Synthesis & Catalysis.
[18] C. So,et al. Palladium-Catalyzed Direct Arylation of Polyfluoroarenes for Accessing Tetra- ortho-Substituted Biaryls: Buchwald-type Ligand Having Complementary -PPh2 Moiety Exhibits Better Efficiency. , 2018, The Journal of organic chemistry.
[19] K. Mineev,et al. DNA sequence-specific ligands. XVII. Synthesis, spectral properties, virological and biochemical studies of fluorescent dimeric bisbenzimidazoles DBA(n). , 2018, Bioorganic & medicinal chemistry.
[20] Yameng Wan,et al. Selective Cleavage of Inert Aryl C-N Bonds in N-Aryl Amides. , 2018, The Journal of organic chemistry.
[21] David R. Spring,et al. A fragment-based approach leading to the discovery of a novel binding site and the selective CK2 inhibitor CAM4066 , 2017, Bioorganic & medicinal chemistry.
[22] Yi‐Xia Jia,et al. Enantioselective Dearomative Difunctionalization of Indoles by Palladium-Catalyzed Heck/Sonogashira Sequence. , 2017, Angewandte Chemie.
[23] Y. Lian,et al. Construction of 1-Heteroaryl-3-azabicyclo[3.1.0]hexanes by sp3-sp2 Suzuki-Miyaura and Chan-Evans-Lam Coupling Reactions of Tertiary Trifluoroborates. , 2017, Organic letters.
[24] Yong Zhang,et al. Bio-Catalytic Bis-Michael Reaction for Generating Cyclohexanones with a Quaternary Carbon Center Using Glucoamylase , 2017, Catalysis Letters.
[25] Guigen Li,et al. High-Valent Palladium-Promoted Formal Wagner-Meerwein Rearrangement. , 2016, Organic letters.
[26] G. Posner,et al. Highly regiocontrolled and stereocontrolled syntheses of polysubstituted aminocyclohexanes: mild inverse-electron-demand Diels–Alder cycloadditions of electrophilic 2-pyridones , 2016 .
[27] D. Boger,et al. Synthesis of a Potent Vinblastine: Rationally Designed Added Benign Complexity. , 2016, Journal of the American Chemical Society.
[28] Xingang Xie,et al. Bioinspired Collective Syntheses of Iboga-Type Indole Alkaloids. , 2016, Organic letters.
[29] A. Rahman,et al. A concise synthesis and evaluation of new malonamide derivatives as potential α-glucosidase inhibitors. , 2016, Bioorganic & medicinal chemistry.
[30] J. Bajorath,et al. Limiting the Number of Potential Binding Modes by Introducing Symmetry into Ligands: Structure-Based Design of Inhibitors for Trypsin-Like Serine Proteases. , 2016, Chemistry.
[31] Xianxiu Xu,et al. Diastereoselective Synthesis of 3,4-Benzomorphan Derivatives via Tandem [5 + 1]/Hemiaminalization of (2-Aminoaryl)divinyl Ketones. , 2016, Organic letters.
[32] E. V. D. Eycken,et al. Regio‐ and Chemoselective Formation of Spiroindolinone–Isoindolinone by a Palladium‐Catalyzed Buchwald–Hartwig Addition–Elimination Sequence , 2014 .
[33] E. V. Van der Eycken,et al. Facile access to functionalized spiro[indoline-3,2'-pyrrole]-2,5'-diones via post-Ugi domino Buchwald-Hartwig/Michael reaction. , 2014, Organic letters.
[34] J. Khurana,et al. An efficient catalyst free synthesis of nitrogen containing spiro heterocycles via [5 + 1] double Michael addition reaction , 2014 .
[35] C. Johannes,et al. Expedient synthesis of bicyclo[3.2.1]octanes and bicyclo[3.3.1]nonanes via the double Michael addition to cyclic dienones , 2013 .
[36] J. Aubé,et al. Chemistry of bridged lactams and related heterocycles. , 2013, Chemical reviews.
[37] Manuela Weber,et al. Catalytic asymmetric synthesis of spirocyclic azlactones by a double Michael-addition approach. , 2013, Chemistry.
[38] P. Slepukhin,et al. Synthesis of 6-Acetyl-1-methyl-3-oxo-5,8-diphenyl-2-azabicyclo[2.2.2]octane-4-carbonitrile , 2013, Chemistry of Heterocyclic Compounds.
[39] S. Ji,et al. Palladium-catalyzed carbonylative Sonogashira coupling of aryl bromides via tert-butyl isocyanide insertion. , 2013, The Journal of organic chemistry.
[40] C. Nájera,et al. Recent advances in Sonogashira reactions. , 2011, Chemical Society reviews.
[41] Fu‐She Han,et al. A Highly Practical and Reliable Nickel Catalyst for Suzuki–Miyaura Coupling of Aryl Halides , 2011 .
[42] M. Yan,et al. Organocatalytic conjugate addition of malononitrile to conformationally restricted dienones. , 2011, The Journal of organic chemistry.
[43] Bin Wu,et al. Efficient synthesis of optically active 4-nitro-cyclohexanones via bifunctional thiourea-base catalyzed double-Michael addition of nitromethane to dienones. , 2011, Chemical communications.
[44] J. Cuthbertson,et al. A Tandem Amination/LactamisationRoute to 2-Azabicyclo[2.2.2]octanones , 2010 .
[45] Dawei Zhang,et al. Direct Stereoselective Synthesisof 1-Amino-2,5-diarylcyclohexanecarboxylic Acid Derivatives Basedon a [5+1] Annulation of Divinyl Ketoneand Isocyanoacetate , 2010 .
