Neurorestorative Targets of Dietary Long-Chain Omega-3 Fatty Acids in Neurological Injury

[1]  M. León,et al.  Metabolomics uncovers dietary omega-3 fatty acid-derived metabolites implicated in anti-nociceptive responses after experimental spinal cord injury , 2013, Neuroscience.

[2]  M. Fehlings,et al.  Do omega-3 polyunsaturated fatty acids ameliorate spinal cord injury? Commentary on: Lim et al., Improved outcome after spinal cord compression injury in mice treated with docosahexaeonic acid. Exp. Neurol. Jan; 239:13–27 , 2013, Experimental Neurology.

[3]  T. Nakaki,et al.  Impaired Glutathione Synthesis in Neurodegeneration , 2013, International journal of molecular sciences.

[4]  P. Marignani,et al.  Omega-3 polyunsaturated fatty acid promotes the inhibition of glycolytic enzymes and mTOR signaling by regulating the tumor suppressor LKB1 , 2013, Cancer biology & therapy.

[5]  C. Hulsebosch,et al.  Reactive oxygen species contribute to neuropathic pain and locomotor dysfunction via activation of CamKII in remote segments following spinal cord contusion injury in rats , 2013, PAIN®.

[6]  M. De León,et al.  Dietary omega-3 polyunsaturated fatty acids improve the neurolipidome and restore the DHA status while promoting functional recovery after experimental spinal cord injury. , 2013, Journal of neurotrauma.

[7]  Bin Zhang,et al.  Temporospatial expression and cellular localization of glutamine synthetase following traumatic spinal cord injury in adult rats. , 2013, Molecular medicine reports.

[8]  Xue-chuan Shi,et al.  Mechanisms of Neuroprotection from Hypoxia-Ischemia (HI) Brain Injury by Up-regulation of Cytoglobin (CYGB) in a Neonatal Rat Model* , 2013, The Journal of Biological Chemistry.

[9]  T. Nakaki,et al.  Neuroprotective properties of the excitatory amino acid carrier 1 (EAAC1) , 2013, Amino Acids.

[10]  J. Priestley,et al.  Transgenic mice with high endogenous omega-3 fatty acids are protected from spinal cord injury , 2013, Neurobiology of Disease.

[11]  P. Pattany,et al.  Metabolite concentrations in the anterior cingulate cortex predict high neuropathic pain impact after spinal cord injury , 2013, PAIN.

[12]  J. Priestley,et al.  Improved outcome after spinal cord compression injury in mice treated with docosahexaenoic acid , 2013, Experimental Neurology.

[13]  David S. Wishart,et al.  HMDB 3.0—The Human Metabolome Database in 2013 , 2012, Nucleic Acids Res..

[14]  P. Klivényi,et al.  Mitochondrial disturbances, excitotoxicity, neuroinflammation and kynurenines: Novel therapeutic strategies for neurodegenerative disorders , 2012, Journal of the Neurological Sciences.

[15]  E. Fukusaki,et al.  Metabolite Profiles Correlate Closely with Neurobehavioral Function in Experimental Spinal Cord Injury in Rats , 2012, PloS one.

[16]  L. Holly,et al.  LABORATORY INVESTIGATION , 2005 .

[17]  A. Obenaus,et al.  Novel aspirin-triggered neuroprotectin D1 attenuates cerebral ischemic injury after experimental stroke , 2012, Experimental Neurology.

[18]  J. Priestley,et al.  Docosahexaenoic acid, but not eicosapentaenoic acid, reduces the early inflammatory response following compression spinal cord injury in the rat , 2012, Journal of neurochemistry.

[19]  M. Ohsawa,et al.  Carnosine has antinociceptive properties in the inflammation-induced nociceptive response in mice. , 2012, European journal of pharmacology.

[20]  David S. Wishart,et al.  MetaboAnalyst 2.0—a comprehensive server for metabolomic data analysis , 2012, Nucleic Acids Res..

[21]  P. Klivényi,et al.  Mitochondrial disturbances, tryptophan metabolites and neurodegeneration: medicinal chemistry aspects. , 2012, Current medicinal chemistry.

