Proteins of the Myc network: essential regulators of cell growth and differentiation.

[1]  M. Hampsey.  A SAGA of histone acetylation and gene expression. , 1997, Trends in genetics : TIG.

[2]  M. Barone,et al.  Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src , 1995, Nature.

[3]  M. Cole,et al.  Mouse and rat B-myc share amino acid sequence homology with the c-myc transcriptional activator domain and contain a B-myc specific carboxy terminal region. , 1995, Oncogene.

[4]  M. Eilers,et al.  Expression of cyclin D1 mRNA is not upregulated by Myc in rat fibroblasts. , 1995, Oncogene.

[5]  N. Copeland,et al.  Mad3 and Mad4: novel Max‐interacting transcriptional repressors that suppress c‐myc dependent transformation and are expressed during neural and epidermal differentiation. , 1995, The EMBO journal.

[6]  M. Roussel,et al.  Signaling by ABL oncogenes through cyclin D1. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[7]  F. Watt,et al.  Changes in expression of members of the fos and jun families and myc network during terminal differentiation of human keratinocytes. , 1995, Oncogene.

[8]  M. Pagano,et al.  Identification of a Myc‐dependent step during the formation of active G1 cyclin‐cdk complexes. , 1995, The EMBO journal.

[9]  M. Méchali,et al.  Selective and rapid nuclear translocation of a c-Myc-containing complex after fertilization of Xenopus laevis eggs , 1995, Molecular and cellular biology.

[10]  F. Kaye,et al.  The N-terminal domain of c-Myc associates with alpha-tubulin and microtubules in vivo and in vitro , 1995, Molecular and cellular biology.

[11]  G. Hart,et al.  c-Myc Is Glycosylated at Threonine 58, a Known Phosphorylation Site and a Mutational Hot Spot in Lymphomas (*) , 1995, The Journal of Biological Chemistry.

[12]  P. Beer-Romero,et al.  Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. , 1995, Science.

[13]  C. Seelos,et al.  Differential effects by Mad and Max on transformation by cellular and viral oncoproteins. , 1995, Oncogene.

[14]  M. Raffeld,et al.  A link between increased transforming activity of lymphoma-derived MYC mutant alleles, their defective regulation by p107, and altered phosphorylation of the c-Myc transactivation domain , 1995, Molecular and cellular biology.

[15]  M. Roussel,et al.  Rescue of defective mitogenic signaling by D-type cyclins. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[16]  E. Ziff,et al.  The nerve growth factor-responsive PC12 cell line does not express the Myc dimerization partner Max , 1995, Molecular and cellular biology.

[17]  R. DePinho,et al.  Effects of the MYC oncogene antagonist, MAD, on proliferation, cell cycling and the malignant phenotype of human brain tumour cells , 1995, Nature Medicine.

[18]  A. Berns,et al.  Proviral tagging in E mu‐myc transgenic mice lacking the Pim‐1 proto‐oncogene leads to compensatory activation of Pim‐2. , 1995, The EMBO journal.

[19]  R. Eisenman,et al.  Repression of Myc-Ras cotransformation by Mad is mediated by multiple protein-protein interactions. , 1995, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[20]  D. Lallemand,et al.  Specific c-myc and max regulation in epithelial cells. , 1995, Oncogene.

[21]  G. Hart,et al.  Glycosylation of the c-Myc transactivation domain. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[22]  P. Farnham,et al.  An E-box-mediated increase in cad transcription at the G1/S-phase boundary is suppressed by inhibitory c-Myc mutants , 1995, Molecular and cellular biology.

[23]  J. León,et al.  Differential regulation of Max and role of c-Myc during erythroid and myelomonocytic differentiation of K562 cells. , 1995, Oncogene.

[24]  Mark J Alkema,et al.  Transformation of axial skeleton due to overexpression of bmi-1 in transgenic mice , 1995, Nature.

[25]  S. Triezenberg,et al.  Structure and function of transcriptional activation domains. , 1995, Current opinion in genetics & development.

[26]  S Gaubatz,et al.  Transcriptional activation by Myc is under negative control by the transcription factor AP‐2. , 1995, The EMBO journal.

[27]  M. Méchali,et al.  Analysis of c-Myc and Max binding to the c-myc promoter: evidence that autosuppression occurs via an indirect mechanism. , 1995, Oncogene.

[28]  C. Thompson,et al.  Apoptosis in the pathogenesis and treatment of disease , 1995, Science.

[29]  H. Steller.  Mechanisms and genes of cellular suicide , 1995, Science.

[30]  R. Eisenman,et al.  Mad-max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3 , 1995, Cell.

[31]  L. Chin,et al.  An amino-terminal domain of Mxi1 mediates anti-myc oncogenic activity and interacts with a homolog of the Yeast Transcriptional Repressor SIN3 , 1995, Cell.

[32]  D. Livingston,et al.  A family of transcriptional adaptor proteins targeted by the E1A oncoprotein , 1995, Nature.

[33]  K. Alitalo,et al.  Expression of the mad gene during cell differentiation in vivo and its inhibition of cell growth in vitro , 1995, The Journal of cell biology.

[34]  R. Eisenman,et al.  Overexpressed max is not oncogenic and attenuates myc-induced lymphoproliferation and lymphomagenesis in transgenic mice. , 1995, Oncogene.

[35]  A. Nordheim,et al.  Signal integration at the c-fos promoter. , 1995, Carcinogenesis.

[36]  D. Brough,et al.  An essential domain of the c-myc protein interacts with a nuclear factor that is also required for E1A-mediated transformation , 1995, Molecular and cellular biology.

[37]  Arthur R. Brothman,et al.  Mutation of the MXI1 gene in prostate cancer , 1995, Nature Genetics.

[38]  S. Korsmeyer.  Regulators of cell death. , 1995, Trends in genetics : TIG.

[39]  L. Wolff,et al.  Acceleration of apoptosis in transforming growth factor beta 1-treated M1 cells ectopically expressing B-myb. , 1995, Cancer research.

[40]  R. Kingston,et al.  Identification of a cDNA for SSRP1, an HMG-box protein, by interaction with the c-Myc oncoprotein in a novel bacterial expression screen. , 1995, Nucleic acids research.

[41]  P. Robbins,et al.  The retinoblastoma susceptibility gene product regulates Myc-mediated transcription. , 1995, Oncogene.

[42]  R. DePinho,et al.  Inhibition of ras-induced proliferation and cellular transformation by p16INK4 , 1995, Science.

[43]  R. Craig,et al.  Mcl-1, a member of the Bcl-2 family, delays apoptosis induced by c-Myc overexpression in Chinese hamster ovary cells. , 1994, Cancer research.

[44]  D. Reisman,et al.  Transactivation of the human p53 tumor suppressor gene by c-Myc/Max contributes to elevated mutant p53 expression in some tumors , 1994, Molecular and cellular biology.

[45]  N. Hay,et al.  Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1. , 1994, Genes & development.

[46]  D. Green,et al.  Functional Myc-Max heterodimer is required for activation-induced apoptosis in T cell hybridomas , 1994, The Journal of experimental medicine.

[47]  W. Lee,et al.  Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis , 1994, Molecular and cellular biology.

[48]  L. M. Facchini,et al.  Myc induces cyclin D1 expression in the absence of de novo protein synthesis and links mitogen-stimulated signal transduction to the cell cycle. , 1994, Oncogene.

[49]  D. Gillespie,et al.  c-Myc inhibits myogenic differentiation and myoD expression by a mechanism which can be dissociated from cell transformation. , 1994, Oncogene.

