Neonatal Fc receptor expression in dendritic cells mediates protective immunity against colorectal cancer.

[1]  I. Mellman,et al.  Oncology meets immunology: the cancer-immunity cycle. , 2013, Immunity.

[2]  J. Banchereau,et al.  Dendritic-cell-based therapeutic cancer vaccines. , 2013, Immunity.

[3]  C. Datz,et al.  Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth , 2012, Nature.

[4]  Belgin Dogan,et al.  Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota , 2012, Science.

[5]  T. Levin,et al.  Incidence and mortality of colorectal adenocarcinoma in persons with inflammatory bowel disease from 1998 to 2010. , 2012, Gastroenterology.

[6]  T. Mcclanahan,et al.  IL-10 elicits IFNγ-dependent tumor immune surveillance. , 2011, Cancer cell.

[7]  L. Terracciano,et al.  Systematic analysis of proteins from different signaling pathways in the tumor center and the invasive front of colorectal cancer. , 2011, Human pathology.

[8]  N. Talley,et al.  Pulmonary-intestinal cross-talk in mucosal inflammatory disease , 2011, Mucosal Immunology.

[9]  C. Ulrich,et al.  Genetic Variation in Inflammatory Pathways Is Related to Colorectal Cancer Survival , 2011, Clinical Cancer Research.

[10]  J. Solassol,et al.  Autoantibody signatures: progress and perspectives for early cancer detection , 2011, Journal of cellular and molecular medicine.

[11]  Michael J. Bevan,et al.  CD8+ T Cells: Foot Soldiers of the Immune System , 2011, Immunity.

[12]  M. Haniffa,et al.  Human dendritic cell deficiency: the missing ID? , 2011, Nature Reviews Immunology.

[13]  E. Fiebiger,et al.  Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8−CD11b+ dendritic cells , 2011, Proceedings of the National Academy of Sciences.

[14]  T. Macdonald,et al.  Regulation of homeostasis and inflammation in the intestine. , 2011, Gastroenterology.

[15]  Charles Swanton,et al.  Genetic prognostic and predictive markers in colorectal cancer , 2011, Nature Reviews Cancer.

[16]  L. Zitvogel,et al.  The dendritic cell-tumor cross-talk in cancer. , 2011, Current opinion in immunology.

[17]  C. Jobin,et al.  The struggle within: Microbial influences on colorectal cancer , 2011, Inflammatory bowel diseases.

[18]  A. Fodor,et al.  Gut microbial diversity is reduced by the probiotic VSL#3 and correlates with decreased TNBS‐induced colitis , 2011, Inflammatory bowel diseases.

[19]  D. Metzger.  Interleukin-12 as an adjuvant for induction of protective antibody responses. , 2010, Cytokine.

[20]  D. Rader,et al.  Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function. , 2010, The Journal of clinical investigation.

[21]  M. Pallardy,et al.  Mechanisms of IL-12 Synthesis by Human Dendritic Cells Treated with the Chemical Sensitizer NiSO4 , 2010, The Journal of Immunology.

[22]  T. Kwan,et al.  Characterization of a major colon cancer susceptibility locus (Ccs3) on mouse chromosome 3 , 2010, Oncogene.

[23]  G. A. Lazar,et al.  Enhanced antibody half-life improves in vivo activity , 2010, Nature Biotechnology.

[24]  S. Qiao,et al.  An FcRn-dependent role for anti-flagellin immunoglobulin G in pathogenesis of colitis in mice. , 2009, Gastroenterology.

[25]  B. MacCraith,et al.  Human IgG antibody profiles differentiate between symptomatic patients with and without colorectal cancer , 2009, Gut.

[26]  Graham M Lord,et al.  Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells. , 2009, Cancer Cell.

[27]  R. Ober,et al.  Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice , 2009, Proceedings of the National Academy of Sciences.

[28]  L. Zitvogel,et al.  The immunogenicity of tumor cell death , 2009, Current opinion in oncology.

[29]  F. Osorio,et al.  Stimulation of dendritic cells via the dectin-1/Syk pathway allows priming of cytotoxic T-cell responses. , 2008, Blood.