[22]  J. Miranda,et al.  Docosahexaenoic acid pretreatment confers protection and functional improvements after acute spinal cord injury in adult rats. , 2012, Journal of neurotrauma.

[23]  A. Sinclair,et al.  Effects of Zinc and DHA on the Epigenetic Regulation of Human Neuronal Cells , 2012, Cellular Physiology and Biochemistry.

[24]  M. Wahlqvist,et al.  Effect of n-3 polyunsaturated fatty acid on gene expression of the critical enzymes involved in homocysteine metabolism , 2012, Nutrition Journal.

[25]  A. Salinaro,et al.  Administration of carnosine in the treatment of acute spinal cord injury. , 2011, Biochemical pharmacology.

[26]  N. Bazan,et al.  Endogenous Signaling by Omega-3 Docosahexaenoic Acid-derived Mediators Sustains Homeostatic Synaptic and Circuitry Integrity , 2011, Molecular Neurobiology.

[27]  S. Cuzzocrea,et al.  Neuroprotective features of carnosine in oxidative driven diseases. , 2011, Molecular aspects of medicine.

[28]  M. Fehlings,et al.  A systematic review of non-invasive pharmacologic neuroprotective treatments for acute spinal cord injury. , 2011, Journal of neurotrauma.

[29]  E. Westman,et al.  1H-MRS in spinal cord injury: acute and chronic metabolite alterations in rat brain and lumbar spinal cord , 2011, The European journal of neuroscience.

[30]  R. Wurtman,et al.  Nutritional modifiers of aging brain function: use of uridine and other phosphatide precursors to increase formation of brain synapses. , 2010, Nutrition reviews.

[31]  S. Raychaudhuri,et al.  A role for human neuroglobin in apoptosis , 2010, IUBMB life.

[32]  A. Obenaus,et al.  Docosahexaenoic Acid Therapy of Experimental Ischemic Stroke , 2010, Translational Stroke Research.

[33]  J. Tordoir,et al.  Open repair for ruptured abdominal aortic aneurysm and the risk of spinal cord ischemia: review of the literature and risk-factor analysis. , 2010, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[34]  Anne M. Evans,et al.  Organization of GC/MS and LC/MS metabolomics data into chemical libraries , 2010, J. Cheminformatics.

[35]  J. Priestley,et al.  Docosahexaenoic acid prevents white matter damage after spinal cord injury. , 2010, Journal of neurotrauma.

[36]  J. Priestley,et al.  The acute administration of eicosapentaenoic acid is neuroprotective after spinal cord compression injury in rats. , 2010, Prostaglandins, leukotrienes, and essential fatty acids.

[37]  F. Pifferi,et al.  n-3 long-chain fatty acids and regulation of glucose transport in two models of rat brain endothelial cells , 2010, Neurochemistry International.

[38]  D. Radzioch,et al.  Fenretinide Promotes Functional Recovery and Tissue Protection after Spinal Cord Contusion Injury in Mice , 2010, The Journal of Neuroscience.

[39]  T. Fukuda,et al.  Spinal cord injury is not negligible after TEVAR for lower descending aorta. , 2010, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[40]  Luke Hunter,et al.  Interpreting Metabolomic Profiles using Unbiased Pathway Models , 2010, PLoS Comput. Biol..

[41]  N. Bazan Cellular and molecular events mediated by docosahexaenoic acid-derived neuroprotectin D1 signaling in photoreceptor cell survival and brain protection. , 2009, Prostaglandins, leukotrienes, and essential fatty acids.

[42]  David S. Wishart,et al.  MetaboAnalyst: a web server for metabolomic data analysis and interpretation , 2009, Nucleic Acids Res..

[43]  C. Casiano,et al.  Activation and reversal of lipotoxicity in PC12 and rat cortical cells following exposure to palmitic acid , 2009, Journal of neuroscience research.

[44]  C. Ríos,et al.  Differential time-course of the increase of antioxidant thiol-defenses in the acute phase after spinal cord injury in rats , 2009, Neuroscience Letters.