[46] A. Macleod,et al. Identification of potent and selective VEGFR receptor tyrosine kinase inhibitors having new amide isostere headgroups. , 2010, Bioorganic & medicinal chemistry letters.
[47] T. Nakano,et al. Design, synthesis, and biological activity of boronic acid-based histone deacetylase inhibitors. , 2009, Journal of medicinal chemistry.
[48] Qun Liu,et al. Tandem double-Michael-addition/cyclization/acyl migration of 1,4-dien-3-ones and ethyl isocyanoacetate: stereoselective synthesis of pyrrolizidines. , 2009, Angewandte Chemie.
[49] J. Aubé,et al. Stability of medium-bridged twisted amides in aqueous solutions. , 2009, The Journal of organic chemistry.
[50] Y. V. Reddy,et al. Double cascade reactions based on the Barbas dienamine platform: highly stereoselective synthesis of functionalized cyclohexanes for cardiovascular agents. , 2008, Organic & biomolecular chemistry.
[51] Jeffrey L. Cross,et al. Concise construction of novel bridged bicyclic lactams by sequenced Ugi/RCM/Heck reactions. , 2007, Organic letters.
[52] Guido Galley,et al. Novel orally active, dibenzazepinone-based γ-secretase inhibitors , 2007 .
[53] M. Pudlo,et al. First Suzuki-Miyaura type cross-coupling of ortho-azidobromobenzene with arylboronic acids and its application to the synthesis of fused aromatic indole-heterocycles , 2007 .
[54] A. Khorshidi,et al. RuIII-catalyzed double-conjugate 1,4-addition of indoles to symmetric enones , 2007 .
[55] C. Nájera,et al. The Sonogashira reaction: a booming methodology in synthetic organic chemistry. , 2007, Chemical reviews.
[56] J. Clayden,et al. The twisted amide 2-quinuclidone: 60 years in the making. , 2006, Angewandte Chemie.
[57] C. Cativiela,et al. Efficient synthesis of a new pipecolic acid analogue with a bicyclic structure , 2006 .
[58] Ji-tai Li,et al. Synthesis of 1,1-disubstituted-2,6-diarylcyclohexane-4-ones catalyzed by KF/basic Al2O3 under ultrasound. , 2005, Ultrasonics sonochemistry.
[59] M. O. Khan,et al. Solution-Phase Parallel Synthesis of N,6-Disubstituted Isoquinuclidines as Ibogaine Analogs , 2005 .
[60] M. Coutlangus,et al. On the Stereochemistry of Diaryl-Substituted Cyclohexanones Formed by Michael Reactions. Trans to Cis Isomerization of Their Ketals under Basic Conditions , 1998 .
[61] S. Handy,et al. Lithium Trifluoromethanesulfonimide in Acetone or Diethyl Ether as a Safe Alternative to Lithium Perchlorate in Diethyl Ether for Effecting Diels-Alder Reactions. Unexpected Influence of the Counterion of Exo/Endo Selectivity , 1995 .
[62] V. Padmavathi,et al. SYNTHESIS OF SOME SPIRO-ISOXAZOLIDINE-3,5-DIONES , 1992 .
[63] H. Hall,et al. Anti-Bredt bridgehead nitrogen compounds in ring-opening polymerization , 1983 .
[64] H. Inoue,et al. Azabicycloalkanes as analgetics. V. 4-Phenyl-2-azabicyclo[2,2,2]octanes. , 1976, Chemical & pharmaceutical bulletin.
[65] D. Alkalay,et al. New bicyclic enamines and iminium salts. II. Synthesis of 1,4-dihydro-1,4-ethanoisoquinolinium salts and 4,5-dihydro-1H-1,4-methano-3-benzazepinium salts by reaction of bridged lactams with organometallic reagents , 1971 .
[66] S. Ricca,et al. The Alkaloids of Tabernanthe Iboga. VII.1 Derivatives of Isoquinuclidine , 1958 .
[67] Yunhe Xu,et al. Palladium-Catalyzed Tandem Heck Cyclization Reactions to Access the Bridged N-Heterocyclic Compounds , 2021, Chinese Journal of Organic Chemistry.
[68] D. Zheng,et al. Hypervalent Organoiodine Promoted Dearylation Reaction of N-Aryl Sulfonamides , 2020, Chinese Journal of Organic Chemistry.
[69] Lin He,et al. N-Heterocyclic Carbene-Catalyzed Double Michael Addition of Cyano Acetates and Dienones: Diastereoselective Synthesis of Multisubstituted Cyclohexanones and Indanes , 2020, Chinese Journal of Organic Chemistry.
[70] Xiaowei Li,et al. Synthesis of Imidazolium Precursors for the Hydroxyl-Group-Modified N-Heterocyclic Carbenes and Applications of the in situ Generated Carbene Ligands in Suzuki-Miyaura and Sonogashira Coupling Reactions , 2017 .
[71] 陈杰,et al. 不对称有机催化Michael加成/半缩醛胺化/酰亚胺正离子环化串联反应研究进展 , 2013 .
[72] Mazin Nadhim Mousa Al Ugla. SYNTHSIS , CHARACTERIZATION AND EVALUATION OF TOPICAL ANTI-INFLAMATORY ACTIVITY OF DIMETHYL 4-OXO-2 , 6-DIPHENYLCYCLOHEXANE-1 , 1-DICARBOXYLATE , 2011 .
[73] C. Herdeis,et al. A Facile Entry to the 2-Azabicyclo[2.2.2]octane-6-one Skeleton via [4+2]-Cycloaddition , 1988 .
[74] B. Gill,et al. Structures of Marvel's .delta.-lactone and polymer , 1988 .