Prevalence, risk factors and causes of discordance in fibrosis staging by transient elastography and liver biopsy

Background and aims: Liver stiffness measurement (LSM) by transient elastography (TE) is widely used for the noninvasive assessment of fibrosis. Our objectives were to examine the prevalence, risk factors and causes of discordance between fibrosis estimated by TE and liver biopsy.

[1]  M. Ziol,et al.  Assessment of biliary fibrosis by transient elastography in patients with PBC and PSC , 2006, Hepatology.

[2]  E. DeLong,et al.  Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. , 1988, Biometrics.

[3]  D. Ouzan,et al.  Validation and comparison of indexes for fibrosis and cirrhosis prediction in chronic hepatitis C patients: proposal for a pragmatic approach classification without liver biopsies , 2006, Journal of viral hepatitis.

[4]  Ze-Zhou Song.  Acute viral hepatitis increases liver stiffness values measured by transient elastography , 2008, Hepatology.

[5]  D. Thabut,et al.  Prospective analysis of discordant results between biochemical markers and biopsy in patients with chronic hepatitis C. , 2004, Clinical chemistry.

[6]  R. Myers,et al.  Noninvasive diagnosis of nonalcoholic fatty liver disease. , 2009, Annals of hepatology.

[7]  R. Sacco,et al.  Transient elastography: a new surrogate marker of liver fibrosis influenced by major changes of transaminases , 2007, Journal of viral hepatitis.

[8]  L. Castéra,et al.  Variability of the area under the receiver operating characteristic curves in the diagnostic evaluation of liver fibrosis markers: impact of biopsy length and fragmentation , 2007, Alimentary pharmacology & therapeutics.

[9]  M. Ziol,et al.  Transient elastography: a new noninvasive method for assessment of hepatic fibrosis. , 2003, Ultrasound in medicine & biology.

[10]  R. Myers,et al.  Diagnostic accuracy of the aspartate aminotransferase‐to‐platelet ratio index for the prediction of hepatitis C–related fibrosis: A systematic review , 2007, Hepatology.

[11]  P. Giral,et al.  Sampling variability of liver biopsy in nonalcoholic fatty liver disease. , 2005, Gastroenterology.

[12]  J. Hanley,et al.  The meaning and use of the area under a receiver operating characteristic (ROC) curve. , 1982, Radiology.

[13]  Pierre Bedossa,et al.  Non‐invasive assessment of liver fibrosis by stiffness measurement in patients with chronic hepatitis B , 2009, Liver international : official journal of the International Association for the Study of the Liver.

[14]  Dario Conte,et al.  Reproducibility of transient elastography in the evaluation of liver fibrosis in patients with chronic liver disease , 2007, Gut.

[15]  Eva Herrmann,et al.  Performance of transient elastography for the staging of liver fibrosis: a meta-analysis. , 2008, Gastroenterology.

[16]  V. de Lédinghen,et al.  Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C. , 2005, Gastroenterology.

[17]  E. Schiff,et al.  Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection , 2002, American Journal of Gastroenterology.

[18]  A. fong,et al.  Utilization rates, complications and costs of percutaneous liver biopsy: a population‐based study including 4275 biopsies , 2008, Liver international : official journal of the International Association for the Study of the Liver.

[19]  S. Milani,et al.  Reliability of transient elastography for the diagnosis of advanced fibrosis in chronic hepatitis C , 2008, Gut.

[20]  V. Wong,et al.  Clinical factors associated with liver stiffness in hepatitis B e antigen-positive chronic hepatitis B patients. , 2009, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[21]  P. Crotty,et al.  Transient elastography for the noninvasive assessment of liver fibrosis: a multicentre Canadian study. , 2010, Canadian journal of gastroenterology = Journal canadien de gastroenterologie.

[22]  V. de Lédinghen,et al.  Feasibility of liver transient elastography with FibroScan® using a new probe for obese patients , 2010, Liver international : official journal of the International Association for the Study of the Liver.

[23]  J. Bruzzi,et al.  Liver biopsy. , 2001, The New England journal of medicine.

[24]  Gérard Forzy,et al.  Factors of accuracy of transient elastography (fibroscan) for the diagnosis of liver fibrosis in chronic hepatitis C , 2009, Hepatology.

[25]  R. Myers,et al.  FibroTest and FibroScan for the Prediction of Hepatitis C-Related Fibrosis: A Systematic Review of Diagnostic Test Accuracy , 2007, The American Journal of Gastroenterology.

[26]  Bryan Lau,et al.  Exceeding the limits of liver histology markers. , 2009, Journal of hepatology.

[27]  Christos Christidis,et al.  Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with chronic hepatitis C , 2005, Hepatology.

[28]  M. Campbell,et al.  Noninvasive Assessment of Liver Fibrosis by Measurement of Stiffness in Patients With Chronic Hepatitis C , 2006 .

[29]  P. Bedossa,et al.  Intraobserver and Interobserver Variations in Liver Biopsy Interpretation in Patients with Chronic Hepatitis C , 1994 .

[30]  M. Ziol,et al.  Features associated with success rate and performance of FibroScan measurements for the diagnosis of cirrhosis in HCV patients: a prospective study of 935 patients. , 2007, Journal of hepatology.

[31]  Intraobserver and interobserver variations in liver biopsy interpretation in patients with chronic hepatitis C. The French METAVIR Cooperative Study Group. , 1994, Hepatology.

[32]  F. Oberti,et al.  Reproducibility of liver stiffness measurement by ultrasonographic elastometry. , 2008, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[33]  A. Burroughs,et al.  Fibrosis staging in chronic hepatitis C: analysis of discordance between transient elastography and liver biopsy , 2009, Journal of viral hepatitis.

[34]  V. Paradis,et al.  Sampling variability of liver fibrosis in chronic hepatitis C , 2003, Hepatology.

[35]  Laurent Castera,et al.  Non-invasive evaluation of liver fibrosis using transient elastography. , 2008, Journal of hepatology.

[36]  O. Cummings,et al.  Design and validation of a histological scoring system for nonalcoholic fatty liver disease , 2005, Hepatology.

[37]  V. de Lédinghen,et al.  Pitfalls of liver stiffness measurement: A 5‐year prospective study of 13,369 examinations , 2010, Hepatology.

[38]  Julien Vergniol,et al.  Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease , 2010, Hepatology.

[39]  M. Manns,et al.  Biochemical surrogate markers of liver fibrosis and activity in a randomized trial of peginterferon alfa‐2b and ribavirin , 2003, Hepatology.