Association of vitamin D status with serum androgen levels in men

Objective  Studies in rodents indicate a role of vitamin D in male reproduction, but the relationship between vitamin D and androgen levels in men is largely unexplored. We aimed to investigate the association of 25‐hydroxyvitamin D [25(OH)D] levels with testosterone, free androgen index (FAI) and SHBG. Moreover, we examined whether androgen levels show a similar seasonal variation to 25(OH)D.

[1]  G. Nijpels,et al.  Vitamin D and mortality in older men and women , 2009, Clinical endocrinology.

[2]  T. Pieber,et al.  Association of hypovitaminosis D with metabolic disturbances in polycystic ovary syndrome. , 2009, European journal of endocrinology.

[3]  T. Pieber,et al.  Vitamin D status and arterial hypertension: a systematic review , 2009, Nature Reviews Cardiology.

[4]  John J. B. Anderson,et al.  Athletic performance and vitamin D. , 2009, Medicine and science in sports and exercise.

[5]  K. Fujita,et al.  Effect of 1,25-dihydroxyvitamin d on testicular morphology and gene expression in experimental cryptorchid mouse: testis specific cDNA microarray analysis and potential implication in male infertility. , 2009, The Journal of urology.

[6]  邱明才,et al.  Association of vitamin D deficiency with heart failure and sudden cardiac death in a large cross-sectional study of patients referred for coronary angiography , 2009 .

[7]  S. Andò,et al.  Human sperm anatomy: ultrastructural localization of 1α,25‐dihydroxyvitamin D3 receptor and its possible role in the human male gamete , 2008, Journal of anatomy.

[8]  W. März,et al.  Association of vitamin D deficiency with heart failure and sudden cardiac death in a large cross-sectional study of patients referred for coronary angiography. , 2008, The Journal of clinical endocrinology and metabolism.

[9]  G. Riedmüller,et al.  Low Serum Levels of 25-Hydroxyvitamin D Predict Fatal Cancer in Patients Referred to Coronary Angiography , 2008, Cancer Epidemiology Biomarkers & Prevention.

[10]  C. Mathieu,et al.  Vitamin D and human health: lessons from vitamin D receptor null mice. , 2008, Endocrine reviews.

[11]  E. Barrett-Connor,et al.  Low serum testosterone and mortality in older men. , 2008, The Journal of clinical endocrinology and metabolism.

[12]  Sara Gandini,et al.  Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials. , 2007, Archives of internal medicine.

[13]  T. Travison,et al.  The relative contributions of aging, health, and lifestyle factors to serum testosterone decline in men. , 2007, The Journal of clinical endocrinology and metabolism.

[14]  A. Nangia,et al.  Vitamin D receptor found in human sperm. , 2006, Urology.

[15]  L. Mosekilde.  Vitamin D and the elderly , 2005, Clinical endocrinology.

[16]  R. Kumar,et al.  Immunohistochemical detection and distribution of the 1,25-dihydroxyvitamin D3 receptor in rat reproductive tissues , 2005, Histochemistry and Cell Biology.

[17]  Marjolein Visser,et al.  Low vitamin D and high parathyroid hormone levels as determinants of loss of muscle strength and muscle mass (sarcopenia): the Longitudinal Aging Study Amsterdam. , 2003, The Journal of clinical endocrinology and metabolism.

[18]  E. Barrett-Connor,et al.  Seasonal variation of testosterone and waist to hip ratio in men: the Tromsø study. , 2003, The Journal of clinical endocrinology and metabolism.

[19]  N. Skakkebaek,et al.  Variation in levels of serum inhibin B, testosterone, estradiol, luteinizing hormone, follicle-stimulating hormone, and sex hormone-binding globulin in monthly samples from healthy men during a 17-month period: possible effects of seasons. , 2003, The Journal of clinical endocrinology and metabolism.

[20]  S. Resnick,et al.  Longitudinal assessment of serum free testosterone concentration predicts memory performance and cognitive status in elderly men. , 2002, The Journal of clinical endocrinology and metabolism.

[21]  W. März,et al.  Rationale and design of the LURIC study--a resource for functional genomics, pharmacogenomics and long-term prognosis of cardiovascular disease. , 2001, Pharmacogenomics.

[22]  E. Metter,et al.  Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging. , 2001, The Journal of clinical endocrinology and metabolism.

[23]  A. Dobs,et al.  Effects of high-dose simvastatin on adrenal and gonadal steroidogenesis in men with hypercholesterolemia. , 2000, Metabolism: clinical and experimental.

[24]  T. Moriwake,et al.  Vitamin D is an important factor in estrogen biosynthesis of both female and male gonads. , 2000, Endocrinology.

[25]  N. Mauras,et al.  Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright © 1998 by The Endocrine Society Testosterone Deficiency in Young Men: Marked Alterations in Whole Body Protein Kinetics, Strength, and Adiposity* , 2022 .

[26]  G. Andriole,et al.  The effect of finasteride in men with benign prostatic hyperplasia. , 1992, The Journal of urology.

[27]  R C Bruskewitz,et al.  The effect of finasteride in men with benign prostatic hyperplasia. The Finasteride Study Group. , 2002, The New England journal of medicine.

[28]  J. Schenker,et al.  Seasonality in human reproduction: an update. , 1992, Human reproduction.

[29]  F. Habib,et al.  Characterisation of receptors for 1,25-dihydroxyvitamin D3 in the human testis. , 1990, Journal of steroid biochemistry.

[30]  H. DeLuca,et al.  Vitamin D is necessary for reproductive functions of the male rat. , 1989, The Journal of nutrition.

[31]  Walter J. Greenleaf,et al.  The nature of androgen action on male sexuality: a combined laboratory-self-report study on hypogonadal men. , 1983, The Journal of clinical endocrinology and metabolism.

[32]  T. Oppé,et al.  Vitamin D deficiency. , 1979, British medical journal.