Intracellular accumulation of tau oligomers in astrocytes and their synaptotoxic action rely on Amyloid Precursor Protein Intracellular Domain-dependent expression of Glypican-4
暂无分享,去创建一个
O. Arancio | L. D’Adamio | R. Piacentini | C. Ripoli | Giuseppe Aceto | D. D. Li Puma | Claudio Grassi | G. Lazzarino | D. L. Puma | Giulia Puliatti | Renata Mangione | E. Acquarone
[1] A. Goate,et al. Astrocyte-secreted glypican-4 drives APOE4-dependent tau hyperphosphorylation , 2022, Proceedings of the National Academy of Sciences of the United States of America.
[2] J. Middeldorp,et al. The Role of Astrocytes in Synapse Loss in Alzheimer's Disease: A Systematic Review , 2022, Frontiers in Cellular Neuroscience.
[3] M. Diamond,et al. The dual fates of exogenous tau seeds: Lysosomal clearance versus cytoplasmic amplification , 2022, The Journal of biological chemistry.
[4] O. Arancio,et al. Extracellular tau oligomers affect extracellular glutamate handling by astrocytes through downregulation of GLT‐1 expression and impairment of NKA1A2 function , 2022, Neuropathology and applied neurobiology.
[5] Tetsuya Takahashi,et al. Amyloid Beta Is Internalized via Macropinocytosis, an HSPG- and Lipid Raft-Dependent and Rac1-Mediated Process , 2022, Frontiers in Molecular Neuroscience.
[6] A. Robinson,et al. Heparan Sulfate Proteoglycans (HSPGs) Serve as the Mediator Between Monomeric Tau and Its Subsequent Intracellular ERK1/2 Pathway Activation , 2022, Journal of Molecular Neuroscience.
[7] Onur Dagliyan,et al. Engineering a switchable single‐chain TEV protease to control protein maturation in living neurons , 2022, Bioengineering & translational medicine.
[8] G. Taglialatela,et al. Aβ/tau oligomer interplay at human synapses supports shifting therapeutic targets for Alzheimer’s disease , 2021, Cellular and Molecular Life Sciences.
[9] Dan Liu,et al. The role of pathological tau in synaptic dysfunction in Alzheimer’s diseases , 2021, Translational Neurodegeneration.
[10] Ryan S. O'Dell,et al. Association of entorhinal cortical tau deposition and hippocampal synaptic density in older individuals with normal cognition and early Alzheimer's disease , 2021, Neurobiology of Aging.
[11] J. Cummings,et al. The Unifying Hypothesis of Alzheimer’s Disease: Heparan Sulfate Proteoglycans/Glycosaminoglycans Are Key as First Hypothesized Over 30 Years Ago , 2021, Frontiers in Aging Neuroscience.
[12] Xinlin Chen,et al. Glypican 4 Regulates Aβ Internalization in Neural Stem Cells Partly via Low-Density Lipoprotein Receptor-Related Protein 1 , 2021, Frontiers in Cellular Neuroscience.
[13] A. Cattaneo,et al. Non-Canonical Roles of Tau and Their Contribution to Synaptic Dysfunction , 2021, International journal of molecular sciences.
[14] R. Linhardt,et al. The Sulfation Code of Tauopathies: Heparan Sulfate Proteoglycans in the Prion Like Spread of Tau Pathology , 2021, Frontiers in Molecular Biosciences.
[15] L. Grinberg,et al. Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy , 2021, Nature Communications.
[16] Xiao-qing Tang,et al. Tau internalization: A complex step in tau propagation , 2021, Ageing Research Reviews.
[17] P. Verstreken,et al. Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation , 2021, Neuron.
[18] N. Toni,et al. Tau accumulation in astrocytes of the dentate gyrus induces neuronal dysfunction and memory deficits in Alzheimer’s disease , 2020, Nature Neuroscience.
[19] T. Arzberger,et al. Contribution of the astrocytic tau pathology to synapse loss in progressive supranuclear palsy and corticobasal degeneration , 2020, Brain pathology.
[20] A. Palamara,et al. Ca2+‐dependent release of ATP from astrocytes affects herpes simplex virus type 1 infection of neurons , 2020, Glia.
[21] V. Gradinaru,et al. LRP1 is a master regulator of tau uptake and spread , 2020, Nature.
[22] Heparan Sulfate , 2020, Definitions.
[23] A. Palamara,et al. Herpes Simplex Virus Type‐1 Infection Impairs Adult Hippocampal Neurogenesis via Amyloid‐β Protein Accumulation , 2019, Stem cells.
[24] T. Hromádka,et al. Intersection of pathological tau and microglia at the synapse , 2019, Acta neuropathologica communications.
[25] Stephen Salloway,et al. A multicentre longitudinal study of flortaucipir (18F) in normal ageing, mild cognitive impairment and Alzheimer’s disease dementia , 2019, Brain : a journal of neurology.
