Curcumin as a Modulator of P-Glycoprotein in Cancer: Challenges and Perspectives
暂无分享,去创建一个
[1] T. Efferth,et al. Modulation of P-glycoprotein activity by novel synthetic curcumin derivatives in sensitive and multidrug-resistant T-cell acute lymphoblastic leukemia cell lines. , 2016, Toxicology and applied pharmacology.
[2] Junyan Wu,et al. Amphiphilic Copolymeric Micelles for Doxorubicin and Curcumin Co-Delivery to Reverse Multidrug Resistance in Breast Cancer. , 2016, Journal of biomedical nanotechnology.
[3] Pornsiri Pitchakarn,et al. Chemosensitizing effects of synthetic curcumin analogs on human multi-drug resistance leukemic cells. , 2016, Chemico-biological interactions.
[4] E. Sousa,et al. Curcumin: A Natural Lead for Potential New Drug Candidates. , 2015, Current medicinal chemistry.
[5] A. Rathore,et al. Enhanced oral bioavailability and anticancer activity of novel curcumin loaded mixed micelles in human lung cancer cells. , 2015, Phytomedicine : international journal of phytotherapy and phytopharmacology.
[6] P. Tu,et al. Synergistically Improved Anti-tumor Efficacy by Co-delivery Doxorubicin and Curcumin Polymeric Micelles. , 2015, Macromolecular bioscience.
[7] Xiangliang Yang,et al. Doxorubicin and curcumin co-delivery by lipid nanoparticles for enhanced treatment of diethylnitrosamine-induced hepatocellular carcinoma in mice. , 2015, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[8] Yan Li,et al. Heterocyclic cyclohexanone monocarbonyl analogs of curcumin can inhibit the activity of ATP-binding cassette transporters in cancer multidrug resistance. , 2015, Biochemical pharmacology.
[9] Pornsiri Pitchakarn,et al. Curcumin-loaded PLGA nanoparticles conjugated with anti- P-glycoprotein antibody to overcome multidrug resistance. , 2014, Asian Pacific journal of cancer prevention : APJCP.
[10] E. Sousa,et al. The network of P‐glycoprotein and microRNAs interactions , 2014, International journal of cancer.
[11] S. Safe,et al. The drug resistance suppression induced by curcuminoids in colon cancer SW-480 cells is mediated by reactive oxygen species-induced disruption of the microRNA-27a-ZBTB10-Sp axis. , 2013, Molecular nutrition & food research.
[12] J. Kanwar,et al. Curcumin Regulates Colon Cancer by Inhibiting P-Glycoprotein in In-situ Cancerous Colon Perfusion Rat Model , 2013, Journal of cancer science & therapy.
[13] Vipin Saxena,et al. Polymeric mixed micelles for delivery of curcumin to multidrug resistant ovarian cancer. , 2013, Journal of biomedical nanotechnology.
[14] Lei Li,et al. Effect of curcumin on human colon cancer multidrug resistance in vitro and in vivo , 2013, Clinics.
[15] M. X. Fernandes,et al. Structure and ligand-based design of P-glycoprotein inhibitors: a historical perspective. , 2012, Current pharmaceutical design.
[16] Pornsiri Pitchakarn,et al. Enhancement of cellular uptake and cytotoxicity of curcumin-loaded PLGA nanoparticles by conjugation with anti-P-glycoprotein in drug resistance cancer cells , 2012, Acta Pharmacologica Sinica.
[17] Yifeng Pan,et al. Reversion of multidrug resistance by co-encapsulation of doxorubicin and curcumin in chitosan/poly(butyl cyanoacrylate) nanoparticles. , 2012, International journal of pharmaceutics.
[18] Liang Wang,et al. Curcumin potentiates antitumor activity of l-asparaginase via inhibition of the AKT signaling pathway in acute lymphoblastic leukemia , 2012, Leukemia & lymphoma.
[19] Hong-gang Yu,et al. Curcumin reverses chemoresistance of human gastric cancer cells by downregulating the NF-κB transcription factor. , 2011, Oncology reports.
[20] Zhishu Huang,et al. Design, synthesis, and biological evaluation of curcumin analogues as multifunctional agents for the treatment of Alzheimer's disease. , 2011, Bioorganic & medicinal chemistry.
[21] Dong Xu,et al. Curcumin prevents induced drug resistance: A novel function? , 2011, Chinese journal of cancer research = Chung-kuo yen cheng yen chiu.
[22] Chuanbing Shi,et al. Upregulation of p53 Expression in Patients with Colorectal Cancer by Administration of Curcumin , 2011, Cancer investigation.
[23] P. Rojsitthisak,et al. Synthesis, Characterization and Biological Evaluation of Succinate Prodrugs of Curcuminoids for Colon Cancer Treatment , 2011, Molecules.
[24] S. Horie,et al. Combined inhibitory effects of soy isoflavones and curcumin on the production of prostate‐specific antigen , 2010, The Prostate.
[25] B. Aggarwal,et al. Demethoxycurcumin suppresses migration and invasion of MDA-MB-231 human breast cancer cell line. , 2010, European journal of pharmacology.
[26] F. Sharom,et al. ABC efflux pump-based resistance to chemotherapy drugs. , 2009, Chemical reviews.
