Aetiology, diagnosis, and clinical management of vulvodynia

Chronic vulvar pain or discomfort for which no obvious aetiology can be found, i.e. vulvodynia, can affect up to 16% of women, and it may be found in girls and women across all age groups and ethnicities. Most patients describe it as burning, stinging, irritation, or rawness. The symptoms may spread to the whole vulva (generalised vulvodynia) or only to part of it, such as the clitoris (clitorodynia) or the vestibule of the vagina (vestibulodynia). This condition is often underreported and underrecognised by health care providers. Vulvodynia is a significant burden to society, the health care system, the affected women, and their intimate partners. It has a negative impact on quality of life. Vulvodynia is a diagnosis of exclusion with unknown aetiology. The gynaecologist plays a key role in excluding other causes of vulvar pain, and collaborating with other health care providers to manage the patient’s pain. Although many therapeutic options are available, such as vulvar care measures, psychological approaches, local treatment, oral medications, surgical procedures, electrical nerve stimulation, and laser therapy, there is no single treatment effective for all patients. That is why individualised management is needed. An individualised, holistic, and often multidisciplinary approach is needed to effectively manage the patient’s pain and pain-related distress.

[1]  R. Adams,et al.  The American College of Obstetricians and Gynecologists , 2018, Obstetrics & Gynecology.

[2]  Maciej Zalewski,et al.  Urinary incontinence in postmenopausal women – causes, symptoms, treatment , 2019, Przeglad menopauzalny = Menopause review.

[3]  A. Dawood,et al.  Current clinical applications of platelet-rich plasma in various gynecological disorders: An appraisal of theory and practice , 2018, Clinical and experimental reproductive medicine.

[4]  S. Prendergast Pelvic Floor Physical Therapy for Vulvodynia: A Clinician's Guide. , 2017, Obstetrics and gynecology clinics of North America.

[5]  J. Bornstein,et al.  2015 ISSVD, ISSWSH and IPPS Consensus Terminology and Classification of Persistent Vulvar Pain and Vulvodynia , 2016, Obstetrics and gynecology.

[6]  L. Sadownik Etiology, diagnosis, and clinical management of vulvodynia , 2014, International journal of women's health.

[7]  Ananda Sen,et al.  Prevalence and demographic characteristics of vulvodynia in a population-based sample. , 2012, American journal of obstetrics and gynecology.

[8]  J. Paavonen,et al.  Surgical treatment of vulvar vestibulitis: a review , 2010, Acta obstetricia et gynecologica Scandinavica.

[9]  N. Bohm-Starke,et al.  Chronic stress in women with localised provoked vulvodynia , 2009, Journal of psychosomatic obstetrics and gynaecology.

[10]  S. Florell,et al.  The role of vulvar skin biopsy in the evaluation of chronic vulvar pain. , 2008, American journal of obstetrics and gynecology.

[11]  U. Nicolini,et al.  Transcutaneous electrical nerve stimulation to treat vestibulodynia: a randomised controlled trial , 2008, BJOG : an international journal of obstetrics and gynaecology.

[12]  P. Lynch,et al.  Vulvoscopy: review of a diagnostic approach requiring clarification. , 2008, The Journal of reproductive medicine.

[13]  H. Haefner Report of the International Society for the Study of Vulvovaginal Disease Terminology and Classification of Vulvodynia , 2007, Journal of lower genital tract disease.

[14]  M. Moyal-Barracco,et al.  The Vulvodynia Guideline , 2005, Journal of lower genital tract disease.

[15]  M. Couper,et al.  Pain at the Vulvar Vestibule: A Web-Based Survey , 2004, Journal of lower genital tract disease.

[16]  A. Advincula,et al.  Sexual Activities and Attitudes of Women With Vulvar Dysesthesia , 2003, Obstetrics and gynecology.

[17]  K. Hartmann,et al.  Overnight 5% Lidocaine Ointment for Treatment of Vulvar Vestibulitis , 2003, Obstetrics and gynecology.

[18]  D. Segal,et al.  Submucous infiltration of betamethasone and lidocaine in the treatment of vulvar vestibulitis. , 2003, European journal of obstetrics, gynecology, and reproductive biology.

[19]  R. Amsel,et al.  A randomized comparison of group cognitive–behavioral therapy, surface electromyographic biofeedback, and vestibulectomy in the treatment of dyspareunia resulting from vulvar vestibulitis , 2001, Pain.

[20]  P. Nyirjesy,et al.  Cromolyn cream for recalcitrant idiopathic vulvar vestibulitis: results of a placebo controlled study , 2001, Sexually transmitted infections.

[21]  L. Sadownik Clinical profile of vulvodynia patients. A prospective study of 300 patients. , 2000, The Journal of reproductive medicine.

[22]  D. Nunns,et al.  Psychological and psychosexual aspects of vulvar vestibulitis. , 1997, Genitourinary medicine.

[23]  Y. Binik,et al.  Vulvar vestibulitis syndrome: a critical review. , 1997, The Clinical journal of pain.