High-efficiency pharmacogenetic ablation of oligodendrocyte progenitor cells in the adult mouse CNS

[1]  K. Green,et al.  To Kill a Microglia: A Case for CSF1R Inhibitors. , 2020, Trends in immunology.

[2]  A. Ben-nun,et al.  The Median Eminence, A New Oligodendrogenic Niche in the Adult Mouse Brain , 2020, Stem cell reports.

[3]  A. Sierra,et al.  Microglial Corpse Clearance: Lessons From Macrophages , 2020, Frontiers in Immunology.

[4]  B. Hughes,et al.  The dynamics of oligodendrocyte generation: how distinct is the mouse from the human? , 2019, bioRxiv.

[5]  C. Betsholtz,et al.  Powerful Homeostatic Control of Oligodendroglial Lineage by PDGFRα in Adult Brain. , 2019, Cell reports.

[6]  H. Ding,et al.  BMP4 and Neuregulin regulate the direction of mouse neural crest cell differentiation , 2019, Experimental and therapeutic medicine.

[7]  S. Dietmann,et al.  Oligodendrocyte Progenitor Cells Become Regionally Diverse and Heterogeneous with Age , 2019, Neuron.

[8]  Koji Ando,et al.  A molecular atlas of cell types and zonation in the brain vasculature , 2018, Nature.

[9]  H. Yao,et al.  A new mouse line for cell ablation by diphtheria toxin subunit A controlled by a Cre‐dependent FLEx switch , 2017, Genesis.

[10]  Yasuyoshi Watanabe,et al.  NG2 glial cells regulate neuroimmunological responses to maintain neuronal function and survival , 2017, Scientific Reports.

[11]  P. Sorger,et al.  Cyclic Immunofluorescence (CycIF), A Highly Multiplexed Method for Single‐cell Imaging , 2016, Current protocols in chemical biology.

[12]  Hui Wang,et al.  NG2 expression in microglial cells affects the expression of neurotrophic and proinflammatory factors by regulating FAK phosphorylation , 2016, Scientific Reports.

[13]  Jens Hjerling-Leffler,et al.  Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system , 2016, Science.

[14]  M. Cayre,et al.  Region and dynamic specificities of adult neural stem cells and oligodendrocyte precursors in myelin regeneration in the mouse brain , 2016, Biology Open.

[15]  A. Maffei,et al.  Genetic and Stress-Induced Loss of NG2 Glia Triggers Emergence of Depressive-like Behaviors through Reduced Secretion of FGF2 , 2015, Neuron.

[16]  L. Iacovitti,et al.  Classic and novel stem cell niches in brain homeostasis and repair , 2015, Brain Research.

[17]  G. Fishell,et al.  Inhibition of Gli1 mobilizes endogenous neural stem cells for remyelination , 2015, Nature.

[18]  W. D. den Dunnen,et al.  Cell Junction Pathology of Neural Stem Cells Is Associated With Ventricular Zone Disruption, Hydrocephalus, and Abnormal Neurogenesis , 2015, Journal of neuropathology and experimental neurology.

[19]  M. Cayre,et al.  Region and dynamic specificities of adult neural stem cells and oligodendrocyte precursors in myelin regeneration in the mouse brain , 2015, Biology Open.

[20]  T. Kilpatrick,et al.  Adult Neural Precursor Cells from the Subventricular Zone Contribute Significantly to Oligodendrocyte Regeneration and Remyelination , 2014, The Journal of Neuroscience.

[21]  Kai-Florian Storch,et al.  Extensive regenerative plasticity among adult NG2‐glia populations is exclusively based on self‐renewal , 2013, Glia.

[22]  M. Fukaya,et al.  Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain , 2013, Nature Neuroscience.

[23]  D. Attwell,et al.  Oligodendrocyte Dynamics in the Healthy Adult CNS: Evidence for Myelin Remodeling , 2013, Neuron.

