Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma
暂无分享,去创建一个
Yusuke Nakamura | Hiroshi Kawaguchi | Akira Myoui | Koichi Matsuda | Hirotaka Kawano | Kazuhito Morioka | Kozo Nakamura | Yusuke Nakamura | T. Katagiri | C. Tanikawa | K. Matsuda | N. Naka | K. Ochi | H. Kawaguchi | Y. Daigo | I. Kudawara | A. Myoui | Kozo Nakamura | Toyomasa Katagiri | Yataro Daigo | Hideki Yoshikawa | Hiroumi Yoshikawa | H. Kawano | M. Ieguchi | Chizu Tanikawa | Kensuke Ochi | Norifumi Naka | N. Araki | Ikuo Kudawara | Makoto Ieguchi | K. Morioka | N. Araki | Kazuhito Morioka
[1] M. Gebhardt,et al. Survival Data for 648 Patients with Osteosarcoma Treated at One Institution , 2004, Clinical orthopaedics and related research.
[2] M. Ladanyi,et al. MDM2 gene amplification in metastatic osteosarcoma. , 1993, Cancer research.
[3] S. Jeffery,et al. One gene, two phenotypes: ROR2 mutations in autosomal recessive Robinow syndrome and autosomal dominant brachydactyly type B , 2003, Human mutation.
[4] P. Choong,et al. Downregulation of uPAR confirms link in growth and metastasis of osteosarcoma , 2006, Clinical & Experimental Metastasis.
[5] M. Kay,et al. Sarcoma Derived from Cultured Mesenchymal Stem Cells , 2007, Stem cells.
[6] Piero Picci,et al. Prognostic factors for osteosarcoma of the extremity treated with neoadjuvant chemotherapy , 2006, Cancer.
[7] G. Rosen,et al. Preoperative chemotherapy for osteogenic sarcoma: Selection of postoperative adjuvant chemotherapy based on the response of the primary tumor to preoperative chemotherapy , 1982, Cancer.
[8] I. Hiratani,et al. The Xenopus receptor tyrosine kinase Xror2 modulates morphogenetic movements of the axial mesoderm and neuroectoderm via Wnt signaling. , 2002, Development.
[9] Han-Soo Kim,et al. RECK expression in osteosarcoma: correlation with matrix metalloproteinases activation and tumor invasiveness , 2007, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[10] S. Mundlos,et al. A new subtype of brachydactyly type B caused by point mutations in the bone morphogenetic protein antagonist NOGGIN. , 2007, American journal of human genetics.
[11] Yusuke Nakamura,et al. Molecular features of hormone-refractory prostate cancer cells by genome-wide gene expression profiles. , 2007, Cancer research.
[12] B. Alman,et al. Side population cells isolated from mesenchymal neoplasms have tumor initiating potential. , 2007, Cancer research.
[13] M. Longaker,et al. Absence of the p53 tumor suppressor gene promotes osteogenesis in mesenchymal stem cells. , 2006, Journal of pediatric surgery.
[14] R. Gorlick,et al. Chemotherapy resistance in osteosarcoma: current challenges and future directions , 2006, Expert review of anticancer therapy.
[15] P. Meltzer,et al. Biology of childhood osteogenic sarcoma and potential targets for therapeutic development: meeting summary. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.
[16] C. Rodríguez-Galindo,et al. Metastatic osteosarcoma , 2006 .
[17] D. Mercola,et al. The proto-oncogene c-fos is over-expressed in the majority of human osteosarcomas. , 1990, Oncogene.
[18] Bhabatosh Chaudhuri,et al. Protein kinases as targets for anticancer agents: from inhibitors to useful drugs. , 2002, Pharmacology & therapeutics.
[19] A. Mock,et al. c-myc amplification and expression in newly established human osteosarcoma cell lines. , 1987, Cancer research.
[20] C. Rodríguez-Galindo,et al. Metastatic osteosarcoma. , 2020, Cancer.
[21] Y. Andéol,et al. A c-ras-Ki oncogene is activated, amplified and overexpressed in a human osteosarcoma cell line. , 1987, Biochemical and biophysical research communications.
[22] R. Nusse,et al. Mechanisms of Wnt signaling in development. , 1998, Annual review of cell and developmental biology.
[23] Stefan Mundlos,et al. Modulation of GDF5/BRI‐b signalling through interaction with the tyrosine kinase receptor Ror2 , 2004, Genes to cells : devoted to molecular & cellular mechanisms.
