Noise-immune oximetry employing a new expression for oxygen saturation in blood

Oximetry is a technique to detect differential changes of oxygenation in hemoglobin. In previous work, we extended the classical mathematical model of oxygen saturation to reduce noise, to consider amplification parameters and detector's responsivity. We proposed a new expression for oxygen saturation in blood. This expression is less sensitive to noise, isolates the attenuation coefficients, is independent of multiplicative noise, and increases modulation. In the present work, we evaluate the feasibility of this new expression in thick tissue.