[24]  A. Roberts,et al.  Ablation of NG2 Proteoglycan Leads to Deficits in Brown Fat Function and to Adult Onset Obesity , 2012, PloS one.

[25]  Dwight E. Bergles,et al.  NG2+ CNS Glial Progenitors Remain Committed to the Oligodendrocyte Lineage in Postnatal Life and following Neurodegeneration , 2010, Neuron.

[26]  D. Rowitch,et al.  CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination. , 2010, Cell stem cell.

[27]  W. Macklin,et al.  Distinct modes of migration position oligodendrocyte precursors for localized cell division in the developing spinal cord , 2009, Journal of neuroscience research.

[28]  N. Kessaris,et al.  PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice , 2008, Nature Neuroscience.

[29]  D. Attwell,et al.  Spiking and nonspiking classes of oligodendrocyte precursor glia in CNS white matter , 2008, Nature Neuroscience.

[30]  D. Bergles,et al.  Vesicular release of glutamate from unmyelinated axons in white matter , 2007, Nature Neuroscience.

[31]  K. Irvine,et al.  A different regional response by mouse oligodendrocyte progenitor cells (OPCs) to high‐dose X‐irradiation has consequences for repopulating OPC‐depleted normal tissue , 2007, The European journal of neuroscience.

[32]  Oscar Gonzalez-Perez,et al.  Origin of Oligodendrocytes in the Subventricular Zone of the Adult Brain , 2006, The Journal of Neuroscience.

[33]  Ryoichiro Kageyama,et al.  Temporal regulation of Cre recombinase activity in neural stem cells , 2006, Genesis.

[34]  Palma Iannarelli,et al.  Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage , 2006, Nature Neuroscience.

[35]  V. Gallo,et al.  NG2‐positive cells in the mouse white and grey matter display distinct physiological properties , 2004, The Journal of physiology.

[36]  Y. Qi,et al.  Selective Expression of Nkx-2.2 Transcription Factor in Chicken Oligodendrocyte Progenitors and Implications for the Embryonic Origin of Oligodendrocytes , 2000, Molecular and Cellular Neuroscience.

[37]  Joanne Chan,et al.  Sonic Hedgehog–Regulated Oligodendrocyte Lineage Genes Encoding bHLH Proteins in the Mammalian Central Nervous System , 2000, Neuron.

[38]  J. García-Verdugo,et al.  Regeneration of a germinal layer in the adult mammalian brain. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[39]  Daniel A. Lim,et al.  Subventricular Zone Astrocytes Are Neural Stem Cells in the Adult Mammalian Brain , 1999, Cell.

[40]  R. Schmidt-Kastner,et al.  Nestin expression in reactive astrocytes following focal cerebral ischemia in rats , 1997, Brain Research.

[41]  R. McKay,et al.  Re-expression of the intermediate filament nestin in reactive astrocytes , 1995, Neurobiology of Disease.

[42]  C. Heldin,et al.  Expression of Platelet-Derived Growth Factor (PDGF) and PDGF α- and β-Receptors in the Peripheral Nervous System: An Analysis of Sciatic Nerve and Dorsal Root Ganglia , 1993 .

[43]  W. Richardson,et al.  PDGF receptors in the rat CNS: during late neurogenesis, PDGF alpha-receptor expression appears to be restricted to glial cells of the oligodendrocyte lineage. , 1992, Development.

[44]  A. van Koppen,et al.  Regulation and role of PDGF receptor alpha-subunit expression during embryogenesis. , 1992, Development.

[45]  W. D. den Dunnen,et al.  A cell junction pathology of neural stem cells leads to abnormal neurogenesis and hydrocephalus. , 2012, Biological research.

[46]  A. Nishiyama,et al.  Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity , 2009, Nature Reviews Neuroscience.

[47]  K. Nave,et al.  The transcription factor Sox10 is a key regulator of peripheral glial development. , 2001, Genes & development.