[26] C. Colussi,et al. Altered Nup153 Expression Impairs the Function of Cultured Hippocampal Neural Stem Cells Isolated from a Mouse Model of Alzheimer’s Disease , 2019, Molecular Neurobiology.
[27] Brian A. Gordon,et al. Influence of tau PET, amyloid PET, and hippocampal volume on cognition in Alzheimer disease , 2018, Neurology.
[28] J. Ávila,et al. The Role of Microglia in the Spread of Tau: Relevance for Tauopathies , 2018, Front. Cell. Neurosci..
[29] Y. Xiong,et al. Ca2+-Dependent and Ca2+-Independent ATP Release in Astrocytes , 2018, Front. Mol. Neurosci..
[30] L. Hsieh‐Wilson,et al. Specific glycosaminoglycan chain length and sulfation patterns are required for cell uptake of tau versus α-synuclein and β-amyloid aggregates , 2018, The Journal of Biological Chemistry.
[31] Joris de Wit,et al. Heparan Sulfate Proteoglycans as Emerging Players in Synaptic Specificity , 2018, Front. Mol. Neurosci..
[32] E. Mandelkow,et al. Extracellular low-n oligomers of tau cause selective synaptotoxicity without affecting cell viability , 2017, Alzheimer's & Dementia.
[33] N. J. Allen,et al. Astrocyte-Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation , 2017, Neuron.
[34] T. Müller,et al. Small things matter: Implications of APP intracellular domain AICD nuclear signaling in the progression and pathogenesis of Alzheimer’s disease , 2017, Progress in Neurobiology.
[35] K. Kosik,et al. Tau Internalization is Regulated by 6-O Sulfation on Heparan Sulfate Proteoglycans (HSPGs) , 2017, Scientific Reports.
[36] A. Palmeri,et al. LTP and memory impairment caused by extracellular Aβ and Tau oligomers is APP-dependent , 2017, eLife.
[37] O. Arancio,et al. Reduced gliotransmitter release from astrocytes mediates tau‐induced synaptic dysfunction in cultured hippocampal neurons , 2017, Glia.
[38] Rosemary J. Jackson,et al. Tau association with synaptic vesicles causes presynaptic dysfunction , 2017, Nature Communications.
[39] S. Grant,et al. ATP from synaptic terminals and astrocytes regulates NMDA receptors and synaptic plasticity through PSD-95 multi-protein complex , 2016, Scientific Reports.
[40] S. J. Guzman,et al. P2Y Receptors in Synaptic Transmission and Plasticity: Therapeutic Potential in Cognitive Dysfunction , 2016, Neural plasticity.
[41] A. Palmeri,et al. Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory , 2016, Scientific Reports.
[42] V. Lee,et al. Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases , 2014, Nature Medicine.
[43] J. Yates,et al. Unbiased Discovery of Glypican as a Receptor for LRRTM4 in Regulating Excitatory Synapse Development , 2013, Neuron.
[44] F. Brodsky,et al. Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds , 2013, Proceedings of the National Academy of Sciences.
[45] Ottavio Arancio,et al. An Intracellular Threonine of Amyloid-β Precursor Protein Mediates Synaptic Plasticity Deficits and Memory Loss , 2013, PloS one.
[46] Stephen J. Smith,et al. Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors , 2012, Nature.
[47] J. Esko,et al. Heparan sulfate proteoglycans. , 2011, Cold Spring Harbor perspectives in biology.
[48] U. Sengupta,et al. Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice , 2011, Molecular Neurodegeneration.
[49] G. Perea,et al. GLIA modulates synaptic transmission , 2010, Brain Research Reviews.
[50] Katrin Marcus,et al. The amyloid precursor protein intracellular domain (AICD) as modulator of gene expression, apoptosis, and cytoskeletal dynamics—Relevance for Alzheimer's disease , 2008, Progress in Neurobiology.
[51] Y. Suh,et al. Phosphorylation of Amyloid Precursor Protein (APP) at Thr668 Regulates the Nuclear Translocation of the APP Intracellular Domain and Induces Neurodegeneration , 2006, Molecular and Cellular Biology.
[52] F. Bellia,et al. Simultaneous high performance liquid chromatographic separation of purines, pyrimidines, N-acetylated amino acids, and dicarboxylic acids for the chemical diagnosis of inborn errors of metabolism. , 2005, Clinical biochemistry.
[53] R. Nitsch,et al. The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor , 2004, Journal of Cell Science.
[54] S. Koizumi,et al. Dynamic inhibition of excitatory synaptic transmission by astrocyte-derived ATP in hippocampal cultures , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[55] M. Tabaton,et al. Generation of an Apoptotic Intracellular Peptide by γ-Secretase Cleavage of Alzheimer's Amyloid ß Protein Precursor , 2000 .