[50]  T. Hunter,et al.  Cyclins and cancer II: Cyclin D and CDK inhibitors come of age , 1994, Cell.

[51]  C. Sherr.  G1 phase progression: Cycling on cue , 1994, Cell.

[52]  D. Housman,et al.  p53 status and the efficacy of cancer therapy in vivo. , 1994, Science.

[53]  K. Alitalo,et al.  c‐Myc induces cellular susceptibility to the cytotoxic action of TNF‐alpha. , 1994, The EMBO journal.

[54]  H. Hermeking,et al.  Role of c-myc in simian virus 40 large tumor antigen-induced DNA synthesis in quiescent 3T3-L1 mouse fibroblasts. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[55]  R. Sears,et al.  The alternatively initiated c-Myc proteins differentially regulate transcription through a noncanonical DNA-binding site. , 1994, Genes & development.

[56]  D. Reinberg,et al.  Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53 , 1994, Molecular and cellular biology.

[57]  H. Hermeking,et al.  Mediation of c-Myc-induced apoptosis by p53. , 1994, Science.

[58]  C. Harris,et al.  Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. , 1994, Cancer research.

[59]  F. Cope,et al.  Apoptosis II: The Molecular Basis of Apoptosis in Disease , 1994 .

[60]  J. Cleveland,et al.  Ornithine decarboxylase is a mediator of c-Myc-induced apoptosis , 1994, Molecular and cellular biology.

[61]  G. Prendergast,et al.  c‐Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II. , 1994, The EMBO journal.

[62]  A. Porter,et al.  Nuclear c-Myc plays an important role in the cytotoxicity of tumor necrosis factor alpha in tumor cells , 1994, Molecular and cellular biology.

[63]  E. Prochownik,et al.  Assignment of the human MAD and MXI1 genes to chromosomes 2p12-p13 and 10q24-q25. , 1994, Genomics.

[64]  J. Sedivy,et al.  Effects of c-myc expression on cell cycle progression , 1994, Molecular and cellular biology.

[65]  Liang Zhu,et al.  Interaction of c‐Myc with the pRb‐related protein p107 results in inhibition of c‐Myc‐mediated transactivation. , 1994, The EMBO journal.

[66]  J. Frost,et al.  c-Myc cooperates with activated Ras to induce the cdc2 promoter , 1994, Molecular and cellular biology.

[67]  D. Fisher.  Apoptosis in cancer therapy: Crossing the threshold , 1994, Cell.

[68]  Y. Miyagi,et al.  The s-Myc protein having the ability to induce apoptosis is selectively expressed in rat embryo chondrocytes. , 1994, Oncogene.

[69]  B. Lutterbach,et al.  Hierarchical phosphorylation at N-terminal transformation-sensitive sites in c-Myc protein is regulated by mitogens and in mitosis , 1994, Molecular and cellular biology.

[70]  C. Cultraro,et al.  Regulation of murine Max (Myn) parallels the regulation of c-Myc in differentiating murine erythroleukemia cells. , 1994, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[71]  H. Lovec,et al.  Cyclin D1/bcl‐1 cooperates with myc genes in the generation of B‐cell lymphoma in transgenic mice. , 1994, The EMBO journal.

[72]  M. Karin,et al.  Activation of cAMP and mitogen responsive genes relies on a common nuclear factor , 1994, Nature.

[73]  Michael R. Green,et al.  Nuclear protein CBP is a coactivator for the transcription factor CREB , 1994, Nature.

[74]  D. Bergstrom,et al.  Participation of cyclin A in Myc-induced apoptosis. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[75]  G. Evan,et al.  c‐Myc‐induced apoptosis in fibroblasts is inhibited by specific cytokines. , 1994, The EMBO journal.

[76]  W. Schaffner,et al.  A minimal transcription activation domain consisting of a specific array of aspartic acid and leucine residues. , 1994, Biological chemistry Hoppe-Seyler.

[77]  M. Raffeld,et al.  Mutations in the coding region of c-MYC in AIDS-associated and other aggressive lymphomas. , 1994, Cancer research.

[78]  E. Lalli,et al.  Signal transduction and gene regulation: the nuclear response to cAMP. , 1994, The Journal of biological chemistry.

[79]  R. DePinho,et al.  Suppression of Myc, but not E1a, transformation activity by Max-associated proteins, Mad and Mxi1. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[80]  H. Pan,et al.  Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development. , 1994, Genes & development.

[81]  S Gaubatz,et al.  An E-box element localized in the first intron mediates regulation of the prothymosin alpha gene by c-myc , 1994, Molecular and cellular biology.

[82]  A. Saltiel,et al.  c-Myc Does Not Require Max for Transcriptional Activity in PC-12 Cells , 1994, Molecular and Cellular Neuroscience.

[83]  K. Alitalo,et al.  Repression of cyclin D1: a novel function of MYC. , 1994, Molecular and cellular biology.

[84]  D. Wechsler,et al.  Localization of the human Mxi1 transcription factor gene (MXI1) to chromosome 10q24-q25. , 1994, Genomics.

[85]  R. Tjian,et al.  TBP-TAF complexes: selectivity factors for eukaryotic transcription. , 1994, Current opinion in cell biology.

[86]  S. Gustincich,et al.  Dissection of c-myc domains involved in S phase induction of NIH3T3 fibroblasts. , 1994, Oncogene.

[87]  D. Albert,et al.  Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53. , 1994, Genes & development.

[88]  L. M. Facchini,et al.  Dysfunction of the Myc-induced apoptosis mechanism accompanies c-myc activation in the tumorigenic L929 cell line. , 1994, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[89]  R. Eisenman,et al.  Functional analysis of the AUG- and CUG-initiated forms of the c-Myc protein. , 1994, Molecular biology of the cell.

[90]  Y. H. Kim,et al.  Up-regulation of c-myc induces the gene expression of the murine homologues of p34cdc2 and cyclin-dependent kinase-2 in T lymphocytes. , 1994, Journal of immunology.

[91]  J.M. Adams,et al.  Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene. , 1994, The EMBO journal.

[92]  C. Sawyers,et al.  Differential complementation of Bcr-Abl point mutants with c-Myc. , 1994, Science.

[93]  C. Dang,et al.  Binding and suppression of the Myc transcriptional activation domain by p107. , 1994, Science.

[94]  L. Larsson,et al.  Expression of mad, mxi1, max and c-myc during induced differentiation of hematopoietic cells: opposite regulation of mad and c-myc. , 1994, Oncogene.

[95]  John Calvin Reed,et al.  The novel primary response gene MyD118 and the proto-oncogenes myb, myc, and bcl-2 modulate transforming growth factor beta 1-induced apoptosis of myeloid leukemia cells. , 1994, Molecular and cellular biology.

[96]  M. Sofroniew,et al.  Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene. , 1994, Genes & development.

[97]  F. Sablitzky,et al.  The expression pattern of Id4, a novel dominant negative helix-loop-helix protein, is distinct from Id1, Id2 and Id3. , 1994, Nucleic acids research.

[98]  David L. Vaux,et al.  An evolutionary perspective on apoptosis , 1994, Cell.

[99]  K. Alitalo,et al.  Max activity is affected by phosphorylation at two NH2-terminal sites. , 1994, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[100]  D. Green,et al.  BCR-ABL Maintains Resistance of Chronic Myelogenous Leukemia Cells to Apoptotic Cell Death , 1994 .

[101]  D. Eick,et al.  Ongoing mutations in the N-terminal domain of c-Myc affect transactivation in Burkitt's lymphoma cell lines. , 1994, Oncogene.