[24] Yusuke Nakamura,et al. Frequent β‐Catenin Abnormalities in Bone and Soft‐tissue Tumors , 1999, Japanese journal of cancer research : Gann.
[25] Stephen M Hewitt,et al. The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis , 2004, Nature Medicine.
[26] S. Ferrari,et al. Evaluation of P‐glycoprotein, HER‐2/ErbB‐2, p53, and Bcl‐2 in primary tumor and metachronous lung metastases in patients with high‐grade osteosarcoma , 2004, Cancer.
[27] W Russe,et al. [Osteogenic sarcoma]. , 1983, ZFA. Zeitschrift fur Allgemeinmedizin.
[28] W. Forrester. The Ror receptor tyrosine kinase family , 2002, Cellular and Molecular Life Sciences CMLS.
[29] T Tanaka,et al. Identification by cDNA microarray of genes involved in ovarian carcinogenesis. , 2000, Cancer research.
[30] S. Ferrari,et al. Adjuvant and neoadjuvant combination chemotherapy for osteogenic sarcoma , 2007, Current opinion in oncology.
[31] G. Tortora,et al. Key cancer cell signal transduction pathways as therapeutic targets. , 2006, European journal of cancer.
[32] Baojin Fu,et al. Accumulated Chromosomal Instability in Murine Bone Marrow Mesenchymal Stem Cells Leads to Malignant Transformation , 2006, Stem cells.
[33] M. Pittenger,et al. Multilineage potential of adult human mesenchymal stem cells. , 1999, Science.
[34] Yusuke Nakamura,et al. Genome-wide profiling of gene expression in 29 normal human tissues with a cDNA microarray. , 2002, DNA research : an international journal for rapid publication of reports on genes and genomes.
[35] M. Patton,et al. Recessive Robinow syndrome, allelic to dominant brachydactyly type B, is caused by mutation of ROR2 , 2000, Nature Genetics.
[36] Yusuke Nakamura,et al. Prediction of response to neoadjuvant chemotherapy for osteosarcoma by gene-expression profiles. , 2004, International journal of oncology.
[37] Edward W Scott,et al. Stem-like cells in bone sarcomas: implications for tumorigenesis. , 2005, Neoplasia.
[38] J. Schlessinger. Cell Signaling by Receptor Tyrosine Kinases , 2000, Cell.
[39] H. Tideman. ERbB-2 expression is correlated with poor prognosis for patients with osteosarcoma , 1998 .
[40] S. Burdach,et al. A complex pattern of chemokine receptor expression is seen in osteosarcoma , 2008, BMC Cancer.
[41] B. Komm,et al. The orphan receptor tyrosine kinase Ror2 promotes osteoblast differentiation and enhances ex vivo bone formation. , 2007, Molecular endocrinology.
[42] Yusuke Nakamura,et al. Therapeutic potential of antibodies against FZD10, a cell-surface protein, for synovial sarcomas , 2005, Oncogene.
[43] Y. Furukawa,et al. CDC20, a potential cancer therapeutic target, is negatively regulated by p53 , 2008, Oncogene.
[44] Yusuke Nakamura,et al. Genome-wide analysis of gene expression in synovial sarcomas using a cDNA microarray. , 2002, Cancer research.
[45] P. Choong,et al. A review of clinical and molecular prognostic factors in osteosarcoma , 2008, Journal of Cancer Research and Clinical Oncology.
[46] P. Bodine,et al. The orphan receptor tyrosine kinase Ror2 modulates canonical Wnt signaling in osteoblastic cells. , 2005, Molecular endocrinology.
[47] G. Yancopoulos,et al. Ror2, encoding a receptor-like tyrosine kinase, is required for cartilage and growth plate development , 2000, Nature Genetics.
[48] R. Nusse,et al. Purified Wnt5a Protein Activates or Inhibits β-Catenin–TCF Signaling Depending on Receptor Context , 2006, PLoS biology.
[49] R. Nusse. The Wnt gene family in tumorigenesis and in normal development , 1992, The Journal of Steroid Biochemistry and Molecular Biology.
[50] H. Horiuchi,et al. ErbB‐2 expression is correlated with poor prognosis for patients with osteosarcoma , 1996, Cancer.
[51] F. Bertoni,et al. Ezrin in osteosarcoma: comparison between conventional high-grade and central low-grade osteosarcoma. , 2006, Pathology, research and practice.