CD8+T cells from a patient with colon carcinoma, specific for a mutant p21-Ras-derived peptide (GLY13→ASP), are cytotoxic towards a carcinoma cell line harbouring the same mutation

[1]  E. Klein,et al.  Expression of the adhesion molecule ICAM-1 and major histocompatibility complex class I antigens on human tumor cells is required for their interaction with autologous lymphocytes in vitro , 2005, Cancer Immunology, Immunotherapy.

[2]  E. Thorsby,et al.  p21‐ras‐peptide‐specific T‐cell responses in a patient with colorectal cancer. CD4+ and CD8+ T cells recognize a peptide corresponding to a common mutation (13Gly → Asp) , 2007, International journal of cancer.

[3]  E. Thorsby,et al.  A K‐ras 13GLY → ASP mutation is recognized by HLA‐DQ7 restricted T cells in a patient with colorectal cancer. Modifying effect of DQ7 on established cancers harbouring this mutation? , 1994, International journal of cancer.

[4]  B. Seliger,et al.  Two tyrosinase nonapeptides recognized on HLA‐A2 melanomas by autologous cytolytic T lymphocytes , 1994, European journal of immunology.

[5]  G. Gaudernack,et al.  K-ras mutation in colorectal cancer: relations to patient age, sex and tumour location. , 1994, British Journal of Cancer.

[6]  G. Gaudernack,et al.  Overlapping epitopes encompassing a point mutation (12 Gly → Arg) in p21 ras can be recognized by HLA‐DR, ‐DP and ‐DQ restricted T cells , 1993, European journal of immunology.

[7]  D. Taub,et al.  Cytotoxic T-cell response and in vivo protection against tumor cells harboring activated ras proto-oncogenes. , 1993, Journal of the National Cancer Institute.

[8]  T. Wölfel,et al.  Lysis of human pancreatic adenocarcinoma cells by autologous hla‐class I‐restricted cytolytic T‐lymphocyte (CTL) clones , 1993, International journal of cancer.

[9]  H. Stauss,et al.  Identification of two cytotoxic T lymphocyte-recognized epitopes in the Ras protein , 1993, The Journal of experimental medicine.

[10]  E. Thorsby,et al.  T cell clones specific for p21 ras‐derived peptides: Characterization of their fine specificity and HLA restriction , 1993, European journal of immunology.

[11]  E. Thorsby,et al.  Memory T cells of a patient with follicular thyroid carcinoma recognize peptides derived from mutated p21 ras (Gln-->Leu61). , 1992, International immunology.

[12]  K. Rock,et al.  Serum proteases alter the antigenicity of peptides presented by class I major histocompatibility complex molecules. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[13]  P. A. Peterson,et al.  Proteasomes are regulated by interferon gamma: implications for antigen processing. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[14]  E. Thorsby,et al.  T-cell responses against products of oncogenes: generation and characterization of human T-cell clones specific for p21 ras-derived synthetic peptides. , 1992, Human immunology.

[15]  H. Schluesener,et al.  Human T lymphocytes recognize a peptide of single point-mutated, oncogenic ras proteins , 1991, The Journal of experimental medicine.

[16]  E. Thorsby,et al.  Distribution of HLA class II alleles among Norwegian Caucasians. , 1990, Human immunology.

[17]  E. E. Gresch Genetic Alterations During Colorectal-Tumor Development , 1989 .

[18]  J. L. Bos,et al.  ras oncogenes in human cancer: a review. , 1989, Cancer research.

[19]  K. Meyer zum Büschenfelde,et al.  Lysis of human melanoma cells by autologous cytolytic T cell clones. Identification of human histocompatibility leukocyte antigen A2 as a restriction element for three different antigens , 1989, The Journal of experimental medicine.

[20]  J. Guillem,et al.  Rapid detection of ras oncogenes in human tumors: applications to colon, esophageal, and gastric cancer. , 1989, Oncogene.

[21]  Y. Nakamura,et al.  Genetic alterations during colorectal-tumor development. , 1988, The New England journal of medicine.

[22]  E. Thorsby,et al.  HLA class I and II typing using cells positively selected from blood by immunomagnetic isolation--a fast and reliable technique. , 2008, Tissue antigens.

[23]  E. Thorsby,et al.  Isolation of pure functionally active CD8+ T cells. Positive selection with monoclonal antibodies directly conjugated to monosized magnetic microspheres. , 1986, Journal of immunological methods.