[27] S. Ganta,et al. Coadministration of Paclitaxel and curcumin in nanoemulsion formulations to overcome multidrug resistance in tumor cells. , 2009, Molecular pharmaceutics.
[28] Jian Xiao,et al. Exploration and synthesis of curcumin analogues with improved structural stability both in vitro and in vivo as cytotoxic agents. , 2009, Bioorganic & medicinal chemistry.
[29] B. Aggarwal,et al. Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature. , 2008, Biochemical pharmacology.
[30] Razelle Kurzrock,et al. Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer , 2008, Clinical Cancer Research.
[31] S. Vareed,et al. Pharmacokinetics of Curcumin Conjugate Metabolites in Healthy Human Subjects , 2008, Cancer Epidemiology Biomarkers & Prevention.
[32] Su-Nam Kim,et al. Synthesis of curcumin mimics with multidrug resistance reversal activities. , 2008, Bioorganic & medicinal chemistry.
[33] D. Panda,et al. Curcumin inhibits FtsZ assembly: an attractive mechanism for its antibacterial activity. , 2008, The Biochemical journal.
[34] Chang Gun Kim,et al. Curcumin down-regulates the multidrug-resistance mdr1b gene by inhibiting the PI3K/Akt/NF kappa B pathway. , 2008, Cancer letters.
[35] Robert A Newman,et al. Bioavailability of curcumin: problems and promises. , 2007, Molecular pharmaceutics.
[36] D. Newman,et al. Natural products as sources of new drugs over the last 25 years. , 2007, Journal of natural products.
[37] S. Ambudkar,et al. Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin , 2007, Molecular and Cellular Biochemistry.
[38] L. Platanias,et al. Curcumin induces apoptosis via inhibition of PI3′-kinase/AKT pathway in Acute T cell Leukemias , 2006, Apoptosis.
[39] G. N. Sastry,et al. Recent advances in molecular modeling and medicinal chemistry aspects of phospho-glycoprotein. , 2006, Current drug metabolism.
[40] B. Aggarwal,et al. Curcumin: Getting Back to the Roots , 2005, Annals of the New York Academy of Sciences.
[41] Ricky A. Sharma,et al. Curcumin: the story so far. , 2005, European journal of cancer.
[42] Jianguo Cao,et al. Effect of curcumin on multidrug resistance in resistant human gastric carcinoma cell line SGC7901/VCR , 2005, Acta Pharmacologica Sinica.
[43] S. Kitagawa,et al. Effects of dietary chemopreventive phytochemicals on P-glycoprotein function. , 2005, Biochemical and biophysical research communications.
[44] S. Ambudkar,et al. Biochemical mechanism of modulation of human P-glycoprotein (ABCB1) by curcumin I, II, and III purified from Turmeric powder. , 2004, Biochemical pharmacology.
[45] P. Limtrakul,et al. Modulation of human multidrug-resistance MDR-1 gene by natural curcuminoids , 2004, BMC Cancer.
[46] K. Linton,et al. An atomic detail model for the human ATP binding cassette transporter P‐glycoprotein derived from disulphide cross‐ linking and homology modeling , 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[47] Shuzhong Zhang,et al. Effects of the Flavonoids Biochanin A, Morin, Phloretin, and Silymarin on P-Glycoprotein-Mediated Transport , 2003, Journal of Pharmacology and Experimental Therapeutics.
[48] S. Ambudkar,et al. Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells. , 2002, Biochemical pharmacology.
[49] M. Liscovitch,et al. Cancer multidrug resistance: a review of recent drug discovery research. , 2002, IDrugs : the investigational drugs journal.
[50] L. Mayer,et al. Modulation of P-glycoprotein (PGP) mediated multidrug resistance (MDR) using chemosensitizers: recent advances in the design of selective MDR modulators. , 2001, Current medicinal chemistry. Anti-cancer agents.
[51] S. Jee,et al. Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions. , 2001, Anticancer Research.
[52] L. Mayer,et al. Multidrug resistance (MDR) in cancer. Mechanisms, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs. , 2000, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[53] D. Dickson. The story so far… , 2000, Nature.
[54] A. di Pietro,et al. Flavonoids: a class of modulators with bifunctional interactions at vicinal ATP- and steroid-binding sites on mouse P-glycoprotein. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[55] T. A. Beek. Bioactive natural products - detection, isolation and structural determination. , 1997 .
[56] J. Weinstein,et al. Inhibition of human immunodeficiency virus type-1 integrase by curcumin. , 1995, Biochemical pharmacology.
[57] Dong Xu,et al. P-gp upregulation may be blocked by natural curcuminoids, a novel class of chemoresistance-preventing agent. , 2013, Molecular medicine reports.
[58] A. Palmeira,et al. Dual inhibitors of P-glycoprotein and tumor cell growth: (re)discovering thioxanthones. , 2012, Biochemical pharmacology.
[59] P. Limtrakul,et al. Inhibitory effect of curcumin onMDR1 gene expression in patient leukemic cells , 2006, Archives of pharmacal research.
[60] M. Gottesman,et al. Multidrug resistance in cancer: role of ATP–dependent transporters , 2002, Nature Reviews Cancer.
[61] I. Pastan,et al. Biochemical, cellular, and pharmacological aspects of the multidrug transporter. , 1999, Annual review of pharmacology and toxicology.