[102]  S. Maheswaran,et al.  Intracellular association of the protein product of the c-myc oncogene with the TATA-binding protein , 1994, Molecular and cellular biology.

[103]  G. Evan,et al.  Oncogenes and cell death. , 1994, Current opinion in genetics & development.

[104]  M. Roussel,et al.  Dual control of myc expression through a single DNA binding site targeted by ets family proteins and E2F-1. , 1994, Oncogene.

[105]  R. Brent,et al.  Mapping of two genes encoding members of a distinct subfamily of MAX interacting proteins: MAD to human chromosome 2 and mouse chromosome 6, and MXI1 to human chromosome 10 and mouse chromosome 19. , 1994, Oncogene.

[106]  E. Taparowsky,et al.  Structural analysis of the chicken max gene. , 1994, Oncogene.

[107]  R. Weinberg,et al.  Function of a human cyclin gene as an oncogene. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[108]  R. Weinberg,et al.  Tumor spectrum analysis in p53-mutant mice , 1994, Current Biology.

[109]  John Calvin Reed.  Bcl-2 and the regulation of programmed cell death , 1994, The Journal of cell biology.

[110]  S. Goff,et al.  Inhibition of transcriptional regulator Yin-Yang-1 by association with c-Myc. , 1993, Science.

[111]  C. Gregory,et al.  Apoptosis in Burkitt lymphoma cells is driven by c-myc. , 1993, Oncogene.

[112]  D. Gillespie,et al.  Transcription activation by Myc and Max: flanking sequences target activation to a subset of CACGTG motifs in vivo. , 1993, The EMBO journal.

[113]  M. Henriksson,et al.  Identification of casein kinase II phosphorylation sites in Max: effects on DNA-binding kinetics of Max homo- and Myc/Max heterodimers. , 1993, Oncogene.

[114]  G. Klein,et al.  Phosphorylation sites mapping in the N-terminal domain of c-myc modulate its transforming potential. , 1993, Oncogene.

[115]  N. Sonenberg,et al.  Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E , 1993, Molecular and cellular biology.

[116]  G. Evan,et al.  The c‐Myc protein induces cell cycle progression and apoptosis through dimerization with Max. , 1993, The EMBO journal.

[117]  B. Amati,et al.  Distinct DNA binding preferences for the c-Myc/Max and Max/Max dimers. , 1993, Nucleic acids research.

[118]  J. Trent,et al.  WAF1, a potential mediator of p53 tumor suppression , 1993, Cell.

[119]  A. Grzeschiczek,et al.  Expression of a Pim-1 transgene accelerates lymphoproliferation and inhibits apoptosis in lpr/lpr mice. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[120]  N. Hay,et al.  c-Myc induces the expression and activity of ornithine decarboxylase. , 1993, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[121]  P. Laird,et al.  Pim-1 levels determine the size of early B lymphoid compartments in bone marrow , 1993, The Journal of experimental medicine.

[122]  R. Eisenman,et al.  A switch from Myc:Max to Mad:Max heterocomplexes accompanies monocyte/macrophage differentiation. , 1993, Genes & development.

[123]  I. Weissman,et al.  Neither macromolecular synthesis nor myc is required for cell death via the mechanism that can be controlled by Bcl-2 , 1993, Molecular and cellular biology.

[124]  B. Barres,et al.  Programmed cell death and the control of cell survival: lessons from the nervous system. , 1993, Science.

[125]  S. Korsmeyer,et al.  Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair , 1993, Cell.

[126]  P. Laird,et al.  In vivo analysis of Pim-1 deficiency. , 1993, Nucleic acids research.

[127]  M. Groudine,et al.  Common mechanisms for the control of eukaryotic transcriptional elongation , 1993, BioEssays : news and reviews in molecular, cellular and developmental biology.

[128]  M. Raffeld,et al.  Clustered mutations in the second exon of the MYC gene in sporadic Burkitt's lymphoma. , 1993, Oncogene.

[129]  R. Roeder,et al.  Direct role for Myc in transcription initiation mediated by interactions with TFII-I , 1993, Nature.

[130]  C. Molina,et al.  Adrenergic signals direct rhythmic expression of transcriptional represser CREM in the pineal gland , 1993, Nature.

[131]  M. Rowe,et al.  Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[132]  L. J. Veer,et al.  TATA-binding protein and the retinoblastoma gene product bind to overlapping epitopes on c-Myc and adenovirus E1A protein. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[133]  I. Magrath,et al.  Point mutations in the c–Myc transactivation domain are common in Burkitt's lymphoma and mouse plasmacytomas , 1993, Nature Genetics.

[134]  A Ma,et al.  Binding of myc proteins to canonical and noncanonical DNA sequences , 1993, Molecular and cellular biology.

[135]  P. Laird,et al.  Impaired interleukin-3 response in Pim-1-deficient bone marrow-derived mast cells. , 1993, Blood.

[136]  E. Thompson,et al.  Suppression of c-myc is a critical step in glucocorticoid-induced human leukemic cell lysis. , 1993, The Journal of biological chemistry.

[137]  R. Mohammad,et al.  Prothymosin alpha gene expression correlates with proliferation, not differentiation, of HL-60 cells. , 1993, Blood.

[138]  J L Cleveland,et al.  The ornithine decarboxylase gene is a transcriptional target of c-Myc. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[139]  Peter F. Johnson,et al.  Activation domains of transcriptional regulatory proteins , 1993 .

[140]  K. Isselbacher,et al.  Increased expression of eukaryotic translation initiation factors eIF-4E and eIF-2 alpha in response to growth induction by c-myc. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[141]  D. Gillespie,et al.  Gene-regulatory properties of Myc helix-loop-helix/leucine zipper mutants: Max-dependent DNA binding and transcriptional activation in yeast correlates with transforming capacity. , 1993, Oncogene.

[142]  K. Wiman.  The retinoblastoma gene: role in cell cycle control and cell differentiation , 1993, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[143]  J A Moshier,et al.  Transformation of NIH/3T3 cells by ornithine decarboxylase overexpression. , 1993, Cancer research.

[144]  Stephen K. Burley,et al.  Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain , 1993, Nature.

[145]  R. DePinho,et al.  Zebra fish myc family and max genes: differential expression and oncogenic activity throughout vertebrate evolution , 1993, Molecular and cellular biology.

[146]  C. Cultraro,et al.  Transfected wild-type and mutant max regulate cell growth and differentiation of murine erythroleukemia cells. , 1993, Oncogene.

[147]  B. S. Yang,et al.  Overexpression of Myc suppresses CCAAT transcription factor/nuclear factor 1-dependent promoters in vivo , 1993, Molecular and cellular biology.

[148]  M. Kastan,et al.  Altered cytoplasmic/nuclear distribution of the c-myc protein in differentiating ML-1 human myeloid leukemia cells. , 1993, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[149]  R. Davis,et al.  Transactivation of gene expression by Myc is inhibited by mutation at the phosphorylation sites Thr-58 and Ser-62. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[150]  M. Pagano,et al.  Differential modulation of cyclin gene expression by MYC. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[151]  R. Craig,et al.  MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[152]  H. Mischak,et al.  Addition of constitutive c-myc expression to Abelson murine leukemia virus changes the phenotype of the cells transformed by the virus from pre-B-cell lymphomas to plasmacytomas , 1993, Molecular and cellular biology.

