Microdroplet extraction assisted ultrasensitive Raman detection in complex oil.

The Raman detection of trace substances in complex oil is still a great challenge at present because of the strong disturbance of background activity and the suppression of intensity in spectra caused by complicated components. In this work, a simple and robust approach based on microdroplet liquid-liquid extraction for the real-time Raman spectroscopy monitoring of trace substances in complex oil is reported. Based on unbalanced chemical potentials between water and oil on a microfluidic chip, a target trace molecule is extracted from complex mineral oil to a water microdroplet. Benefiting from the real-time fluorescence intensities of fluorescein in a water microdroplet, the extraction performance is investigated and optimized. The optimal water microdroplet is implemented for the Raman detection of furfural in a complex mineral oil, a typical trace performance marker in electric power equipment, and this exhibits excellent sensitivity with a limit of detection (LOD) of 26 ppb. Compared to traditional detection technology for trace substances in complex oil (high performance liquid chromatography, HPLC), this method greatly simplified the process of measurement, reduced the volume of sample required, had a fast measurement time, and exhibited the prospect of real-time monitoring applications with high sensitivity, which not only promotes the development of oil quality but also enlarges existing knowledge related to using Raman spectroscopy in chem-/bio-sensing.

[1]  Shikuan Yang,et al.  Local hot charge density regulation: Vibration-free pyroelectric nanogenerator for effectively enhancing catalysis and in-situ surface enhanced Raman scattering monitoring , 2021 .

[2]  Xianming Kong,et al.  On-site separation and identification of polycyclic aromatic hydrocarbons from edible oil by TLC-SERS on diatomite photonic biosilica plate , 2021 .

[3]  Chundong Liu,et al.  Hierarchical Particle-In-Quasicavity Architecture for Ultratrace In Situ Raman Sensing and Its Application in Real-Time Monitoring of Toxic Pollutants. , 2020, Analytical chemistry.

[4]  Shunbo Li,et al.  Screening the Ion Compositions on Crystal Morphology Transitions by a Microfluidic Chip with a Well-Defined Concentration Gradient , 2020 .

[5]  Yingzhou Huang,et al.  Coherent Enhancement of Dual-Path Excited Remote SERS. , 2020, ACS applied materials & interfaces.

[6]  Lingxin Chen,et al.  SERS-based droplet microfluidics for high-throughput gradient analysis. , 2019, Lab on a chip.

[7]  D. Leung,et al.  Toward a mechanistic understanding of microfluidic droplet-based extraction and separation of lanthanides , 2019, Chemical Engineering Journal.

[8]  J. Karimi-Sabet,et al.  Liquid-liquid extraction of calcium using ionic liquids in spiral microfluidics , 2019, Chemical Engineering Journal.

[9]  Weigen Chen,et al.  Application of Self-Assembled Raman Spectrum-Enhanced Substrate in Detection of Dissolved Furfural in Insulating Oil , 2018, Nanomaterials.

[10]  Jinhui Peng,et al.  Intensified extraction and separation Pr (III)/Nd (III) from chloride solution in presence of a complexing agent using a serpentine microreactor , 2018, Chemical Engineering Journal.

[11]  Sheng Tang,et al.  Single-drop microextraction , 2018, TrAC Trends in Analytical Chemistry.

[12]  Gang Zhao,et al.  Simultaneous immunoassays of dual prostate cancer markers using a SERS-based microdroplet channel. , 2018, Biosensors & bioelectronics.

[13]  Weigen Chen,et al.  Silver nano-bulks surface-enhanced Raman spectroscopy used as rapid in-situ method for detection of furfural concentration in transformer oil , 2018, IEEE Transactions on Dielectrics and Electrical Insulation.

[14]  C. Zhang,et al.  SERS activated platform with three-dimensional hot spots and tunable nanometer gap , 2018 .

[15]  Wen Wang,et al.  Rapid identification of gutter oil by detecting the capsaicin using surface enhanced Raman spectroscopy , 2018 .

[16]  Weigen Chen,et al.  Charge Transfer Effect on Raman and Surface Enhanced Raman Spectroscopy of Furfural Molecules , 2017, Nanomaterials.

[17]  Ruijin Liao,et al.  Effects of temperature and aging on furfural partitioning in the oil-paper system of power transformers , 2016, IEEE Transactions on Dielectrics and Electrical Insulation.

