Understanding the IL-23-IL-17 immune pathway.
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[1] E. Venkatraman,et al. A phase I study evaluating the safety and pharmacokinetics of weekly paclitaxel and carboplatin in relapsed ovarian cancer , 2006, International Journal of Gynecologic Cancer.
[2] J. Stockman. Anti-Interleukin-12 Antibody for Active Crohn's Disease , 2006 .
[3] Ying Wang,et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17 , 2005, Nature Immunology.
[4] R. D. Hatton,et al. Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages , 2005, Nature Immunology.
[5] J. Shellito,et al. Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae , 2005, The Journal of experimental medicine.
[6] S. Khader,et al. IL-23 Compensates for the Absence of IL-12p70 and Is Essential for the IL-17 Response during Tuberculosis but Is Dispensable for Protection and Antigen-Specific IFN-γ Responses if IL-12p70 Is Available1 , 2005, The Journal of Immunology.
[7] M. Freudenberg,et al. IL-12 family members: differential kinetics of their TLR4-mediated induction by Salmonella enteritidis and the impact of IL-10 in bone marrow-derived macrophages. , 2005, International immunology.
[8] W. Aird,et al. CpG oligodeoxynucleotide protection in polymicrobial sepsis is dependent on interleukin-17. , 2005, The Journal of infectious diseases.
[9] P. Mastrantonio,et al. Bordetella pertussis-Infected Human Monocyte-Derived Dendritic Cells Undergo Maturation and Induce Th1 Polarization and Interleukin-23 Expression , 2005, Infection and Immunity.
[10] K. Ley,et al. Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17. , 2005, Immunity.
[11] J. Cebon,et al. Extracellular nucleotide signaling by P2 receptors inhibits IL-12 and enhances IL-23 expression in human dendritic cells: a novel role for the cAMP pathway. , 2005, Blood.
[12] T. Mcclanahan,et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation , 2005, The Journal of experimental medicine.
[13] A. Gottlieb,et al. A phase I study evaluating the safety, pharmacokinetics, and clinical response of a human IL-12 p40 antibody in subjects with plaque psoriasis. , 2004, The Journal of investigative dermatology.
[14] M. Neurath,et al. Anti-interleukin-12 antibody for active Crohn's disease. , 2004, The New England journal of medicine.
[15] A. Lovett-racke,et al. Silencing T-bet defines a critical role in the differentiation of autoreactive T lymphocytes. , 2004, Immunity.
[16] A. Lindén,et al. Interleukin-17 family members and inflammation. , 2004, Immunity.
[17] R. Kastelein,et al. IL-23 Provides a Limited Mechanism of Resistance to Acute Toxoplasmosis in the Absence of IL-121 , 2004, The Journal of Immunology.
[18] D. Ganea,et al. Prostaglandin E2 induces IL‐23 production in bone marrow‐derived dendritic cells , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[19] S. Szabo,et al. Loss of T-bet, But Not STAT1, Prevents the Development of Experimental Autoimmune Encephalomyelitis , 2004, The Journal of experimental medicine.
[20] I. Julkunen,et al. Streptococcus pyogenes and Lactobacillus rhamnosus differentially induce maturation and production of Th1‐type cytokines and chemokines in human monocyte‐derived dendritic cells , 2004, Journal of leukocyte biology.
[21] H. Smits,et al. Commensal Gram‐negative bacteria prime human dendritic cells for enhanced IL‐23 and IL‐27 expression and enhanced Th1 development , 2004, European journal of immunology.
[22] Matthijs Kramer,et al. Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[23] M. Dhodapkar,et al. Increased Expression of Interleukin 23 p19 and p40 in Lesional Skin of Patients with Psoriasis Vulgaris , 2004, The Journal of experimental medicine.
[24] Jiawen Li,et al. The expression of interleukin-17, interferon-gamma, and macrophage inflammatory protein-3 alpha mRNA in patients with psoriasis vulgaris. , 2004, Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.
[25] T. Mcclanahan,et al. Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation , 2003, The Journal of experimental medicine.
[26] M. Neurath,et al. Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells. , 2003, The Journal of clinical investigation.
[27] T. Luft,et al. Functional comparison of DCs generated in vivo with Flt3 ligand or in vitro from blood monocytes: differential regulation of function by specific classes of physiologic stimuli. , 2003, Blood.
[28] L. Glimcher,et al. T-bet is required for optimal production of IFN-γ and antigen-specific T cell activation by dendritic cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[29] J. Shellito,et al. Cutting Edge: Roles of Toll-Like Receptor 4 and IL-23 in IL-17 Expression in Response to Klebsiella pneumoniae Infection1 , 2003, The Journal of Immunology.