[153]  W. Gu,et al.  Opposite regulation of gene transcription and cell proliferation by c-Myc and Max. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[154]  K. Isselbacher,et al.  A dominant-negative mutant of Max that inhibits sequence-specific DNA binding by Myc proteins. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[155]  A. Bradley,et al.  A null c-myc mutation causes lethality before 10.5 days of gestation in homozygotes and reduced fertility in heterozygous female mice. , 1993, Genes & development.

[156]  N. Hay,et al.  Myc-mediated apoptosis is blocked by ectopic expression of Bcl-2 , 1993, Molecular and cellular biology.

[157]  L. T. Peltenburg,et al.  Downregulation of HLA class I expression by c-myc in human melanoma is independent of enhancer A. , 1993, Nucleic acids research.

[158]  H. Wang,et al.  Transcriptional repression in Saccharomyces cerevisiae by a SIN3-LexA fusion protein , 1993, Molecular and cellular biology.

[159]  J. Sedivy,et al.  Effects of c-myc expression on proliferation, quiescence, and the G0 to G1 transition in nontransformed cells. , 1993, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[160]  C. Dang,et al.  B-myc inhibits neoplastic transformation and transcriptional activation by c-myc , 1993, Molecular and cellular biology.

[161]  V. Rotter,et al.  c-Myc trans-activates the p53 promoter through a required downstream CACGTG motif. , 1993, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[162]  Hisato Kondoh,et al.  Transition of localization of the N-Myc protein from nucleus to cytoplasm in differentiating neurons , 1993, Neuron.

[163]  R. Eisenman,et al.  Mad: A heterodimeric partner for Max that antagonizes Myc transcriptional activity , 1993, Cell.

[164]  Bruno Amati,et al.  Oncogenic activity of the c-Myc protein requires dimerization with Max , 1993, Cell.

[165]  R. Brent,et al.  Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites , 1993, Cell.

[166]  L. J. Veer,et al.  N‐myc suppresses major histocompatibility complex class I gene expression through down‐regulation of the p50 subunit of NF‐kappa B. , 1993, The EMBO journal.

[167]  N. Hay,et al.  Sequence-specific transcriptional activation by Myc and repression by Max , 1993, Molecular and cellular biology.

[168]  K. Struhl,et al.  The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted α Helices: Crystal structure of the protein-DNA complex , 1992, Cell.

[169]  V. Stewart,et al.  Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene. , 1992, Genes & development.

[170]  R. Shigemoto,et al.  Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split. , 1992, Genes & development.

[171]  G. Prendergast,et al.  Biphasic effect of Max on Myc cotransformation activity and dependence on amino- and carboxy-terminal Max functions. , 1992, Genes & development.

[172]  A. Perkins,et al.  Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop. , 1992, Genes & development.

[173]  P. Leder,et al.  An embryonically expressed gene is a target for c-Myc regulation via the c-Myc-binding sequence. , 1992, Genes & development.

[174]  L. Andersson,et al.  Ornithine decarboxylase activity is critical for cell transformation , 1992, Nature.

[175]  Wen-Hwa Lee,et al.  Abrogation by c-myc of Gl phase arrest induced by RB protein but not by p53 , 1992, Nature.

[176]  C. Gregory,et al.  Prevention of programmed cell death in burkitt lymphoma cell lines by bcl‐2‐dependent and ‐independent mechanisms , 1992, International journal of cancer.

[177]  D. Green,et al.  Apoptotic cell death induced by c-myc is inhibited by bcl-2 , 1992, Nature.

[178]  G. Evan,et al.  Cooperative interaction between c-myc and bcl-2 proto-oncogenes , 1992, Nature.

[179]  M. Jäättelä,et al.  Major heat shock protein hsp70 protects tumor cells from tumor necrosis factor cytotoxicity. , 1992, The EMBO journal.

[180]  C. Walker,et al.  First non-vertebrate member of the myc gene family is seasonally expressed in an invertebrate testis. , 1992, Oncogene.

[181]  R. Eisenman,et al.  Myc and Max proteins possess distinct transcriptional activities , 1992, Nature.

[182]  G. Evan,et al.  Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max , 1992, Nature.

[183]  C. Sawyers,et al.  Dominant negative MYC blocks transformation by ABL oncogenes , 1992, Cell.

[184]  Bert Vogelstein,et al.  p53 function and dysfunction , 1992, Cell.

[185]  S. Korsmeyer,et al.  The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[186]  R. Eisenman,et al.  Mitosis-specific phosphorylation of the nuclear oncoproteins Myc and Myb , 1992, The Journal of cell biology.

[187]  E. Taparowsky,et al.  v-Myc, but not Max, possesses domains that function in both transcription activation and cellular transformation. , 1992, Oncogene.

[188]  R. DePinho,et al.  Myc family oncoproteins function through a common pathway to transform normal cells in culture: cross-interference by Max and trans-acting dominant mutants. , 1992, Genes & development.

[189]  R. Mertelsmann,et al.  Expression of bcl-2 in Burkitt's lymphoma cell lines: induction by latent Epstein-Barr virus genes. , 1992, Blood.

[190]  D. Green,et al.  Role for c-myc in activation-induced apoptotic cell death in T cell hybridomas. , 1992, Science.

[191]  D. Lane,et al.  ras-Induced hyperplasia occurs with mutation of p53, but activated ras and myc together can induce carcinoma without p53 mutation , 1992, Cell.

[192]  E. Knust,et al.  Enhancer of splitD, a dominant mutation of Drosophila, and its use in the study of functional domains of a helix-loop-helix protein. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[193]  C. Dang,et al.  Activation domains of L-Myc and c-Myc determine their transforming potencies in rat embryo cells , 1992, Molecular and cellular biology.

[194]  G. D. Spotts,et al.  Translational activation of the non-AUG-initiated c-myc 1 protein at high cell densities due to methionine deprivation. , 1992, Genes & development.

[195]  V. Dixit,et al.  The A20 zinc finger protein protects cells from tumor necrosis factor cytotoxicity. , 1992, The Journal of biological chemistry.

[196]  C. Disteche,et al.  Mapping of MAX to human chromosome 14 and mouse chromosome 12 by in situ hybridization. , 1992, Oncogene.

[197]  Y. Shaul,et al.  c-abl has a sequence-specific enhancer binding activity , 1992, Cell.

[198]  A. Joyner,et al.  A targeted mutation reveals a role for N-myc in branching morphogenesis in the embryonic mouse lung. , 1992, Genes & development.

[199]  K. Alitalo,et al.  Alternative Forms of Max as Enhancers or Suppressors of Myc-Ras Cotransformation , 1992, Science.

[200]  S. Freytag,et al.  Reciprocal Regulation of Adipogenesis by Myc and C/EBPα , 1992, Science.

[201]  Gerard I. Evan,et al.  Induction of apoptosis in fibroblasts by c-myc protein , 1992, Cell.

[202]  M. L. Le Beau,et al.  Expression, regulation, and chromosomal localization of the Max gene. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[203]  N. Copeland,et al.  Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis , 1992, Nature.

[204]  L. Donehower,et al.  Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours , 1992, Nature.

[205]  D. Ron,et al.  CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription. , 1992, Genes & development.

[206]  M. Cole,et al.  Casein kinase II inhibits the DNA-binding activity of Max homodimers but not Myc/Max heterodimers. , 1992, Genes & development.

[207]  R. Davis,et al.  A phosphorylation site located in the NH2-terminal domain of c-Myc increases transactivation of gene expression. , 1991, The Journal of biological chemistry.