[18]  Weigen Chen,et al.  Analysis of furfural dissolved in transformer oil based on confocal laser Raman spectroscopy , 2016, IEEE Transactions on Dielectrics and Electrical Insulation.

[19]  A. deMello,et al.  Wash-free magnetic immunoassay of the PSA cancer marker using SERS and droplet microfluidics. , 2016, Lab on a chip.

[20]  Yao-Wen Huang,et al.  Detection of polycyclic aromatic hydrocarbons from cooking oil using ultra-thin layer chromatography and surface enhanced Raman spectroscopy. , 2015, Journal of materials chemistry. B.

[21]  Y. Izawa,et al.  Furfural analysis in transformer oils using laser raman spectroscopy , 2015, IEEE Transactions on Dielectrics and Electrical Insulation.

[22]  D. Bakircioglu,et al.  Separation/Preconcentration System Based on Emulsion-Induced Breaking Procedure for Determination of Cadmium in Edible Oil Samples by Flow Injection-Flame Atomic Absorption Spectrometry , 2015, Food Analytical Methods.

[23]  Yingzhou Huang,et al.  Nanowire-supported plasmonic waveguide for remote excitation of surface-enhanced Raman scattering , 2014, Light: Science & Applications.

[24]  Daniel Martin,et al.  The effect of acid accumulation in power-transformer oil on the aging rate of paper insulation , 2014, IEEE Electrical Insulation Magazine.

[25]  F. Ahmadi,et al.  ANALYZED AND PROPOSED MECHANISM OF PHOTOCATALYTIC DEGRADATION OF FURFURAL AT TIO2 NANO-PARTICLES BY HPLC-UV AND LC-MASS METHODS , 2014 .

[26]  Nicola Caporaso,et al.  Capsaicinoids, antioxidant activity, and volatile compounds in olive oil flavored with dried chili pepper (Capsicum annuum) , 2013 .

[27]  Weihua Li,et al.  High-throughput particle manipulation by hydrodynamic, electrokinetic, and dielectrophoretic effects in an integrated microfluidic chip. , 2013, Biomicrofluidics.

[28]  Hsiang-Yu Wang,et al.  Enhanced fluorescence detection using liquid-liquid extraction in a microfluidic droplet system. , 2012, Lab on a chip.

[29]  S. Chellam,et al.  Multi-elemental characterization of tunnel and road dusts in Houston, Texas using dynamic reaction cell-quadrupole-inductively coupled plasma-mass spectrometry: evidence for the release of platinum group and anthropogenic metals from motor vehicles. , 2012, Analytica chimica acta.

[30]  A. Abu-Siada,et al.  A Novel Fuzzy-Logic Approach for Furan Estimation in Transformer Oil , 2012, IEEE Transactions on Power Delivery.

[31]  Ahmed Abu-Siada,et al.  Correlation of furan concentration and spectral response of transformer oil-using expert systems , 2011 .

[32]  H. Woo,et al.  Solubility of red pepper (Capsicum annum) oil in near- and supercritical carbon dioxide and quantification of capsaicin , 2011 .

[33]  Ahmad Gholami,et al.  Investigation of the ambient temperature effects on transformer’s insulation life , 2011 .

[34]  Issouf Fofana,et al.  Characterization of aging transformer oil–pressboard insulation using some modern diagnostic techniques , 2011 .

[35]  M. Murkovic,et al.  Analysis of 5-hydroxymethyl-2-furoic acid (HMFA) the main metabolite of alimentary 5-hydroxymethyl-2-furfural (HMF) with HPLC and GC in urine , 2010 .

[36]  A. G. Frenich,et al.  Polycyclic aromatic hydrocarbons in food and beverages. Analytical methods and trends. , 2010, Journal of chromatography. A.

[37]  V. Studer,et al.  Microfluidic droplet-based liquid-liquid extraction. , 2008, Analytical chemistry.

[38]  I. Hohlein,et al.  Aging of cellulose at transformer service temperatures. Part 2. Influence of moisture and temperature on degree of polymerization and formation of furanic compounds in free-breathing systems , 2005, IEEE Electrical Insulation Magazine.

[39]  R. M. Morais,et al.  Furfural analysis for assessing degradation of thermally upgraded papers in transformer insulation , 1999 .

[40]  Giovanni Camino,et al.  Origin of furanic compounds in thermal degradation of cellulosic insulating paper , 1998 .