Morphological and functional abnormalities in neuromuscular junctions of Drosophila melanogaster induced by human APP gene expression
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[1] M. Vitek,et al. Apolipoprotein E-Mimetics Inhibit Neurodegeneration and Restore Cognitive Functions in a Transgenic Drosophila Model of Alzheimer's Disease , 2009, PloS one.
[2] L. Guyant‐Maréchal. APP locus duplication causes Alzheimer disease with cerebral amyloid angiopathy , 2009, Journal of Neurological Sciences.
[3] S. Rohn,et al. FAD-mutation of APP is associated with a loss of its synaptotrophic activity , 2009, Neurobiology of Disease.
[4] P. Verstreken,et al. FM 1-43 labeling of synaptic vesicle pools at the Drosophila neuromuscular junction. , 2008, Methods in molecular biology.
[5] H. Anandatheerthavarada,et al. Amyloid Precursor Protein and Mitochondrial Dysfunction in Alzheimer's Disease , 2007, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.
[6] K. Beyreuther,et al. Axonal accumulation of synaptic markers in APP transgenic Drosophila depends on the NPTY motif and is paralleled by defects in synaptic plasticity , 2007, The European journal of neuroscience.
[7] J. Ting,et al. Amyloid precursor protein overexpression depresses excitatory transmission through both presynaptic and postsynaptic mechanisms , 2007, Proceedings of the National Academy of Sciences.
[8] Y. Larmet,et al. Unraveling in vivo Functions of Amyloid Precursor Protein: Insights from Knockout and Knockdown Studies , 2006, Neurodegenerative Diseases.
[9] V. Budnik,et al. The fly neuromuscular junction : structure and function , 2006 .
[10] Bassem A. Hassan,et al. Amyloid precursor protein promotes post‐developmental neurite arborization in the Drosophila brain , 2005, The EMBO journal.
[11] P. Hollenbeck. Mitochondria and Neurotransmission: Evacuating the Synapse , 2005, Neuron.
[12] E. Masliah,et al. Axonopathy and Transport Deficits Early in the Pathogenesis of Alzheimer's Disease , 2005, Science.
[13] Dominic M. Walsh,et al. Deciphering the Molecular Basis of Memory Failure in Alzheimer's Disease , 2004, Neuron.
[14] Nancy M Bonini,et al. Human neurodegenerative disease modeling using Drosophila. , 2003, Annual review of neuroscience.
[15] M. Mattson,et al. Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles Intracellular Aβ and Synaptic Dysfunction , 2003, Neuron.
[16] Kendal Broadie,et al. Living synaptic vesicle marker: Synaptotagmin‐GFP , 2002, Genesis.
[17] J. Hardy,et al. The Amyloid Hypothesis of Alzheimer ’ s Disease : Progress and Problems on the Road to Therapeutics , 2009 .
[18] B. de Strooper,et al. A cell biological perspective on Alzheimer's disease. , 2002, Annual review of cell and developmental biology.
[19] L. Goldstein,et al. Disruption of Axonal Transport and Neuronal Viability by Amyloid Precursor Protein Mutations in Drosophila , 2001, Neuron.
[20] D. Selkoe. Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid beta-protein. , 2001, Journal of Alzheimer's disease : JAD.
[21] S. Tomita,et al. Overexpression of human amyloid precursor protein in Drosophila. , 2000, Molecular cell biology research communications : MCBRC.
[22] Kang Hu,et al. High-Level Neuronal Expression of Aβ1–42 in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation , 2000, The Journal of Neuroscience.
[23] G. Matthews,et al. The Role of Mitochondria in Presynaptic Calcium Handling at a Ribbon Synapse , 2000, Neuron.
[24] V. Budnik,et al. The Drosophila β-Amyloid Precursor Protein Homolog Promotes Synapse Differentiation at the Neuromuscular Junction , 1999, The Journal of Neuroscience.
[25] K. White,et al. Neuronal overexpression of APPL, the Drosophila homologue of the amyloid precursor protein (APP), disrupts axonal transport , 1999, Current Biology.
[26] G. Collingridge,et al. Mechanisms contributing to the deficits in hippocampal synaptic plasticity in mice lacking amyloid precursor protein , 1999, Neuropharmacology.
[27] Veerle Baekelandt,et al. Early Phenotypic Changes in Transgenic Mice That Overexpress Different Mutants of Amyloid Precursor Protein in Brain* , 1999, The Journal of Biological Chemistry.
[28] Y. Kidokoro,et al. Two Distinct Pools of Synaptic Vesicles in Single Presynaptic Boutons in a Temperature-Sensitive Drosophila Mutant, shibire , 1998, Neuron.
[29] E. Masliah,et al. Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[30] E. Masliah,et al. Synaptic and neuritic alterations during the progression of Alzheimer's disease , 1994, Neuroscience Letters.
[31] D. Salmon,et al. Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment , 1991, Annals of neurology.