[208]  M. Schwab,et al.  The N‐Myc oncoprotein is associated in vivo with the phosphoprotein Max(p20/22) in human neuroblastoma cells. , 1991, The EMBO journal.

[209]  C. Baglioni,et al.  Protection from tumor necrosis factor-mediated cytolysis by overexpression of plasminogen activator inhibitor type-2. , 1991, The Journal of biological chemistry.

[210]  R. Ralston.  Complementation of transforming domains in E1a/myc chimaeras , 1991, Nature.

[211]  P. S. Kim,et al.  X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil. , 1991, Science.

[212]  A. Berk,et al.  Adenovirus E1A activation domain binds the basic repeat in the TATA box transcription factor , 1991, Cell.

[213]  Michael R. Green,et al.  Binding of general transcription factor TFIIB to an acidic activating region , 1991, Nature.

[214]  J. Cleveland,et al.  Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis. , 1991, Oncogene.

[215]  D. Vaux,et al.  Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[216]  T. Crook,et al.  p53 is frequently mutated in Burkitt's lymphoma cell lines. , 1991, The EMBO journal.

[217]  S. Shurtleff,et al.  Myc rescue of a mutant CSF-1 receptor impaired in mitogenic signalling , 1991, Nature.

[218]  K. Magnússon,et al.  Mutant p53 detected in a majority of Burkitt lymphoma cell lines by monoclonal antibody PAb240. , 1991, Oncogene.

[219]  T. Curran,et al.  Pro-Leu-Ser/Thr-Pro is a consensus primary sequence for substrate protein phosphorylation. Characterization of the phosphorylation of c-myc and c-jun proteins by an epidermal growth factor receptor threonine 669 protein kinase. , 1991, The Journal of biological chemistry.

[220]  A. Rustgi,et al.  Amino-terminal domains of c-myc and N-myc proteins mediate binding to the retinoblastoma gene product , 1991, Nature.

[221]  T. Halazonetis,et al.  Determination of the c-MYC DNA-binding site. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[222]  W. Fiers.  Tumor necrosis factor Characterization at the molecular, cellular and in vivo level , 1991, FEBS letters.

[223]  L. Larsson,et al.  Interferon gamma abrogates the differentiation block in v-myc-expressing U-937 monoblasts. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[224]  C. Goding,et al.  C-myc and the yeast transcription factor PHO4 share a common CACGTG-binding motif. , 1991, Oncogene.

[225]  R. Bronson,et al.  Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene , 1991, Cell.

[226]  E. Kieff,et al.  Induction of bcl-2 expression by epstein-barr virus latent membrane protein 1 protects infected B cells from programmed cell death , 1991, Cell.

[227]  S. Goff,et al.  Mice homozygous for the abl m1 mutation show poor viability and depletion of selected B and T cell populations , 1991, Cell.

[228]  G. Gaidano,et al.  p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[229]  T. Kadesch,et al.  The leucine zipper of TFE3 dictates helix-loop-helix dimerization specificity. , 1991, Genes & development.

[230]  Anton Berns,et al.  Identification of cooperating oncogenes in Eμ-myc transgenic mice by provirus tagging , 1991, Cell.

[231]  W. Alexander,et al.  Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in Eμ-myc transgenic mice , 1991, Cell.

[232]  V. Rotter,et al.  Expression from the murine p53 promoter is mediated by factor binding to a downstream helix-loop-helix recognition motif. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[233]  K. Klempnauer,et al.  Sequence-specific DNA binding by Myc proteins. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[234]  G. Prendergast,et al.  Association of Myn, the murine homolog of Max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation , 1991, Cell.

[235]  H. Hibshoosh,et al.  Effects of overexpression of ornithine decarboxylase (ODC) on growth control and oncogene-induced cell transformation. , 1991, Oncogene.

[236]  J. Moore,et al.  c-myc protein expression in untransformed fibroblasts. , 1991, Oncogene.

[237]  B. Wold,et al.  c-myc inhibition of MyoD and myogenin-initiated myogenic differentiation , 1991, Molecular and cellular biology.

[238]  B. de Crombrugghe,et al.  Transcriptional suppression of cellular gene expression by c-Myc , 1991, Molecular and cellular biology.

[239]  A. Berns,et al.  The pim‐1 oncogene encodes two related protein‐serine/threonine kinases by alternative initiation at AUG and CUG. , 1991, The EMBO journal.

[240]  S. L. Berger,et al.  Nuclear targeting of prothymosin alpha. , 1991, The Journal of biological chemistry.

[241]  Gwyn T. Williams,et al.  Activation of Epstein–Barr virus latent genes protects human B cells from death by apoptosis , 1991, Nature.

[242]  W. Schulz,et al.  A comparative analysis of N-myc and c-myc expression and cellular proliferation in mouse organogenesis , 1991, Mechanisms of Development.

[243]  A. Berns,et al.  Mice bearing the E mu-myc and E mu-pim-1 transgenes develop pre-B-cell leukemia prenatally , 1991, Molecular and cellular biology.

[244]  X. Bustelo,et al.  Expression of the rat prothymosin alpha gene during T-lymphocyte proliferation and liver regeneration. , 1991, The Journal of biological chemistry.

[245]  T. McDonnell,et al.  Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18) , 1991, Nature.

[246]  G. Prendergast,et al.  Methylation-sensitive sequence-specific DNA binding by the c-Myc basic region. , 1991, Science.

[247]  W. D. Cress,et al.  Critical structural elements of the VP16 transcriptional activation domain. , 1991, Science.

[248]  J. Bishop,et al.  The MYC protein activates transcription of the alpha‐prothymosin gene. , 1991, The EMBO journal.

[249]  A. Berns,et al.  Consecutive inactivation of both alleles of the pim-1 proto-oncogene by homologous recombination in embryonic stem cells , 1990, Nature.

[250]  G. Inghirami,et al.  Negative autoregulation of c‐myc gene expression is inactivated in transformed cells. , 1990, The EMBO journal.

[251]  K. Alitalo,et al.  Expression of the myc proto-oncogenes in developing human fetal brain. , 1990, Oncogene.

[252]  H. Wang,et al.  In vitro regulation of a SIN3-dependent DNA-binding activity by stimulatory and inhibitory factors. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[253]  H. Weintraub,et al.  Sequence-specific DNA binding by the c-Myc protein. , 1990, Science.

[254]  A. Strasser,et al.  Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2 , 1990, Nature.

[255]  G. Inghirami,et al.  Down-regulation of LFA-1 adhesion receptors by C-myc oncogene in human B lymphoblastoid cells. , 1990, Science.

[256]  J. Barrett,et al.  An amino-terminal c-myc domain required for neoplastic transformation activates transcription , 1990, Molecular and cellular biology.

[257]  J. Larrick,et al.  Cytotoxic mechanism of tumor necrosis factor‐α , 1990, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[258]  I. Weissman,et al.  IgH enhancer deregulated expression of L‐myc: abnormal T lymphocyte development and T cell lymphomagenesis. , 1990, The EMBO journal.

[259]  E. Prochownik,et al.  The leucine zipper of c-Myc is required for full inhibition of erythroleukemia differentiation , 1990, Molecular and cellular biology.

[260]  D. Morris,et al.  Cell type-specific mechanisms of regulating expression of the ornithine decarboxylase gene after growth stimulation , 1990, Molecular and cellular biology.

[261]  R. Roeder,et al.  The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer. , 1990, Genes & development.

[262]  R. Tjian,et al.  Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity. , 1990, Genes & development.

[263]  G. Evan,et al.  Domains of human c-myc protein required for autosuppression and cooperation with ras oncogenes are overlapping , 1990, Molecular and cellular biology.

