Cortical Evoked Potentials

Buttressed by some undeniably sloppy evoked potential research there are some who would dismiss out of hand the recording of electrical signals from the human scalp as being comparable to “holding an oscilloscope probe six feet in diameter up to a computer and pronouncing from the resultant waveform on the underlying structure and function”. Such extreme views are often associated with an implication that the method of recording electrical activities of individual nerve cells is the only electrophysiological technique which merits serious scientific consideration. This view has more than a grain of truth in it. Although a fair case can be made for the clinical possibilities of scalp recording, it is certainly true that the contribution made by the scalp recording method to our present day understanding of brain function are very much less than the contributions made by single-cell recording. It could be argued that although a deal of taxpayers’ money has been absorbed by evoked potential research, the scientific returns have been many articles, much equivocal data, but little additional understanding of brain function.

[1]  H G Vaughan,et al.  Metacontrast and Evoked Potentials: A Reappraisal , 1968, Science.

[2]  L. H. Van Der Tweel,et al.  HUMAN VISUAL RESPONSES TO SINUSOIDALLY MODULATED LIGHT. , 1965, Electroencephalography and clinical neurophysiology.

[3]  W. Cobb,et al.  Cerebral Potentials evoked by Pattern Reversal and their Suppression in Visual Rivalry , 1967, Nature.

[4]  David Regan,et al.  Objective Method of Measuring the Relative Spectral-Luminosity Curve in Man , 1970 .

[5]  H. Spekreijse,et al.  Electrophysiological Correlate of Binocular Depth Perception in Man , 1970, Nature.

[6]  H G Vaughan,et al.  Averaged Evoked Responses in Vigilance and Discrimination: A Reassessment , 1969, Science.

[7]  A M Halliday,et al.  Differences between the occipital distribution of upper and lower field pattern-evoked responses in man. , 1971, Brain research.

[8]  M. Cohen.  The contribution by glial cells to surface recordings from the optic nerve of an amphibian , 1970, The Journal of physiology.

[9]  D Regan,et al.  A high frequency mechanism which underlies visual evoked potentials. , 1968, Electroencephalography and clinical neurophysiology.

[10]  G. Westheimer.  Spatial interaction in human cone vision , 1967, The Journal of physiology.

[11]  F. Campbell,et al.  Electrophysiological evidence for the existence of orientation and size detectors in the human visual system , 1970, The Journal of physiology.

[12]  A M Halliday,et al.  Changes in pattern‐evoked responses in man associated with the vertical and horizontal meridians of the visual field , 1970, The Journal of physiology.

[13]  D. Mackay.  Evoked Potentials reflecting Interocular and Monocular Suppression , 1968, Nature.

[14]  D Regan,et al.  A method of evoking contour-specific scalp potentials by chromatic checkerboard patterns. , 1971, Vision Research.

[15]  H. Spekreijse,et al.  SIGNAL TRANSPORT AND RECTIFICATION IN THE HUMAN EVOKED‐RESPONSE SYSTEM * , 1969, Annals of the New York Academy of Sciences.

[16]  D. Lindsley,et al.  Attention, Vigilance, and Cortical Evoked-Potentials in Humans , 1964, Science.

[17]  D. Regan,et al.  A method of measuring the potentials evoked by simultaneous stimulation of different retinal regions. , 1970, Electroencephalography and clinical neurophysiology.

[18]  D Regan,et al.  Clinical investigation of lesions of the visual pathway: a new objective technique. , 1969, Journal of neurology, neurosurgery, and psychiatry.

[19]  L. H. Tweel,et al.  Linearization of Evoked Responses to Sine Wave-modulated Light by Noise , 1965, Nature.

[20]  H. Spekreijse,et al.  Interocular sustained suppression: correlations with evoked potential amplitude and distribution. , 1972, Vision research.

[21]  D Regan,et al.  Evoked potential and psychophysical correlates of changes in stimulus colour and intensity. , 1970, Vision research.

[22]  R. L. Valois,et al.  Analysis of response patterns of LGN cells. , 1966, Journal of the Optical Society of America.

[23]  D. Jeffreys,et al.  Cortical Source Locations of Pattern-related Visual Evoked Potentials recorded from the Human Scalp , 1971, Nature.

[24]  David Regan,et al.  Evoked potentials and sensation , 1968 .

[25]  H Spekreijse,et al.  Rectification in the goldfish retina: analysis by sinusoidal and auxiliary stimulation. , 1969, Vision research.

[26]  D Regan,et al.  Independence of evoked potentials and apparent size. , 1971, Vision research.

[27]  S. L. Chorover,et al.  Metacontrast: Its Relation to Evoked Potentials , 1966, Science.

[28]  D. Regan.  Evoked Potentials in Psychology, Sensory Physiology and Clinical Medicine , 1972 .

[29]  L. Tweel.  SOME PROBLEMS IN VISION REGARDED WITH RESPECT TO LINEARITY AND FREQUENCY RESPONSE * , 1961 .

[30]  D. Regan.  Some characteristics of average steady-state and transient responses evoked by modulated light. , 1966, Electroencephalography and clinical neurophysiology.