African histoplasmosis: therapeutic efficacy of itraconazole

A patient with African form of histoplasmosis was treated for 7 years with ketoconazole, with no response; after a 9‐month daily treatment with 100 mg of itraconazole the patient was successfully cured. No evidence of relapse was observed during the 3‐year follow‐up period.

[1]  G. Medoff.  The 10 Most Common Questions About Fungal Infection , 1993 .

[2]  K. K. Lai,et al.  Measles vaccination in a small cohort of hiv-infected adults , 1993 .

[3]  W. Symonds,et al.  Focus on itraconazole: A broad-spectrum antifungal agent for treatment of blastomycosis and histoplasmosis , 1993 .

[4]  M. Saag,et al.  Itraconazole therapy for blastomycosis and histoplasmosis , 1992 .

[5]  H. Faust,et al.  Cutaneous Histoplasma capsulatum in a nonimmunocompromised patient with previously treated cutaneous Mycobacterium kansasii. , 1991, Journal of the American Academy of Dermatology.

[6]  R. M. Tucker,et al.  Adverse events associated with itraconazole in 189 patients on chronic therapy. , 1990, The Journal of antimicrobial chemotherapy.

[7]  J. Graybill,et al.  Fungal infections and their management. , 1990, British journal of clinical practice. Supplement.

[8]  B. Gazzard,et al.  Histoplasmosis in a UK patient treated with itraconazole. , 1990, AIDS (London).

[9]  I. Weisman,et al.  Tolerance to and efficacy of itraconazole in treatment of systemic mycoses: preliminary results. , 1987, Reviews of infectious diseases.

[10]  R. Negroni,et al.  Oral treatment of paracoccidioidomycosis and histoplasmosis with itraconazole in humans. , 1987, Reviews of infectious diseases.

[11]  B. Osuntokun,et al.  Orbital histoplasmosis due to Histoplasma capsulatum var. duboisii: successful treatment with Septrin. , 1986, The Journal of tropical medicine and hygiene.

[12]  G. Cauwenbergh,et al.  Itraconazole (R 51 211): A clinical review of its antimycotic activity in dermatology, gynecology, and internal medicine , 1986 .

[13]  J. Lesbordes,et al.  Observation d'une histoplasmose à «histoplasma duboisii» traitée par le kétoconazole à Bangui (R.C.A.) , 1986 .

[14]  González Jc,et al.  Tratamiento exitoso de un caso de histoplasmosis africana con miconazol (daktarin) , 1986 .

[15]  W. Tucker,et al.  Reversible adrenal insufficiency induced by ketoconazole. , 1985, JAMA.

[16]  G. Guillet,et al.  [Does ketoconazole have a delayed anti-androgen effect?]. , 1985, Annales de dermatologie et de vénéréologie.

[17]  J. Galgiani,et al.  High-dose ketoconazole therapy and adrenal and testicular function in humans. , 1984, Archives of internal medicine.

[18]  K. Ishak,et al.  Hepatic injury associated with ketoconazole therapy. Analysis of 33 cases. , 1984, Gastroenterology.

[19]  R. Hay,et al.  Treatment of African histoplasmosis with ketoconazole. , 1983, Transactions of the Royal Society of Tropical Medicine and Hygiene.