[264]  J. Downing,et al.  A point mutation at tyrosine-809 in the human colony-stimulating factor 1 receptor impairs mitogenesis without abrogating tyrosine kinase activity, association with phosphatidylinositol 3-kinase, or induction of c-fos and junB genes. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[265]  E. Olson.  MyoD family: a paradigm for development? , 1990, Genes & development.

[266]  C. Croce,et al.  Complementation by BCL2 and C-HA-RAS oncogenes in malignant transformation of rat embryo fibroblasts , 1990, Molecular and cellular biology.

[267]  P. Sharp,et al.  A helix-loop-helix protein related to the immunoglobulin E box-binding proteins , 1990, Molecular and cellular biology.

[268]  C. Dang,et al.  Definition of the activities and properties of c-myc required to inhibit cell differentiation. , 1990, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[269]  C. Ingles,et al.  Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIID , 1990, Nature.

[270]  A. Berk,et al.  In vitro transcriptional activation, dimerization, and DNA-binding specificity of the Epstein-Barr virus Zta protein , 1990, Journal of virology.

[271]  R. Akeson,et al.  N-myc down regulates neural cell adhesion molecule expression in rat neuroblastoma , 1990, Molecular and cellular biology.

[272]  S. Korsmeyer,et al.  Deregulated Bcl-2-immunoglobulin transgene expands a resting but responsive immunoglobulin M and D-expressing B-cell population , 1990, Molecular and cellular biology.

[273]  D. Gillespie,et al.  The leucine zipper domain of avian cMyc is required for transformation and autoregulation. , 1990, Oncogene.

[274]  M. Erdos,et al.  Cellular levels of thymosin immunoreactive peptides are linked to proliferative events: evidence for a nuclear site of action. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[275]  J. Posakony,et al.  extramacrochaetae, a negative regulator of sensory organ development in Drosophila, defines a new class of helix-loop-helix proteins , 1990, Cell.

[276]  Harold Weintraub,et al.  The protein Id: A negative regulator of helix-loop-helix DNA binding proteins , 1990, Cell.

[277]  J. Modolell,et al.  The Drosophila extramacrochaetae locus, an antagonist of proneural genes that, like these genes, encodes a helix-loop-helix protein , 1990, Cell.

[278]  L. Penn,et al.  Negative autoregulation of c‐myc transcription. , 1990, The EMBO journal.

[279]  L. Persson,et al.  Molecular genetics of polyamine synthesis in eukaryotic cells. , 1990, Trends in biochemical sciences.

[280]  M. Cole,et al.  The c-myc-regulated gene mrl encodes plasminogen activator inhibitor 1 , 1990, Molecular and cellular biology.

[281]  J.M. Adams,et al.  An E mu‐v‐abl transgene elicits plasmacytomas in concert with an activated myc gene. , 1990, The EMBO journal.

[282]  L. Su,et al.  TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif. , 1990, Genes & development.

[283]  S. Y. Lee,et al.  Isolation and characterization of s-myc, a member of the rat myc gene family. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[284]  T. Soussi,et al.  Translocation of a store of maternal cytoplasmic c-myc protein into nuclei during early development , 1989, Molecular and cellular biology.

[285]  K. Grabstein,et al.  Stage-specific transformation of murine B lineage cells by ras and myc. , 1989, Oncogene.

[286]  R. Eisenman,et al.  FH3, a v-myc avian retrovirus with limited transforming ability , 1989, Journal of virology.

[287]  G. Wong,et al.  Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor , 1989, Cell.

[288]  R. Tjian,et al.  Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. , 1989, Science.

[289]  Didier Picard,et al.  Chimaeras of Myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells , 1989, Nature.

[290]  J. Bishop,et al.  Contrasting patterns of myc and N-myc expression during gastrulation of the mouse embryo. , 1989, Genes & development.

[291]  J. Karn,et al.  Regulation of cell cycle duration by c-myc levels. , 1989, Oncogene.

[292]  J. Calvet,et al.  Sequential protooncogene expression in regenerating kidney following acute renal injury. , 1989, The Journal of biological chemistry.

[293]  W. Alexander,et al.  Lymphomagenesis in E mu-myc transgenic mice can involve ras mutations. , 1989, Oncogene.

[294]  S. Korsmeyer,et al.  bcl-2-Immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation , 1989, Cell.

[295]  S. Ma,et al.  Tissue and age specific expression of the myc proto-oncogene family throughout the life span of the C57BL/6J mouse strain. , 1989, Oncogene.

[296]  E. Krebs,et al.  Myc oncoproteins are phosphorylated by casein kinase II. , 1989, The EMBO journal.

[297]  F. Alt,et al.  IgH enhancer‐mediated deregulation of N‐myc gene expression in transgenic mice: generation of lymphoid neoplasias that lack c‐myc expression. , 1989, The EMBO journal.

[298]  David Baltimore,et al.  A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins , 1989, Cell.

[299]  A. W. Harris,et al.  N‐myc transgene promotes B lymphoid proliferation, elicits lymphomas and reveals cross‐regulation with c‐myc. , 1989, The EMBO journal.

[300]  O. Witte,et al.  The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc , 1989, Molecular and cellular biology.

[301]  A. Berns,et al.  Predisposition to lymphomagenesis in pim-1 transgenic mice: Cooperation with c-myc and N-myc in murine leukemia virus-induced tumors , 1989, Cell.

[302]  W. Schulz,et al.  Dynamic expression pattern of the myc protooncogene in midgestation mouse embryos. , 1989, Science.

[303]  C. Klämbt,et al.  Closely related transcripts encoded by the neurogenic gene complex enhancer of split of Drosophila melanogaster. , 1989, The EMBO journal.

[304]  M. Cole,et al.  Posttranscriptional regulation of cellular gene expression by the c-myc oncogene , 1989, Molecular and cellular biology.

[305]  W. Alexander,et al.  Oncogene cooperation in lymphocyte transformation: malignant conversion of E mu-myc transgenic pre-B cells in vitro is enhanced by v-H-ras or v-raf but not v-abl , 1989, Molecular and cellular biology.

[306]  A. Lavenu,et al.  c-myc products trans-activate the adenovirus E4 promoter in EC stem cells by using the same target sequence as E1A products , 1988, Journal of virology.

[307]  P. Leder,et al.  A human immunoglobulin gene reduces the incidence of lymphomas in c-Myc-bearing transgenic mice , 1988, Nature.

[308]  M. McBurney,et al.  Two transient increases in c-myc gene expression during neuroectodermal differentiation of mouse embryonal carcinoma cells. , 1988, Oncogene.

[309]  J U Gutterman,et al.  The molecular genetics of Philadelphia chromosome-positive leukemias. , 1988, The New England journal of medicine.

[310]  C. Dang,et al.  Identification of the human c-myc protein nuclear translocation signal , 1988, Molecular and cellular biology.

[311]  F. Alt,et al.  N-myc proto-oncogene expression during organogenesis in the developing mouse as revealed by in situ hybridization , 1988, The Journal of cell biology.

[312]  David L. Vaux,et al.  Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells , 1988, Nature.

[313]  H. Westphal,et al.  Antisense Myc sequences induce differentiation of F9 cells. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[314]  E. Prochownik,et al.  c-myc antisense transcripts accelerate differentiation and inhibit G1 progression in murine erythroleukemia cells , 1988, Molecular and cellular biology.

[315]  G. Klein,et al.  Structure and expression of B-myc, a new member of the myc gene family , 1988, Molecular and cellular biology.

