Bacillus anthracis’ lethal toxin induces broad transcriptional responses in human peripheral monocytes

[1]  J. Metcalf,et al.  Resistance of Human Alveolar Macrophages to Bacillus anthracis Lethal Toxin1 , 2009, The Journal of Immunology.

[2]  J. Metcalf,et al.  Gene expression profiling of human alveolar macrophages infected by B. anthracis spores demonstrates TNF-α and NF-κb are key components of the innate immune response to the pathogen , 2009, BMC infectious diseases.

[3]  D. Soppet,et al.  Transcriptional and apoptotic responses of THP-1 cells to challenge with toxigenic, and non-toxigenic Bacillus anthracis , 2008, BMC Immunology.

[4]  T. Hohl,et al.  Monocyte-mediated defense against microbial pathogens. , 2008, Annual review of immunology.

[5]  E. Leffel,et al.  Pathology of Inhalational Anthrax Infection in the African Green Monkey , 2007, Veterinary pathology.

[6]  Wei Li,et al.  Anthrax lethal toxin paralyzes actin‐based motility by blocking Hsp27 phosphorylation , 2007, The EMBO journal.

[7]  F. Taylor,et al.  Sepsis and pathophysiology of anthrax in a nonhuman primate model. , 2006, The American journal of pathology.

[8]  T. Peretz,et al.  Role of endothelial heparanase in delayed-type hypersensitivity. , 2006, Blood.

[9]  J. Peterson,et al.  GeneChip Analyses of Global Transcriptional Responses of Murine Macrophages to the Lethal Toxin of Bacillus anthracis , 2005, Infection and Immunity.

[10]  E. Elkord,et al.  Human monocyte isolation methods influence cytokine production from in vitro generated dendritic cells , 2005, Immunology.

[11]  S. Der,et al.  Differentiation of human monocytic cell lines confers susceptibility to Bacillus anthracis lethal toxin , 2004, Cellular microbiology.

[12]  C. Moratz,et al.  Toll-Like Receptor Signaling Alters the Expression of Regulator of G Protein Signaling Proteins in Dendritic Cells: Implications for G Protein-Coupled Receptor Signaling , 2004, The Journal of Immunology.

[13]  T. Fukao.  Immune system paralysis by anthrax lethal toxin: the roles of innate and adaptive immunity. , 2004, The Lancet. Infectious diseases.

[14]  T. Popović,et al.  Pathology and pathogenesis of bioterrorism-related inhalational anthrax. , 2003, The American journal of pathology.

[15]  Damien Chaussabel,et al.  Unique gene expression profiles of human macrophages and dendritic cells to phylogenetically distinct parasites. , 2003, Blood.

[16]  D. Mosser,et al.  The many faces of macrophage activation , 2003, Journal of leukocyte biology.

[17]  Tanja Popovic,et al.  Investigation of Bioterrorism-Related Anthrax, United States, 2001: Epidemiologic Findings , 2002, Emerging infectious diseases.

[18]  Rafael Villasmil,et al.  Effect of Bacillus anthracis lethal toxin on human peripheral blood mononuclear cells , 2002, FEBS letters.

[19]  N. Rice,et al.  Rapid lipopolysaccharide‐induced differentiation of CD14+ monocytes into CD83+ dendritic cells is modulated under serum‐free conditions by exogenously added IFN‐γ and endogenously produced IL‐10 , 2001, European journal of immunology.

[20]  R. Bhatnagar,et al.  Anthrax Toxin , 2001, Critical reviews in microbiology.

[21]  M. Mock,et al.  Lethal factor of Bacillus anthracis cleaves the N-terminus of MAPKKs: analysis of the intracellular consequences in macrophages. , 2000, International journal of medical microbiology : IJMM.

[22]  O. Lider,et al.  Extracellular matrix moieties, cytokines, and enzymes: dynamic effects on immune cell behavior and inflammation , 2000, Journal of leukocyte biology.

[23]  J. Harrison,et al.  Expression of CCR5 Increases during Monocyte Differentiation and Directly Mediates Macrophage Susceptibility to Infection by Human Immunodeficiency Virus Type 1 , 1998, Journal of Virology.

[24]  K D Paull,et al.  Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor. , 1998, Science.

[25]  J. Kienast,et al.  Increase of Plasminogen Activator Inhibitor Levels Predicts Outcome of Leukocytopenic Patients with Sepsis , 1996, Thrombosis and Haemostasis.

[26]  B. Bloom,et al.  Role of Macrophage Oxidative Burst in the Action of Anthrax Lethal Toxin , 1994, Molecular medicine.

[27]  D. Acosta,et al.  On the role of macrophages in anthrax. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[28]  A. Mantovani,et al.  Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4. , 1993, Science.

[29]  C. Quinn,et al.  Purification of anthrax-toxin components by high-performance anion-exchange, gel-filtration and hydrophobic-interaction chromatography. , 1988, The Biochemical journal.

[30]  S. Leppla,et al.  Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[31]  D. Chaussabel,et al.  cells to phylogenetically distinct parasites Unique gene expression profiles of human macrophages and dendritic , 2013 .

[32]  I. Cohen,et al.  Expression of heparanase by platelets and circulating cells of the immune system: possible involvement in diapedesis and extravasation. , 1992, Invasion & metastasis.

[33]  R. van Furth.  Origin and turnover of monocytes and macrophages. , 1989, Current topics in pathology. Ergebnisse der Pathologie.