A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma

[1]  J. Fitzgibbon,et al.  A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma , 2014, Genome Medicine.

[2]  N. Lemoine,et al.  Nuclear translocation of FGFR1 and FGF2 in pancreatic stellate cells facilitates pancreatic cancer cell invasion , 2014, EMBO molecular medicine.

[3]  C. Iacobuzio-Donahue,et al.  RhoC Interacts with Integrin α5β1 and Enhances Its Trafficking in Migrating Pancreatic Carcinoma Cells , 2013, PloS one.

[4]  J. Gautier,et al.  Cdc45 is a critical effector of myc-dependent DNA replication stress. , 2013, Cell reports.

[5]  Sean R. Davis,et al.  NCBI GEO: archive for functional genomics data sets—update , 2012, Nucleic Acids Res..

[6]  Lincoln D. Stein,et al.  Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes , 2012, Nature.

[7]  A. Perkins,et al.  The F‐BAR protein NOSTRIN participates in FGF signal transduction and vascular development , 2012, The EMBO journal.

[8]  W. Allum,et al.  Incidence and survival for hepatic, pancreatic and biliary cancers in England between 1998 and 2007. , 2012, Cancer epidemiology.

[9]  Steven J. M. Jones,et al.  Comprehensive molecular characterization of human colon and rectal cancer , 2012, Nature.

[10]  J. Godet,et al.  Integrin α5β1 plays a critical role in resistance to temozolomide by interfering with the p53 pathway in high-grade glioma. , 2012, Cancer research.

[11]  Steven J. M. Jones,et al.  Comprehensive molecular portraits of human breast tumors , 2012, Nature.

[12]  E. Nakakura,et al.  Pancreatic Adenocarcinoma, version 2.2012: featured updates to the NCCN Guidelines. , 2012, Journal of the National Comprehensive Cancer Network : JNCCN.

[13]  Michael Schroeder,et al.  Google Goes Cancer: Improving Outcome Prediction for Cancer Patients by Network-Based Ranking of Marker Genes , 2012, PLoS Comput. Biol..

[14]  L. Zentilin,et al.  Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in mice. , 2012, The Journal of clinical investigation.

[15]  F. Markowetz,et al.  The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups , 2012, Nature.

[16]  Yufeng Liu,et al.  R/DWD: distance-weighted discrimination for classification, visualization and batch adjustment , 2012, Bioinform..

[17]  Jochen Gaedcke,et al.  DPEP1 Inhibits Tumor Cell Invasiveness, Enhances Chemosensitivity and Predicts Clinical Outcome in Pancreatic Ductal Adenocarcinoma , 2012, PloS one.

[18]  Hong Wu,et al.  Integrative Survival-Based Molecular Profiling of Human Pancreatic Cancer , 2012, Clinical Cancer Research.

[19]  Tatsuhiko Tsunoda,et al.  High-Risk Ovarian Cancer Based on 126-Gene Expression Signature Is Uniquely Characterized by Downregulation of Antigen Presentation Pathway , 2012, Clinical Cancer Research.

[20]  Benjamin J. Raphael,et al.  Integrated Genomic Analyses of Ovarian Carcinoma , 2011, Nature.

[21]  P. Spellman,et al.  Subtypes of Pancreatic Ductal Adenocarcinoma and Their Differing Responses to Therapy , 2011, Nature Medicine.

[22]  Andrew Menzies,et al.  The patterns and dynamics of genomic instability in metastatic pancreatic cancer , 2010, Nature.

[23]  Igor Jurisica,et al.  Prognostic and predictive gene signature for adjuvant chemotherapy in resected non-small-cell lung cancer. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[24]  Marian Brennan,et al.  Integrins as therapeutic targets: lessons and opportunities , 2010, Nature Reviews Drug Discovery.

[25]  A. Harris,et al.  Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene , 2010, British Journal of Cancer.

[26]  A. Jemal,et al.  Cancer Statistics, 2010 , 2010, CA: a cancer journal for clinicians.

[27]  Judy M. Anderson,et al.  A Six-Gene Signature Predicts Survival of Patients with Localized Pancreatic Ductal Adenocarcinoma , 2010, PLoS medicine.

[28]  Nabil Wasif,et al.  Impact of Tumor Grade on Prognosis in Pancreatic Cancer: Should We Include Grade in AJCC Staging? , 2010, Annals of Surgical Oncology.

[29]  M. Manns,et al.  Molecular therapy of pancreatic cancer. , 2010, Minerva endocrinologica.

[30]  M. Moore,et al.  Advanced pancreatic carcinoma: current treatment and future challenges , 2010, Nature Reviews Clinical Oncology.

[31]  Krishna R. Kalari,et al.  FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt. , 2009, Cancer cell.

[32]  N. Lemoine,et al.  Pancreatic cancer: molecular pathogenesis and new therapeutic targets , 2009, Nature Reviews Gastroenterology &Hepatology.

[33]  J. Mosley,et al.  Intrinsic bias in breast cancer gene expression data sets , 2009, BMC Cancer.

[34]  Igor Jurisica,et al.  Prognostic gene signatures for non-small-cell lung cancer , 2009, Proceedings of the National Academy of Sciences.

[35]  Liviu Badea,et al.  Combined gene expression analysis of whole-tissue and microdissected pancreatic ductal adenocarcinoma identifies genes specifically overexpressed in tumor epithelia. , 2008, Hepato-gastroenterology.

[36]  G. Parmigiani,et al.  Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses , 2008, Science.

[37]  H. Friess,et al.  Association of axon guidance factor Semaphorin 3A with poor outcome in pancreatic cancer , 2007, International journal of cancer.

[38]  Yusuke Nakamura,et al.  Activation of KIF4A as a Prognostic Biomarker and Therapeutic Target for Lung Cancer , 2007, Clinical Cancer Research.

[39]  M. Mann,et al.  The human urinary proteome contains more than 1500 proteins, including a large proportion of membrane proteins , 2006, Genome Biology.

[40]  P. Febbo,et al.  Noise and bias in microarray analysis of tumor specimens. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[41]  Christian Pilarsky,et al.  Meta-analysis of microarray data on pancreatic cancer defines a set of commonly dysregulated genes , 2005, Oncogene.

[42]  C. Pilarsky,et al.  Gene expression profiling of microdissected pancreatic ductal carcinomas using high-density DNA microarrays. , 2004, Neoplasia.

[43]  Murray F. Brennan,et al.  Prognostic Nomogram for Patients Undergoing Resection for Adenocarcinoma of the Pancreas , 2004, Annals of surgery.

[44]  T. Veenstra,et al.  The Human Plasma Proteome , 2004, Molecular & Cellular Proteomics.

[45]  J. Diffley,et al.  DNA synthesis at individual replication forks requires the essential initiation factor Cdc45p , 2000, The EMBO journal.

[46]  Elliot K Fishman,et al.  Pancreatic ductal adenocarcinoma radiology reporting template: consensus statement of the Society of Abdominal Radiology and the American Pancreatic Association. , 2014, Radiology.

[47]  Steven J. M. Jones,et al.  Comprehensive molecular portraits of human breast tumours , 2013 .

[48]  D. Tuveson,et al.  Physiological analysis of oncogenic K-ras. , 2006, Methods in enzymology.