Cryptic haplotypes of SERPINA1 confer susceptibility to chronic obstructive pulmonary disease

Sally Chappell, Leslie Daly, Kevin Morgan, Tamar Guetta Baranes, Josep Roca, Roberto Rabinovich, Ann Millar, Seamas C. Donnelly, Vera Keatings, William MacNee, Jan Stolk, Pieter Hiemstra, Massimo Miniati, Simonetta Monti, Clare M. O’Connor, and Noor Kalsheker Division of Clinical Chemistry, Molecular Medical Sciences, Institute of Genetics, University Hospital, Queens Medical Centre, University of Nottingham, Nottingham, United Kingdom; Department of Public Health Medicine and Epidemiology, Conway Institute, University College Dublin, Dublin, Ireland; Department of Medicine and Therapeutics, Conway Institute, University College Dublin, Dublin, Ireland; Service de Pneumologia, Hospital Clinic, Hospital Clinico y Provincial de Barcelona, Barcelona, Spain; Lung Research Group, Department of Clinical Science at North Bristol, Southmead Hospital, University of Bristol, Bristol, United Kingdom; Letterkenny General Hospital, Letterkenny, Ireland; Respiratory Medicine, ELEGI Colt Laboratories, University of Edinburgh, Edinburgh, United Kingdom; Department of Pulmonology (C3-P), Leiden University Medical Center, Leiden, The Netherlands; CNR Institute of Clinical Physiology, Pisa, Italy

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