Risk factors and correlates of snoring and observed apnea.

BACKGROUND AND PURPOSE Risk factors and correlates of snoring and observed apnea in the population are not well known. This study aimed to assess risk factors and correlates of snoring and observed apnea. METHODS Parents and grandparents of students from 20 randomly selected primary schools in urban and rural areas of Kirikkale, Turkey were asked about respiratory diseases, psychological distress and sleep-related disorders, using the Respiratory Questionnaire, Hospital Anxiety and Depression (HAD) scale and Sleep Questionnaire, respectively, which were returned by their children. RESULTS Out of 13,225 parents and grandparents of primary school students 12,270 returned the questionnaires, for an overall response rate of 92.7%. Snoring and the observed apnea were more prevalent among subjects from rural than those from urban areas (52.6% vs. 46.6%, odds ratio (OR): 1.2, p<0.001 and 16.2% vs. 10.1%, OR: 1.7, p<0.001, respectively). Exposure to biomass smoke and smoking were associated with an increased risk of snoring and observed apnea, after adjusting for gender, age, body mass index, income and education in the multivariate linear model. In all subjects, increases in performance ability, daytime sleepiness, psychological distress and dyspnea scores observed in categories indicating increases in snoring intensity and observed apnea frequency constituted a trend but did always not reach statistical significance. Lastly, prevalence of traffic accidents, falling asleep at the wheel and morning headaches increased with the increments of snoring intensity and apnea frequency. CONCLUSIONS Exposure to biomass smoke in rural areas may account for the higher prevalence of snoring and observed apnea. Snoring intensity and observed apnea frequency may increase prevalence of traffic accidents along with many unfavorable symptoms.

[1]  T. Penzel,et al.  [Snoring and sleep apnea syndrome]. , 1989, Wiener medizinische Wochenschrift.

[2]  T. Ng,et al.  Risk factors associated with habitual snoring and sleep-disordered breathing in a multi-ethnic Asian population: a population-based study. , 2004, Respiratory medicine.

[3]  J. Terán-Santos,et al.  The Association between Sleep Apnea and the Risk of Traffic Accidents , 1999 .

[4]  L. Findley,et al.  Automobile accidents in patients with sleep apnea syndrome. An epidemiological and mechanistic study. , 1998, American journal of respiratory and critical care medicine.

[5]  T. Gislason,et al.  Daytime sleepiness, snoring and gastro‐oesophageal reflux amongst young adults in three European countries , 1995, Journal of internal medicine.

[6]  C. Shapiro,et al.  Snoring, asthma and sleep disturbance in Britain: a community-based survey. , 1993, The European respiratory journal.

[7]  M. Ekici,et al.  Association of asthma-related symptoms with snoring and apnea and effect on health-related quality of life. , 2005, Chest.

[8]  W. Pierson,et al.  Potential adverse health effects of wood smoke. , 1989, The Western journal of medicine.

[9]  T. Young,et al.  Sleep-disordered breathing and motor vehicle accidents in a population-based sample of employed adults. , 1997, Sleep.

[10]  Ullmer,et al.  From snoring to sleep apnea syndrome – clinical spectrum , 2000 .

[11]  G. Maislin,et al.  Physical findings and the risk for obstructive sleep apnea. The importance of oropharyngeal structures. , 2000, American journal of respiratory and critical care medicine.

[12]  D. Teculescu,et al.  Can snoring induce or worsen obstructive sleep apnea? , 1998, Medical hypotheses.

[13]  J. Mauderly,et al.  Health effects of subchronic exposure to low levels of wood smoke in rats. , 2002, Toxicological sciences : an official journal of the Society of Toxicology.

[14]  W. Spitzer,et al.  The influence of psychological status on respiratory symptom reporting. , 1989, The American review of respiratory disease.

[15]  R. Snaith,et al.  The Hospital Anxiety and Depression Scale , 1983 .

[16]  D. Hui,et al.  Prevalence of snoring and sleep-disordered breathing in a student population. , 1999, Chest.

[17]  R G Priest,et al.  Snoring and breathing pauses during sleep: telephone interview survey of a United Kingdom population sample , 1997, BMJ.

[18]  A. V. van Hemert,et al.  Cognitive behavioural therapy for medically unexplained physical symptoms: a randomised controlled trial , 1995, BMJ.

[19]  P. Lloberes,et al.  Self-reported sleepiness while driving as a risk factor for traffic accidents in patients with obstructive sleep apnoea syndrome and in non-apnoeic snorers. , 2000, Respiratory medicine.

[20]  Racionero Casero Má,et al.  The sleep apnea syndrome as a health problem. An estimation of its prevalence and morbimortality , 1999 .

[21]  D. Wetter,et al.  Smoking as a risk factor for sleep-disordered breathing. , 1994, Archives of internal medicine.

[22]  H. Tanzawa,et al.  Contribution of body habitus and craniofacial characteristics to segmental closing pressures of the passive pharynx in patients with sleep-disordered breathing. , 2002, American journal of respiratory and critical care medicine.

[23]  R. Ersu,et al.  Prevalence of snoring and symptoms of sleep-disordered breathing in primary school children in istanbul. , 2004, Chest.

[24]  E V Dunn,et al.  Snoring as a risk factor for disease: an epidemiological survey. , 1985, British medical journal.

[25]  C. George Reduction in motor vehicle collisions following treatment of sleep apnoea with nasal CPAP , 2001, Thorax.

[26]  J. Stradling Epidemiology of snoring and its consequences. , 1995, Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace.

[27]  A. Ellegård,et al.  Cooking fuel smoke and respiratory symptoms among women in low-income areas in Maputo. , 1996 .

[28]  L. Wilhelmsen,et al.  Evaluation of the quality of life of male snorers using the Nottingham Health Profile. , 1998, Acta oto-laryngologica.

[29]  J. Koenig,et al.  Wood smoke: emissions and noncancer respiratory effects. , 1994, Annual review of public health.

[30]  S. Quan,et al.  Risk factors in a general population for snoring. Importance of cigarette smoking and obesity. , 1988, Chest.

[31]  T. Gislason,et al.  The influence of active and passive smoking on habitual snoring. , 2004, American journal of respiratory and critical care medicine.

[32]  Raanan Arens,et al.  Identification of upper airway anatomic risk factors for obstructive sleep apnea with volumetric magnetic resonance imaging. , 2003, American journal of respiratory and critical care medicine.