[316]  S. McKnight,et al.  The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins. , 1988, Science.

[317]  E. Sausville,et al.  L-myc cooperates with ras to transform primary rat embryo fibroblasts , 1988, Molecular and cellular biology.

[318]  S. Freytag.  Enforced expression of the c-myc oncogene inhibits cell differentiation by precluding entry into a distinct predifferentiation state in G0/G1 , 1988, Molecular and cellular biology.

[319]  R. Versteeg,et al.  c‐myc down‐regulates class I HLA expression in human melanomas. , 1988, The EMBO journal.

[320]  U. Pettersson,et al.  Phorbol ester-induced terminal differentiation is inhibited in human U-937 monoblastic cells expressing a v-myc oncogene. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[321]  A. Nienhuis,et al.  An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyelocytic cells and induces differentiation , 1988, Molecular and cellular biology.

[322]  A. W. Harris,et al.  The E mu-myc transgenic mouse. A model for high-incidence spontaneous lymphoma and leukemia of early B cells , 1988, The Journal of experimental medicine.

[323]  R. Eisenman,et al.  A non-AUG translational initiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is disrupted in Burkitt's lymphomas , 1988, Cell.

[324]  D. Spandidos,et al.  Rodent fibroblast tumours expressing human myc and ras genes: growth, metastasis and endogenous oncogene expression. , 1987, British Journal of Cancer.

[325]  K. Hayashi,et al.  Nucleic Acids Research Characterization of Rat C-myc and Adjacent Regions , 2022 .

[326]  J. Greene,et al.  Activation and repression of mammalian gene expression by the c-myc protein. , 1987, Genes & development.

[327]  P. Leder,et al.  Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: Synergistic action of oncogenes in vivo , 1987, Cell.

[328]  H. Varmus,et al.  Definition of regions in human c-myc that are involved in transformation and nuclear localization , 1987, Molecular and cellular biology.

[329]  D. Beer,et al.  Specific gene expression during compensatory renal hypertrophy in the rat , 1987, Journal of cellular physiology.

[330]  C. Croce,et al.  DNA rearrangements in human follicular lymphoma can involve the 5' or the 3' region of the bcl-2 gene. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[331]  R. Getzenberg,et al.  c-myc mRNA is elevated as differentiating lens cells withdraw from the cell cycle. , 1987, Experimental cell research.

[332]  M. Oken,et al.  Multiple recurrent genomic defects in follicular lymphoma. A possible model for cancer. , 1987, The New England journal of medicine.

[333]  R. Weinberg,et al.  N-myc amplification causes down-modulation of MHC class I antigen expression in neuroblastoma , 1986, Cell.

[334]  R. Eisenman,et al.  Expression of the c-myc proto-oncogene during development of Xenopus laevis , 1986, Molecular and cellular biology.

[335]  M. Méchali,et al.  Xenopus myc proto‐oncogene during development: expression as a stable maternal mRNA uncoupled from cell division. , 1986, The EMBO journal.

[336]  V. Sorrentino,et al.  Potentiation of growth factor activity by exogenous c-myc expression. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[337]  R. Weinberg,et al.  c‐myc and c‐fos expression in differentiating mouse primary keratinocytes. , 1986, The EMBO journal.

[338]  A. W. Harris,et al.  The c-myc oncogene perturbs B lymphocyte development in Eμ-myc transgenic mice , 1986, Cell.

[339]  J. Sklar,et al.  Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation , 1986, Cell.

[340]  L. Stanton,et al.  Synergism of v-myc and v-Ha-ras in the in vitro neoplastic progression of murine lymphoid cells , 1986, Molecular and cellular biology.

[341]  E. Dmitrovsky,et al.  Expression of a transfected human c-myconcogene inhibits differentiation of a mouse erythroleukaemia cell line , 1986, Nature.

[342]  H. DeLuca,et al.  Decreased c-myc expression is an early event in retinoic acid-induced differentiation of F9 teratocarcinoma cells. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[343]  R. Kingston,et al.  Inducible overproduction of the mouse c-myc protein in mammalian cells. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[344]  J. Lautenberger,et al.  Cellular myc (c-myc) in fish (rainbow trout): its relationship to other vertebrate myc genes and to the transforming genes of the MC29 family of viruses. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[345]  N. Thompson,et al.  Sequential protooncogene expression during rat liver regeneration. , 1986, Cancer research.

[346]  M. Cole,et al.  Constitutive c-myc oncogene expression blocks mouse erythroleukaemia cell differentiation but not commitment , 1986, Nature.

[347]  P. Sunkara,et al.  Ornithine decarboxylase induction and polyamine biosynthesis are required for the growth of interleukin-2- and interleukin-3-dependent cell lines. , 1986, Cellular immunology.

[348]  M. Sporn,et al.  Differential responsiveness of myc- and ras-transfected cells to growth factors: selective stimulation of myc-transfected cells by epidermal growth factor , 1986, Molecular and cellular biology.

[349]  W. Richardson,et al.  Nuclear location signals in polyoma virus large-T , 1986, Cell.

[350]  R. Palmiter,et al.  The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice , 1985, Nature.

[351]  P. Ingham,et al.  Transcription pattern of the Drosophila segmentation gene hairy , 1985, Nature.

[352]  M. Schwab,et al.  Expression of N-myc in teratocarcinoma stem cells and mouse embryos , 1985, Nature.

[353]  J. Battey,et al.  L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer , 1985, Nature.

[354]  C. Croce,et al.  The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining. , 1985, Science.

[355]  C. Betsholtz,et al.  Cell-type-specific pattern of myc protooncogene expression in developing human embryos. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[356]  G. Evan,et al.  Metabolism of c‐myc gene products: c‐myc mRNA and protein expression in the cell cycle. , 1985, EMBO Journal.

[357]  S. Korsmeyer,et al.  Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around Jh on chromosome 14 and near a transcriptional unit on 18 , 1985, Cell.

[358]  A. Berns,et al.  Proviral activation of the putative oncogene Pim‐1 in MuLV induced T‐cell lymphomas. , 1985, The EMBO journal.

[359]  R. Eisenman,et al.  c-myc oncogene protein synthesis is independent of the cell cycle in human and avian cells , 1985, Nature.

[360]  J. Trent,et al.  Chromosome localization in normal human cells and neuroblastomas of a gene related to c-myc , 1984, Nature.

[361]  P. Sharp,et al.  Regulation of heat shock protein 70 gene expression by c-myc , 1984, Nature.

[362]  Michael E. Greenberg,et al.  Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene , 1984, Nature.

[363]  P. Leder,et al.  Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes , 1984, Cell.

[364]  W. Richardson,et al.  Sequence requirements for nuclear location of simian virus 40 large-T antigen , 1984, Nature.

[365]  R. Ohlsson,et al.  Spatial and temporal pattern of cellular myc oncogene expression in developing human placenta: Implications for embryonic cell proliferation , 1984, Cell.

[366]  P. Leder,et al.  Functional role for c-myc in mitogenic response to platelet-derived growth factor , 1984, Nature.

[367]  H. Lachman,et al.  Expression of c-myc changes during differentiation of mouse erythroleukaemia cells , 1984, Nature.

[368]  L. Stanton,et al.  Nucleotide sequence comparison of normal and translocated murine c-myc genes , 1984, Nature.

[369]  Wim Quint,et al.  Murine leukemia virus-induced T-cell lymphomagenesis: Integration of proviruses in a distinct chromosomal region , 1984, Cell.