[45]  F. Weaver,et al.  Provider perspectives on soldiers with new spinal cord injuries returning from Iraq and Afghanistan. , 2009, Archives of physical medicine and rehabilitation.

[46]  B. Boden,et al.  Spinal injuries in sports. , 2008, Neurologic clinics.

[47]  V. King,et al.  A combination of intravenous and dietary docosahexaenoic acid significantly improves outcome after spinal cord injury. , 2007, Brain : a journal of neurology.

[48]  E. Roth Immune and cell modulation by amino acids. , 2007, Clinical nutrition.

[49]  E. Mazzon,et al.  Role of endogenous glutathione in the secondary damage in experimental spinal cord injury in mice , 2007, Neuroscience Letters.

[50]  C. Ríos,et al.  Acute Alterations of Glutamate, Glutamine, GABA, and Other Amino Acids After Spinal Cord Contusion in Rats , 2006, Neurochemical Research.

[51]  J. Richardson,et al.  Cytoglobin Is a Stress-responsive Hemoprotein Expressed in the Developing and Adult Brain , 2006, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[52]  V. King,et al.  Omega-3 Fatty Acids Improve Recovery, whereas Omega-6 Fatty Acids Worsen Outcome, after Spinal Cord Injury in the Adult Rat , 2006, The Journal of Neuroscience.

[53]  Charles N Serhan,et al.  A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease. , 2005, The Journal of clinical investigation.

[54]  M. Fehlings,et al.  The role of excitotoxicity in secondary mechanisms of spinal cord injury: a review with an emphasis on the implications for white matter degeneration. , 2004, Journal of neurotrauma.

[55]  Xin Wang,et al.  Neuroprotective effect of docosahexaenoic acid on glutamate-induced cytotoxicity in rat hippocampal cultures , 2003, Neuroreport.

[56]  M. Lazdunski,et al.  Linolenic acid prevents neuronal cell death and paraplegia after transient spinal cord ischemia in rats. , 2003, Journal of vascular surgery.

[57]  P. Mammen,et al.  Neuroprotection and the role of neuroglobin , 2003, The Lancet.

[58]  John D. Storey,et al.  Statistical significance for genomewide studies , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[59]  N. Bowery,et al.  Extracellular glutamine to glutamate ratio may predict outcome in the injured brain: a clinical microdialysis study in children. , 2003, Pharmacological research.

[60]  C. Hulsebosch Recent advances in pathophysiology and treatment of spinal cord injury. , 2002, Advances in physiology education.

[61]  J. Mcdonald,et al.  Spinal-cord injury , 2002, The Lancet.

[62]  I. Ikeda,et al.  Effect of dietary seal and fish oils on lipid metabolism in hamsters. , 2001, Journal of nutritional science and vitaminology.

[63]  D. McAdoo,et al.  Evidence that reversed glutamate uptake contributes significantly to glutamate release following experimental injury to the rat spinal cord , 2000, Brain Research.

[64]  M. Mattson,et al.  Impaired mitochondrial function, oxidative stress and altered antioxidant enzyme activities following traumatic spinal cord injury , 1997, Brain Research.

[65]  A. Blight,et al.  Increased levels of the excitotoxin quinolinic acid in spinal cord following contusion injury , 1993, Brain Research.

[66]  E. Major,et al.  Human microglia convert l-tryptophan into the neurotoxin quinolinic acid. , 1992, The Biochemical journal.

[67]  S. Gordon,et al.  Metabolism of glucose, glutamine, long-chain fatty acids and ketone bodies by murine macrophages. , 1986, The Biochemical journal.

[68]  Robert Tibshirani,et al.  Statistical methods for identifying differentially expressed genes in DNA microarrays. , 2003, Methods in molecular biology.

[69]  J. A. Gruner,et al.  A monitored contusion model of spinal cord injury in the rat. , 1992, Journal of neurotrauma.

[70]  B. Wittenberg,et al.  Transport of oxygen in muscle. , 1989, Annual review of physiology.