PDGF-D Improves Drug Delivery and Efficacy via Vascular Normalization, But Promotes Lymphatic Metastasis by Activating CXCR4 in Breast Cancer
暂无分享,去创建一个
R. Jain | D. Fukumura | W. Kamoun | Lei Xu | S. Liao | K. Naxerova | Yuhui Huang | Rekha Samuel | Jieqiong Liu | Peigen Huang | Tony Shi
[1] Zhiwei Wang,et al. RETRACTED ARTICLE: Platelet-derived growth factor-D contributes to aggressiveness of breast cancer cells by up-regulating Notch and NF-κB signaling pathways , 2011, Breast Cancer Research and Treatment.
[2] R. Jain,et al. Delivering nanomedicine to solid tumors , 2010, Nature Reviews Clinical Oncology.
[3] Zhiwei Wang,et al. 3,3'-Diindolylmethane enhances taxotere-induced apoptosis in hormone-refractory prostate cancer cells through survivin down-regulation. , 2009, Cancer research.
[4] Rakesh K. Jain,et al. PDGF-C Induces Maturation of Blood Vessels in a Model of Glioblastoma and Attenuates the Response to Anti-VEGF Treatment , 2009, PloS one.
[5] I. Kasman,et al. PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment. , 2009, Cancer cell.
[6] T. Sanke,et al. Cytoplasmic CXCR4 expression in breast cancer: induction by nitric oxide and correlation with lymph node metastasis and poor prognosis , 2008, BMC Cancer.
[7] Zhiwei Wang,et al. Mammalian target of rapamycin repression by 3,3'-diindolylmethane inhibits invasion and angiogenesis in platelet-derived growth factor-D-overexpressing PC3 cells. , 2008, Cancer research.
[8] Zhiwei Wang,et al. Down-regulation of platelet-derived growth factor-D inhibits cell growth and angiogenesis through inactivation of notch-1 and nuclear factor-κB signaling , 2007 .
[9] T. Vrekoussis,et al. Expression of endothelial PDGF receptors α and β in breast cancer: Up-regulation of endothelial PDGF receptor β , 2007 .
[10] T. Vrekoussis,et al. Expression of endothelial PDGF receptors alpha and beta in breast cancer: up-regulation of endothelial PDGF receptor beta. , 2007, Oncology Report.
[11] Dai Fukumura,et al. Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: therapeutic implications. , 2006, Cancer research.
[12] Kathryn E Luker,et al. Functions of CXCL12 and CXCR4 in breast cancer. , 2006, Cancer letters.
[13] C. Cordon-Cardo,et al. Autocrine PDGFR signaling promotes mammary cancer metastasis. , 2006, The Journal of clinical investigation.
[14] Ricky T. Tong,et al. Placenta growth factor overexpression inhibits tumor growth, angiogenesis, and metastasis by depleting vascular endothelial growth factor homodimers in orthotopic mouse models. , 2006, Cancer research.
[15] G. Watkins,et al. The elevated level of CXCR4 is correlated with nodal metastasis of human breast cancer. , 2005, Breast.
[16] R. Jain. Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic Therapy , 2005, Science.
[17] Manuel Hidalgo,et al. Matrix metalloproteinase-2 contributes to cancer cell migration on collagen. , 2005, Cancer research.
[18] Ricky T. Tong,et al. Blocking platelet-derived growth factor-D/platelet-derived growth factor receptor beta signaling inhibits human renal cell carcinoma progression in an orthotopic mouse model. , 2005, Cancer research.
[19] Robert D. Goldman,et al. Live Cell Imaging: A Laboratory Manual , 2004 .
[20] Toshio Ohhashi,et al. PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis. , 2004, Cancer cell.
[21] Rakesh K. Jain,et al. Vascular Normalization by Vascular Endothelial Growth Factor Receptor 2 Blockade Induces a Pressure Gradient Across the Vasculature and Improves Drug Penetration in Tumors , 2004, Cancer Research.
[22] H. Kim,et al. A Potential Oncogenic Activity of Platelet-Derived Growth Factor D in Prostate Cancer Progression , 2004, Cancer Research.
[23] D. Fukumura,et al. Hypoxia-Induced Activation of p38 Mitogen-Activated Protein Kinase and Phosphatidylinositol 3′-Kinase Signaling Pathways Contributes to Expression of Interleukin 8 in Human Ovarian Carcinoma Cells , 2004, Clinical Cancer Research.
[24] M. F. Booth,et al. What brings pericytes to tumor vessels? , 2003, The Journal of clinical investigation.
[25] Rakesh K Jain,et al. Molecular regulation of vessel maturation , 2003, Nature Medicine.
[26] Xuri Li,et al. PDGF-D is a potent transforming and angiogenic growth factor , 2003, Oncogene.
[27] Tobias Sjöblom,et al. Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy. , 2002, Cancer research.
[28] C. Quinn,et al. Angiogenesis, thrombospondin, and ductal carcinoma in situ of the breast , 2002, Journal of clinical pathology.
[29] M. Jeffers,et al. Platelet-derived growth factor D: tumorigenicity in mice and dysregulated expression in human cancer. , 2002, Cancer research.
[30] J. Rothberg,et al. PDGF-D, a new protease-activated growth factor , 2001, Nature Cell Biology.
[31] C. Heldin,et al. PDGF-D is a specific, protease-activated ligand for the PDGF β-receptor , 2001, Nature Cell Biology.
[32] T. Mcclanahan,et al. Involvement of chemokine receptors in breast cancer metastasis , 2001, Nature.
[33] C. Heldin,et al. PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor. , 2001, Nature cell biology.
[34] C. Heldin,et al. PDGF-C is a new protease-activated ligand for the PDGF α-receptor , 2000, Nature Cell Biology.
[35] J. Wood,et al. Inhibition of malignant ascites and growth of human ovarian carcinoma by oral administration of a potent inhibitor of the vascular endothelial growth factor receptor tyrosine kinases. , 2000, International journal of oncology.
[36] H Li,et al. PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor. , 2000, Nature cell biology.
[37] Anthony J. Guidi,et al. Vascular stroma formation in carcinoma in situ, invasive carcinoma, and metastatic carcinoma of the breast. , 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.
[38] David R. Kaplan,et al. Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt , 1997, Science.
[39] K. Hirschi,et al. Pericytes in the microvasculature. , 1996, Cardiovascular research.
[40] A. Gown,et al. Expression of platelet-derived growth factor B-chain and the platelet-derived growth factor receptor beta subunit in human breast tissue and breast carcinoma. , 1995, Cancer research.
[41] A. Gown,et al. Expression of platelet-derived growth factor B-chain and the platelet-derived growth factor receptor beta subunit in human breast tissue and breast carcinoma. , 1995, Cancer research.