Mucosa as a route for systemic drug delivery

Amongst the various routes of drug delivery, oral route is perhaps the most preferred to the patient and the clinician alike. Within the oral mucosal cavity, the buccal region offers an attractive route of administration for systemic drug delivery. The mucosa has a rich blood supply and it relatively permeable. The objective of this article is to review mucosa as a route for drug delivery by discussing the structure and environment of the oral mucosa and materials used for oral permeation enhancers.