The epidemic of methylisothiazolinone: a European prospective study

The use of methylisothiazolinone (MI) in cosmetic products has caused an unprecedented epidemic of MI contact allergy. Current data concerning exposures at a European level are required.

[1]  C. Geisler,et al.  Cross‐reactivity between methylisothiazolinone, octylisothiazolinone and benzisothiazolinone using a modified local lymph node assay , 2017, The British journal of dermatology.

[2]  M. Bruze,et al.  Concomitant contact allergies to formaldehyde, methylchloroisothiazolinone/methylisothiazolinone, methylisothiazolinone, and fragrance mixes I and II , 2016, Contact dermatitis.

[3]  A. Giménez-Arnau Opinion of the Scientific Committee on Consumer safety (SCCS) - Opinion on the safety of the use of Methylisothiazolinone (MI) (P94), in cosmetic products (sensitisation only). , 2016, Regulatory toxicology and pharmacology : RTP.

[4]  I. Namer,et al.  In situ chemical behaviour of methylisothiazolinone (MI) and methylchloroisothiazolinone (MCI) in reconstructed human epidermis: a new approach to the cross‐reactivity issue , 2016, Contact dermatitis.

[5]  T. Agner,et al.  European Society of Contact Dermatitis guideline for diagnostic patch testing – recommendations on best practice , 2015, Contact dermatitis.

[6]  J. Thyssen,et al.  Failures in risk assessment and risk management for cosmetic preservatives in Europe and the impact on public health , 2015, Contact dermatitis.

[7]  C. Lidén,et al.  Methylisothiazolinone in rinse‐off products causes allergic contact dermatitis: a repeated open‐application study , 2015, The British journal of dermatology.

[8]  M. Carder,et al.  Methylchloroisothiazolinone and methylisothiazolinone contact allergy: an occupational perspective , 2015, Contact dermatitis.

[9]  M. Wilkinson,et al.  Contact allergy to methylisothiazolinone: Has there been any change? Experience of a UK centre , 2015, Contact dermatitis.

[10]  R. Pujol,et al.  Is methylisothiazolinone contact allergy a risk factor for polysensitization? , 2015, Contact dermatitis.

[11]  Incompetence and failure to regulate methylisothiazolinone , 2015, Contact dermatitis.

[12]  J. Geier,et al.  Concomitant reactivity to methylisothiazolinone, benzisothiazolinone, and octylisothiazolinone. International Network of Departments of Dermatology data, 2009–2013 , 2015, Contact dermatitis.

[13]  W. Uter,et al.  Methylisothiazolinone and benzisothiazolinone are widely used in paint: a multicentre study of paints from five European countries , 2015, Contact dermatitis.

[14]  J. Bonde,et al.  Isothiazolinones in commercial products at Danish workplaces , 2014, Contact dermatitis.

[15]  H. Lapeere,et al.  The dramatic increase in the rate of methylisothiazolinone contact allergy in Belgium: a multicentre study , 2014, Contact dermatitis.

[16]  R. Bossi,et al.  Emission of isothiazolinones from water-based paints. , 2014, Environmental science & technology.

[17]  B. Gruvberger,et al.  Patch testing with serial dilutions of various isothiazolinones in patients hypersensitive to methylchloroisothiazolinone/methylisothiazolinone , 2014, Contact dermatitis.

[18]  I. White,et al.  Presumed airborne contact allergy to methylisothiazolinone causing acute severe facial dermatitis and respiratory difficulty , 2014, Contact dermatitis.

[19]  N. Meyer,et al.  Outbreak of contact sensitization to methylisothiazolinone: an analysis of French data from the REVIDAL‐GERDA network , 2014, Contact dermatitis.

[20]  M. Gonçalo,et al.  Methylisothiazolinone: second ‘epidemic’ of isothiazolinone sensitization , 2014, Contact dermatitis.

[21]  G. Johnston The rise in prevalence of contact allergy to methylisothiazolinone in the British Isles , 2014, Contact dermatitis.

[22]  K. Andersen,et al.  Further evidence of the methylisothiazolinone epidemic , 2014, Contact dermatitis.

[23]  W. Uter,et al.  Coupled exposure to ingredients of cosmetic products: II. Preservatives , 2014, Contact dermatitis.

[24]  K. Alanko,et al.  An epidemic of contact allergy to methylisothiazolinone in Finland , 2014, Contact dermatitis.

[25]  J. Johansen,et al.  Methylisothiazolinone contact allergy – a growing epidemic , 2013, Contact dermatitis.

[26]  Wolfgang Uter,et al.  Risk factors associated with methylisothiazolinone contact sensitization , 2013, Contact dermatitis.

[27]  J. Johansen,et al.  Methylisothiazolinone in paint forces a patient out of her apartment , 2013, Contact dermatitis.

[28]  K. Andersen,et al.  Allergic contact dermatitis from octylisothiazolinone , 2013, Contact dermatitis.

[29]  M. Gonçalo,et al.  Whilst Rome Burns: The Epidemic of Contact Allergy to Methylisothiazolinone , 2013, Contact dermatitis.

[30]  H. Maibach,et al.  Patch testing with 2.0% (0.60 mg/cm2) formaldehyde instead of 1.0% (0.30 mg/cm2) detects significantly more contact allergy , 2013, Contact dermatitis.

[31]  J. Geier,et al.  Recent increase in allergic reactions to methylchloroisothiazolinone/methylisothiazolinone: is methylisothiazolinone the culprit? , 2012, Contact dermatitis.

[32]  B. L. Andersen,et al.  Occupational contact dermatitis in painters – an analysis of patch test data from the Danish Contact Dermatitis Group , 2012, Contact dermatitis.

[33]  J. Thyssen,et al.  Presumed primary contact sensitization to methylisothiazolinone from paint: a chemical that became airborne , 2012, Contact dermatitis.

[34]  C. Lidén,et al.  Preservatives and fragrances in selected consumer‐available cosmetics and detergents , 2011, Contact dermatitis.

[35]  A. Goossens,et al.  Methylisothiazolinone, an emerging allergen in cosmetics? , 2010, Contact dermatitis.

[36]  B. Gruvberger,et al.  Cross‐reactivity between methylchloroisothiazolinone/methylisothiazolinone, methylisothiazolinone, and other isothiazolinones in workers at a plant producing binders for paints and glues , 2007, Contact dermatitis.

[37]  B. Gruvberger,et al.  Occupational contact allergy and dermatitis from methylisothiazolinone after contact with wallcovering glue and after a chemical burn from a biocide. , 2004, Dermatitis : contact, atopic, occupational, drug.

[38]  O. Gefeller,et al.  Guidelines for the descriptive presentation and statistical analysis of contact allergy data , 2004, Contact dermatitis.

[39]  J. Geier,et al.  No cross‐sensitization between MCI/MI, bunzisothiazolinone and Octylisothiazolinone , 1996, Contact dermatitis.

[40]  I. Dahlquist,et al.  Contact allergy to the active ingredients of Kathon® CG , 1987, Contact dermatitis.

[41]  S. Friedlander,et al.  Contact Dermatitis , 2008, Pediatric Practice Guidelines.

[42]  B. Gruvberger,et al.  Contact allergy to the active ingredients of Kathon CG in the guinea pig. , 1987, Acta dermato-venereologica.