[30]  R. Ober,et al.  Targeting the Neonatal Fc Receptor for Antigen Delivery Using Engineered Fc Fragments1 , 2008, The Journal of Immunology.

[31]  J. Andersen,et al.  Dependence of antibody-mediated presentation of antigen on FcRn , 2008, Proceedings of the National Academy of Sciences.

[32]  Carl G. Figdor,et al.  Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting , 2007, Nature Reviews Immunology.

[33]  V. Lazar,et al.  αEβ7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis , 2007, The Journal of experimental medicine.

[34]  Stefan Wirtz,et al.  Chemically induced mouse models of intestinal inflammation , 2007, Nature Protocols.

[35]  A. Kaser,et al.  Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria. , 2006, The Journal of clinical investigation.

[36]  Z. Trajanoski,et al.  Effector memory T cells, early metastasis, and survival in colorectal cancer. , 2005, The New England journal of medicine.

[37]  D. Nardelli-Haefliger,et al.  The importance of mucosal immunity in defense against epithelial cancers. , 2005, Current opinion in immunology.

[38]  D. Roopenian,et al.  Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells. , 2004, Immunity.

[39]  W. Lencer,et al.  Bidirectional transepithelial IgG transport by a strongly polarized basolateral membrane Fcgamma-receptor. , 2004, Molecular biology of the cell.

[40]  Makoto M Taketo,et al.  Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Δ716 Cdx2+/− compound mutant mice , 2003, Nature Genetics.

[41]  E. Choi,et al.  The MHC Class I-Like IgG Receptor Controls Perinatal IgG Transport, IgG Homeostasis, and Fate of IgG-Fc-Coupled Drugs1 , 2003, The Journal of Immunology.

[42]  G. Trinchieri,et al.  Interleukin-12 and the regulation of innate resistance and adaptive immunity , 2003, Nature Reviews Immunology.

[43]  Patricia W. Finn,et al.  Receptor-mediated Immunoglobulin G Transport Across Mucosal Barriers in Adult Life , 2002, The Journal of experimental medicine.

[44]  S. Hanash,et al.  Proteomics-based identification of protein gene product 9.5 as a tumor antigen that induces a humoral immune response in lung cancer. , 2001, Cancer research.

[45]  Emiko Mizoguchi,et al.  MHC Class I-Related Neonatal Fc Receptor for IgG Is Functionally Expressed in Monocytes, Intestinal Macrophages, and Dendritic Cells1 , 2001, The Journal of Immunology.

[46]  D. M. Penny,et al.  Identification of critical IgG binding epitopes on the neonatal Fc receptor. , 1997, Journal of molecular biology.

[47]  T. Flanigan,et al.  Comparison of the oral, rectal, and vaginal immunization routes for induction of antibodies in rectal and genital tract secretions of women , 1997, Infection and immunity.

[48]  G. Trinchieri,et al.  Interleukin-12 primes human CD4 and CD8 T cell clones for high production of both interferon-gamma and interleukin-10 , 1996, The Journal of experimental medicine.

[49]  I. Forgacs,et al.  Mucosal antibodies in inflammatory bowel disease are directed against intestinal bacteria. , 1996, Gut.

[50]  K. Rock,et al.  Targeting antigen into the phagocytic pathway in vivo induces protective tumour immunity , 1995, Nature Medicine.

[51]  G. Trinchieri,et al.  Interleukin‐12 is required for interferon‐γ production and lethality in lipopolysaccharide‐induced shock in mice , 1995, European journal of immunology.

[52]  A. Röder,et al.  Ulcerative colitis specific cytotoxic IgG-autoantibodies against colonic epithelial cancer cells. , 1988, Gut.

[53]  J. M. Macsween,et al.  Immunoglobulins associated with human tumours in vivo: IgG concentrations in eluates of colonic carcinomas. , 1980, British Journal of Cancer.

[54]  A. Jemal,et al.  Cancer statistics, 2012 , 2012, CA: a cancer journal for clinicians.

[55]  G. Trinchieri,et al.  Innate immune mechanisms of colitis and colitis-associated colorectal cancer , 2011, Nature Reviews Immunology.

[56]  青木 耕史.  Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc[+/Δ716] Cdx2[+/-] compound mutant mice , 2004 .