[370]  H. E. Gray,et al.  Cell-cycle control of c-myc but not c-ras expression is lost following chemical transformation , 1984, Cell.

[371]  F. Alt,et al.  Transposition and amplification of oncogene-related sequences in human neuroblastomas , 1983, Cell.

[372]  J. Trent,et al.  Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour , 1983, Nature.

[373]  P. Leder,et al.  Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor , 1983, Cell.

[374]  T. Graf,et al.  Quail embryo fibroblasts transformed by four v‐myc‐containing virus isolates show enhanced proliferation but are non tumorigenic. , 1983, The EMBO journal.

[375]  P. Reitsma,et al.  Regulation of myc gene expression in HL-60 leukaemia cells by a vitamin D metabolite , 1983, Nature.

[376]  H. Ruley.  Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture , 1983, Nature.

[377]  Robert A. Weinberg,et al.  Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes , 1983, Nature.

[378]  L. Hood,et al.  Mouse c-myc oncogene is located on chromosome 15 and translocated to chromosome 12 in plasmacytomas. , 1982, Science.

[379]  C. Croce,et al.  Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[380]  J. Bishop,et al.  Transcripts from the Cellular Homologs of Retroviral Oncogenes: Distribution Among Chicken Tissues , 1982, Molecular and cellular biology.

[381]  B. Vennstrom,et al.  Isolation and characterization of c-myc, a cellular homolog of the oncogene (v-myc) of avian myelocytomatosis virus strain 29 , 1982, Journal of virology.

[382]  D. Baltimore,et al.  Structure of the Abelson murine leukemia virus genome and the homologous cellular gene: Studies with cloned viral DNA , 1980, Cell.

[383]  J. Bishop,et al.  DNA and RNA from Uninfected Vertebrate Cells Contain Nucleotide Sequences Related to the Putative Transforming Gene of Avian Myelocytomatosis Virus , 1979, Journal of virology.

[384]  T. Graf,et al.  Avian leukemia viruses: interaction with their target cells in vivo and in vitro. , 1978, Biochimica et biophysica acta.

[385]  J. Bishop,et al.  Identification of nucleotide sequences which may encode the oncogenic capacity of avian retrovirus MC29 , 1978, Journal of virology.

[386]  K. Wiman,et al.  p53: a cell cycle regulator activated by DNA damage. , 1995, Advances in cancer research.

[387]  A. Ferré-D’Amaré,et al.  Structure and function of the b/HLH/Z domain of USF , 1994 .

[388]  J. Woodgett,et al.  Site-specific modulation of c-Myc cotransformation by residues phosphorylated in vivo. , 1994, Oncogene.

[389]  P. Krieg,et al.  Analysis of a variant Max sequence expressed in Xenopus laevis. , 1994, Oncogene.

[390]  G. Gaidano,et al.  Mutations in the coding region of c-myc occur frequently in acquired immunodeficiency syndrome-associated lymphomas. , 1994, Blood.

[391]  K. Calame,et al.  An analysis of genes regulated by the multi-functional transcriptional regulator Yin Yang-1. , 1994, Nucleic acids research.

[392]  J. Šmarda,et al.  c-Myb prevents TPA-induced differentiation and cell death in v-Myb transformed monoblasts. , 1994, Oncogene.

[393]  F. C. Lucibello,et al.  Oncogenic activity of cyclin D1 revealed through cooperation with Ha-ras: link between cell cycle control and malignant transformation. , 1994, Oncogene.

[394]  T. Halazonetis,et al.  Both the helix-loop-helix and the leucine zipper motifs of c-Myc contribute to its dimerization specificity with Max. , 1993, Oncogene.

[395]  A. Baxevanis,et al.  Interactions of coiled coils in transcription factors: where is the specificity? , 1993, Current opinion in genetics & development.

[396]  M. Mori,et al.  Prothymosin-α mRNA expression correlates with that of c-myc in human colon cancer , 1993 .

[397]  A. Strasser,et al.  E mu-bcl-2 transgene facilitates spontaneous transformation of early pre-B and immunoglobulin-secreting cells but not T cells. , 1993, Oncogene.

[398]  L. Álvarez-Fernández,et al.  Differentiation-Linked Expression of Prothymosin α Gene in Human Myeloid Leukemic Cells , 1993 .

[399]  S. Korsmeyer,et al.  Collaboration of pim-1 and bcl-2 in lymphomagenesis. , 1992, Current topics in microbiology and immunology.

[400]  M. Cole,et al.  max encodes a sequence-specific DNA-binding protein and is not regulated by serum growth factors. , 1992, Oncogene.

[401]  R. Eisenman,et al.  Myc and Max associate in vivo. , 1992, Genes & development.

[402]  C. Dang,et al.  Max: functional domains and interaction with c-Myc. , 1992, Genes & development.

[403]  A. Patel,et al.  myc function and regulation. , 1992, Annual review of biochemistry.

[404]  T. Alber.  Structure of the leucine zipper. , 1992 .

[405]  M. Groudine,et al.  Control of c-myc regulation in normal and neoplastic cells. , 1991, Advances in cancer research.

[406]  S. L. Berger,et al.  Prothymosin alpha antisense oligomers inhibit myeloma cell division. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[407]  F. Alt,et al.  myc family oncogenes in the development of normal and neoplastic cells. , 1991, Advances in cancer research.

[408]  D. Vaux,et al.  Abnormalities of the immune system induced by dysregulated bcl-2 expression in transgenic mice. , 1990, Current topics in microbiology and immunology.

[409]  R. Eisenman,et al.  Mutational analysis of the carboxy-terminal casein kinase II phosphorylation site in human c-myc. , 1990, Current topics in microbiology and immunology.

[410]  D. Spandidos,et al.  The role of ras and myc oncogenes in human solid tumours and their relevance in diagnosis and prognosis (review). , 1990, Anticancer research.

[411]  C. Asselin,et al.  Mode of c-myc gene regulation in folic acid-induced kidney regeneration. , 1989, Oncogene research.

[412]  A. W. Harris,et al.  Acceleration of B-lymphoid tumorigenesis in E mu-myc transgenic mice by v-H-ras and v-raf but not v-abl. , 1989, Oncogene research.

[413]  F. Alt,et al.  Chromosomal location of N-myc and L-myc genes in the mouse. , 1989, Oncogene research.

[414]  C. Babinet,et al.  Exogenous c-myc gene overexpression interferes with early events in F9 cell differentiation. , 1989, Oncogene research.

[415]  N. Rosenberg,et al.  The viral and cellular forms of the Abelson (abl) oncogene. , 1988, Advances in virus research.

[416]  P. Leder,et al.  Evolutionarily conserved regions of the human c-myc protein can be uncoupled from transforming activity. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[417]  Eric Wickstrom,et al.  A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1 , 1987, Nature.

[418]  H. Ruley,et al.  Role of c-myc in the transformation of REF52 cells by viral and cellular oncogenes. , 1987, Oncogene.

[419]  H. Jansen,et al.  Oncogenes in retroviruses and cells: biochemistry and molecular genetics. , 1986, Advances in cancer research.

[420]  F. Alt,et al.  Differential expression of myc family genes during murine development , 1986, Nature.

[421]  A. Wyllie.  The biology of cell death in tumours. , 1985, Anticancer research.

[422]  M. Groudine,et al.  Levels of c-myc oncogene mRNA are invariant throughout the cell cycle , 1985, Nature.

[423]  J. Bishop,et al.  The protein products of the myc and myb oncogenes and adenovirus E1a are structurally related , 1983, Nature.