Quantitative determination of fluorinated alkyl substances by large-volume-injection liquid chromatography tandem mass spectrometry-characterization of municipal wastewaters.

A quantitative method was developed for the determination of fluorinated alkyl substances in municipal wastewater influents and effluents. The method consisted of centrifugation followed by large-volume injection (500 microL) of the supernatant onto a liquid chromatograph with a reverse-phase column and detection by electrospray ionization and tandem mass spectrometry. The fluorinated analytes studied include perfluoroalkyl sulfonates, fluorotelomer sulfonates, perfluorocarboxylates, and select fluorinated alkyl sulfonamides. Recoveries of the fluorinated analytes from wastewater treatment plant (WWTP) raw influents and final effluent were in the ranges of 82-100% and 86-100%, respectively. The lower limit of quantitation was 0.5 ng/L depending on the analyte. The method was applied to flow-proportional composites of raw influent and final effluent collected over a 24 h period from 10 WWTPs nationwide. Fluorinated alkyl substances were observed in wastewater at all treatment plants, and each plant exhibited unique distributions of fluorinated alkyl substances despite similarities in treatment processes. In 9 out of the 10 plants sampled, at least one class of fluorinated alkyl substances exhibited increased concentrations in the effluent as compared to the influent concentrations. In some instances, decreases in certain fluorinated analyte concentrations were observed and attributed to sorption to sludge.

[1]  Ning Wang,et al.  Aerobic biotransformation of 14C-labeled 8-2 telomer B alcohol by activated sludge from a domestic sewage treatment plant. , 2005, Environmental science & technology.

[2]  Jerald L Schnoor,et al.  Evaluation of perfluorooctane surfactants in a wastewater treatment system and in a commercial surface protection product. , 2005, Environmental science & technology.

[3]  S. Mabury,et al.  Determination of perfluorinated surfactants in surface water samples by two independent analytical techniques: liquid chromatography/tandem mass spectrometry and 19F NMR. , 2001, Analytical chemistry.

[4]  N Yamashita,et al.  Perfluorinated compounds in coastal waters of Hong Kong, South China, and Korea. , 2004, Environmental science & technology.

[5]  M. Christman,et al.  Effects of contaminant exposure on reproductive success of ospreys (Pandion haliaetus) nesting in delaware river and bay, USA , 2005, Environmental toxicology and chemistry.

[6]  J. S. Eldridge,et al.  Quantitative characterization of trace levels of PFOS and PFOA in the Tennessee River. , 2002, Environmental science & technology.

[7]  J. Flaherty,et al.  Analytical Techniques and Method Validation for the Measurement of Selected Semivolatile and Nonvolatile Organofluorochemicals in Air , 2004, Journal of occupational and environmental hygiene.

[8]  Tsuyoshi Okazawa,et al.  Analysis of perfluorinated acids at parts-per-quadrillion levels in seawater using liquid chromatography-tandem mass spectrometry. , 2004, Environmental science & technology.

[9]  Scott A Mabury,et al.  Monitoring perfluorinated surfactants in biota and surface water samples following an accidental release of fire-fighting foam into Etobicoke Creek. , 2002, Environmental science & technology.

[10]  J. Bayona,et al.  Determination of perfluorocarboxylic acids in aqueous matrices by ion-pair solid-phase microextraction-in-port derivatization-gas chromatography-negative ion chemical ionization mass spectrometry. , 2004, Journal of chromatography. A.

[11]  Paul D. Jones,et al.  Accumulation of perfluorooctane sulfonate in marine mammals. , 2001, Environmental science & technology.

[12]  C. Criddle,et al.  Quantitative determination of perfluorochemicals in sediments and domestic sludge. , 2005, Environmental science & technology.

[13]  A. Calafat,et al.  Automated solid-phase extraction and measurement of perfluorinated organic acids and amides in human serum and milk. , 2004, Environmental science & technology.

[14]  Kouji Harada,et al.  Perfluorooctanoate and Perfluorooctane Sulfonate Concentrations in Surface Water in Japan , 2004, Journal of occupational health.

[15]  Bogdan Szostek,et al.  Quantitative determination of perfluorooctanoic acid in serum and plasma by liquid chromatography tandem mass spectrometry. , 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[16]  Jerald L Schnoor,et al.  Detection of perfluorooctane surfactants in Great Lakes water. , 2004, Environmental science & technology.

[17]  S. Mabury,et al.  Perfluoroalkyl contaminants in a food web from Lake Ontario. , 2004, Environmental science & technology.

[18]  Scott A Mabury,et al.  Fluorotelomer alcohol biodegradation yields poly- and perfluorinated acids. , 2004, Environmental science & technology.

[19]  Jennifer A Field,et al.  Quantitative determination of fluorotelomer sulfonates in groundwater by LC MS/MS. , 2004, Environmental science & technology.

[20]  Scott A Mabury,et al.  Collection of airborne fluorinated organics and analysis by gas chromatography/chemical ionization mass spectrometry. , 2002, Analytical chemistry.

[21]  Scott A Mabury,et al.  Polyfluorinated telomer alcohols and sulfonamides in the North American troposphere. , 2004, Environmental science & technology.

[22]  C. Criddle,et al.  Defluorination of Organofluorine Sulfur Compounds by Pseudomonas Sp. Strain D2 , 1998 .

[23]  Nobuyoshi Yamashita,et al.  A survey of perfluorooctane sulfonate and related perfluorinated organic compounds in water, fish, birds, and humans from Japan. , 2003, Environmental science & technology.

[24]  K. Hansen,et al.  Compound-specific, quantitative characterization of organic fluorochemicals in biological matrices. , 2001, Environmental science & technology.

[25]  Scott A Mabury,et al.  Identification of long-chain perfluorinated acids in biota from the Canadian Arctic. , 2004, Environmental science & technology.

[26]  E. Kissa.  Fluorinated surfactants : synthesis, properties, applications , 1994 .