[30] P. Möller,et al. Colonic lamina propria dendritic cells in mice with CD4+ T cell‐induced colitis , 2003, European journal of immunology.
[31] V. Kelley,et al. IL-12 Deficiency in MRL-Faslpr Mice Delays Nephritis and Intrarenal IFN-γ Expression, and Diminishes Systemic Pathology1 , 2003, The Journal of Immunology.
[32] M. Kamoun,et al. Induction of Experimental Autoimmune Encephalomyelitis in IL-12 Receptor-β2-Deficient Mice: IL-12 Responsiveness Is Not Required in the Pathogenesis of Inflammatory Demyelination in the Central Nervous System1 , 2003, The Journal of Immunology.
[33] R. Kastelein,et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain , 2003, Nature.
[34] A. Gurney,et al. Interleukin-23 Promotes a Distinct CD4 T Cell Activation State Characterized by the Production of Interleukin-17* , 2003, The Journal of Biological Chemistry.
[35] A. Galy,et al. Increased production of pro-inflammatory cytokines and enhanced T cell responses after activation of human dendritic cells with IL-1 and CD40 ligand , 2002, BMC Immunology.
[36] Jianfei Yang,et al. T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells , 2002, Nature Immunology.
[37] S. Khoury,et al. Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis. , 2001, The Journal of clinical investigation.
[38] J. Reimann,et al. IL-12/IL-18-Dependent IFN-γ Release by Murine Dendritic Cells1 , 2001, The Journal of Immunology.
[39] P. Hertzog,et al. Differential Production of IL-12, IFN-α, and IFN-γ by Mouse Dendritic Cell Subsets1 , 2001, The Journal of Immunology.
[40] J. Reimann,et al. IL-12/IL-18-dependent IFN-gamma release by murine dendritic cells. , 2001, Journal of immunology.
[41] P. Hertzog,et al. Differential production of IL-12, IFN-alpha, and IFN-gamma by mouse dendritic cell subsets. , 2001, Journal of immunology.
[42] J Wagner,et al. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. , 2000, Immunity.
[43] A. Sher,et al. CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal. , 2000, Immunity.
[44] U. Grohmann,et al. Autocrine IL-12 is involved in dendritic cell modulation via CD40 ligation. , 1999, Journal of immunology.
[45] T. Martin,et al. IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. , 1999, The Journal of clinical investigation.
[46] P. Kivisäkk,et al. Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis , 1999, Multiple sclerosis.
[47] A. Schwarting,et al. IFN-gamma receptor signaling is essential for the initiation, acceleration, and destruction of autoimmune kidney disease in MRL-Fas(lpr) mice. , 1998, Journal of immunology.
[48] B. Ryffel,et al. IFN-γ Receptor Deletion Prevents Autoantibody Production and Glomerulonephritis in Lupus-Prone (NZB × NZW)F1 Mice , 1998, The Journal of Immunology.
[49] B. Ryffel,et al. IFN-gamma receptor deletion prevents autoantibody production and glomerulonephritis in lupus-prone (NZB x NZW)F1 mice. , 1998, Journal of immunology.
[50] D. Balomenos,et al. Interferon-gamma is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice. , 1998, The Journal of clinical investigation.
[51] C. Chan,et al. IFN-gamma-deficient mice develop experimental autoimmune uveitis in the context of a deviant effector response. , 1997, Journal of immunology.
[52] A. Billiau,et al. Accelerated collagen-induced arthritis in IFN-gamma receptor-deficient mice. , 1997, Journal of immunology.
[53] J. Moslehi,et al. Roles of interferon-gamma and interleukin-4 in murine lupus. , 1997, The Journal of clinical investigation.
[54] A. Lanzavecchia,et al. Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation , 1996, The Journal of experimental medicine.
[55] T. Owens,et al. Interferon‐γ confers resistance to experimental allergic encephalomyelitis , 1996, European journal of immunology.
[56] L. Steinman,et al. Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE). , 1996, Journal of immunology.
[57] F. Denizot,et al. CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene. , 1993, Journal of immunology.
[58] R. Coffman,et al. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. , 1989, Annual review of immunology.
[59] R. Coffman,et al. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. , 1986, Journal of immunology.
[60] D. Franchimont,et al. Crohn's Disease , 1976, The Lancet.
[61] I. Leodolter. [Crohn's disease]. , 1967, Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete.