Method for in situ characterization of radiofrequency heating in parallel transmit MRI

In ultra‐high‐field magnetic resonance imaging, parallel radiofrequency (RF) transmission presents both opportunities and challenges for specific absorption rate management. On one hand, parallel transmission provides flexibility in tailoring electric fields in the body while facilitating magnetization profile control. On the other hand, it increases the complexity of energy deposition as well as possibly exacerbating local specific absorption rate by improper design or delivery of RF pulses. This study shows that the information needed to characterize RF heating in parallel transmission is contained within a local power correlation matrix. Building upon a calibration scheme involving a finite number of magnetic resonance thermometry measurements, this work establishes a way of estimating the local power correlation matrix. Determination of this matrix allows prediction of temperature change for an arbitrary parallel transmit RF pulse. In the case of a three transmit coil MR experiment in a phantom, determination and validation of the power correlation matrix were conducted in less than 200 min with induced temperature changes of <4°C. Further optimization and adaptation are possible, and simulations evaluating potential feasibility for in vivo use are presented. The method allows general characteristics indicative of RF coil/pulse safety determined in situ. Magn Reson Med, 2013. © 2012 Wiley Periodicals, Inc.

[1]  Fritz Schick,et al.  Accuracy of real-time MR temperature mapping in the brain: a comparison of fast sequences. , 2010, Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics.

[2]  Lin Tang,et al.  Studies of RF Shimming Techniques with Minimization of RF Power Deposition and Their Associated Temperature Changes. , 2011, Concepts in magnetic resonance. Part B, Magnetic resonance engineering.

[3]  Olaf Dössel,et al.  Local SAR management by RF Shimming: a simulation study with multiple human body models , 2012, Magnetic Resonance Materials in Physics, Biology and Medicine.

[4]  H. Reinhold Physiological effects of hyperthermia. , 1988, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

[5]  Kim Butts Pauly,et al.  MR thermometry , 2008, Journal of magnetic resonance imaging : JMRI.

[6]  R. Mallozzi,et al.  Radiofrequency power deposition utilizing thermal imaging , 2004, Magnetic resonance in medicine.

[7]  C Gabriel,et al.  The dielectric properties of biological tissues: I. Literature survey. , 1996, Physics in medicine and biology.

[8]  Daniel K Sodickson,et al.  System and SAR characterization in parallel RF transmission , 2012, Magnetic resonance in medicine.

[9]  H. Bicher,et al.  Local hyperthermia for deep tumors. , 1990, Advances in experimental medicine and biology.

[10]  K. Kuroda,et al.  A precise and fast temperature mapping using water proton chemical shift , 1995, Magnetic resonance in medicine.

[11]  H. H. Pennes Analysis of tissue and arterial blood temperatures in the resting human forearm. , 1948, Journal of applied physiology.

[12]  Y. Zhu In Vivo RF Power and SAR Calibration for Multi-Port RF Transmission , 2008 .

[13]  K. Uğurbil,et al.  Temperature and SAR calculations for a human head within volume and surface coils at 64 and 300 MHz , 2004, Journal of magnetic resonance imaging : JMRI.

[14]  Whole Grain Label Statements Guidance for Industry and FDA Staff , 2006 .

[15]  D. Hoult Sensitivity and Power Deposition in a High‐Field Imaging Experiment , 2000, Journal of magnetic resonance imaging : JMRI.

[16]  Christopher M Collins,et al.  Numerical field calculations considering the human subject for engineering and safety assurance in MRI , 2009, NMR in biomedicine.

[17]  Daniel K Sodickson,et al.  Specific absorption rate benefits of including measured electric field interactions in parallel excitation pulse design , 2012, Magnetic resonance in medicine.

[18]  P. Börnert,et al.  Transmit SENSE , 2003, Magnetic resonance in medicine.

[19]  Yudong Zhu,et al.  Parallel excitation with an array of transmit coils , 2004, Magnetic resonance in medicine.