An ultrasound-based approach for the synthesis of indoles under Pd/C catalysis

[1]  M. Palumbo,et al.  Aza-isoindolo and isoindolo-azaquinoxaline derivatives with antiproliferative activity. , 2015, European journal of medicinal chemistry.

[2]  C. Ciancimino,et al.  3-[4-(1H-Indol-3-yl)-1,3-thiazol-2-yl]-1H-pyrrolo[2,3-b]pyridines, Nortopsentin Analogues with Antiproliferative Activity , 2015, Marine drugs.

[3]  N. Zaffaroni,et al.  Synthesis and antiproliferative activity of substituted 3[2-(1H-indol-3-yl)- 1,3-thiazol-4-yl]-1H-pyrrolo[3,2-b]pyridines, marine alkaloid nortopsentin analogues. , 2014, Current medicinal chemistry.

[4]  Arunasree M. Kalle,et al.  Synthesis of indole based novel small molecules and their in vitro anti-proliferative effects on various cancer cell lines , 2014 .

[5]  David J. Miller,et al.  Optimization of novel indole-2-carboxamide inhibitors of neurotropic alphavirus replication. , 2013, Journal of medicinal chemistry.

[6]  Chung Hyeok Kim,et al.  Biomedical Importance of Indoles , 2013, Molecules.

[7]  K. Mukkanti,et al.  Novel N-indolylmethyl substituted olanzapine derivatives: their design, synthesis and evaluation as PDE4B inhibitors. , 2013, Organic & biomolecular chemistry.

[8]  A. McCluskey,et al.  Development of second-generation indole-based dynamin GTPase inhibitors. , 2013, Journal of medicinal chemistry.

[9]  V. S. Rao,et al.  A new cascade reaction: concurrent construction of six and five membered rings leading to novel fused quinazolinones. , 2012, Organic & biomolecular chemistry.

[10]  C. Moody,et al.  Two-step route to indoles and analogues from haloarenes: a variation on the Fischer indole synthesis. , 2012, The Journal of organic chemistry.

[11]  J. Iqbal,et al.  A new route to indoles via in situ desilylation–Sonogashira strategy: identification of novel small molecules as potential anti-tuberculosis agents , 2011 .

[12]  P. Brun,et al.  Synthesis of Triazenoazaindoles: a New Class of Triazenes with Antitumor Activity , 2011, ChemMedChem.

[13]  J. Iqbal,et al.  Sequential coupling/desilylation-coupling/cyclization in a single pot under Pd/C-Cu catalysis: synthesis of 2-(hetero)aryl indoles. , 2011, Organic & biomolecular chemistry.

[14]  P. Diana,et al.  Synthesis of the new ring system pyrrolizino[2,3-b]indol-4(5H)-one , 2011 .

[15]  D. Miller,et al.  Microwave-assisted synthesis of medicinally relevant indoles. , 2011, Current medicinal chemistry.

[16]  G. Fabrizi,et al.  Copper catalysis in the construction of indole and benzo[b]furan rings. , 2011, Organic & biomolecular chemistry.

[17]  G. Palmisano,et al.  Synthesis of Indole Derivatives with Biological Activity by Reactions Between Unsaturated Hydrocarbons and N-Aromatic Precursors , 2010 .

[18]  Y. Monguchi,et al.  Palladium on carbon-catalyzed synthesis of 2- and 2,3-substituted indoles under heterogeneous conditions. , 2010, Organic & biomolecular chemistry.

[19]  M. Pal Palladium-Catalyzed Alkynylationof Aryl and Hetaryl Halides: A Journey from Conventional PalladiumComplexes or Salts to Palladium/Carbon , 2009 .

[20]  F. J. Fañanás,et al.  Recent advances in the synthesis of indole and quinoline derivatives through cascade reactions. , 2009, Chemistry, an Asian journal.

[21]  Michael Reggelin,et al.  Syntheses of novel 2,3-diaryl-substituted 5-cyano-4-azaindoles exhibiting c-Met inhibition activity. , 2009, Bioorganic & medicinal chemistry letters.

[22]  M. Beller,et al.  Catalytic Synthesis of Indoles from Alkynes , 2008 .

[23]  Yoshinori Yamamoto,et al.  Coinage metal-assisted synthesis of heterocycles. , 2008, Chemical reviews.

[24]  E. Hickey,et al.  Preparation of 3-substituted-2-pyridin-2-ylindoles: regioselectivity of Larock’s indole annulation with 2-alkynylpyridines , 2008 .

[25]  J. Khinast,et al.  Pd-leaching and Pd-removal in Pd/C-catalyzed Suzuki couplings , 2007 .

[26]  L. Ackermann Catalytic Arylations with Challenging Substrates: From Air-Stable HASPO Preligands to Indole Syntheses and C-H-Bond Functionalizations , 2007 .

[27]  Jeffrey T. Kuethe,et al.  Practical methodologies for the synthesis of indoles. , 2006, Chemical reviews.

[28]  Giancarlo Cravotto,et al.  Power ultrasound in organic synthesis: moving cavitational chemistry from academia to innovative and large-scale applications. , 2006, Chemical Society reviews.

[29]  G. Fabrizi,et al.  Synthesis and functionalization of indoles through palladium-catalyzed reactions. , 2005, Chemical reviews.

[30]  Ji-tai Li,et al.  Some Applications of Ultrasound Irradiation in Organic Synthesis , 2005 .

[31]  M. Pal,et al.  Synthesis of 2-Substituted Indoles via Pd/C-Catalyzed Reaction in Water , 2004 .

[32]  C. Broka,et al.  Preparation of 3-arylmethylindoles as selective COX-2 inhibitors , 2004 .

[33]  M. Pal,et al.  A direct access to 3-(2-Oxoalkyl)indoles via aluminum chloride induced C-C bond formation. , 2004, The Journal of organic chemistry.

[34]  R. Larock,et al.  Synthesis of Heterocycles via Palladium π-Olefin and π-Alkyne Chemistry , 2004 .

[35]  E. Hamel,et al.  One-pot synthesis of benzo[b]furan and indole inhibitors of tubulin polymerization. , 2002, Journal of medicinal chemistry.

[36]  S. Nishimura Handbook of Heterogeneous Catalytic Hydrogenation for Organic Synthesis , 2001 .

[37]  D. Marko,et al.  Methoxy-substituted 3-formyl-2-phenylindoles inhibit tubulin polymerization. , 1998, Journal of medicinal chemistry.

[38]  R. Larock,et al.  Synthesis of 2,3-Disubstituted Indoles via Palladium-Catalyzed Annulation of Internal Alkynes , 1998 .

[39]  F. Ujjainwalla,et al.  Synthesis of 5-, 6- and 7-azaindoles via palladium-catalyzed heteroannulation of internal alkynes , 1998 .

[40]  S. Davidsen,et al.  TRANSITION METAL CATALYZED SYNTHESIS OF 5-AZAINDOLES , 1998 .

[41]  Sang Sun Park,et al.  A facile synthesis of 2,3-disubstituted pyrrolo[2,3-b]pyridines via palladium-catalyzed heteroannulation with internal alkynes , 1998 .

[42]  A. Fürstner,et al.  "Site Selective" Formation of Low-Valent Titanium Reagents: An "Instant" Procedure for the Reductive Coupling of Oxo Amides to Indoles , 1994 .

[43]  S. Gronowitz,et al.  A novel approach to bz-substituted tryptophans via Pd-catalysed coupling / annulation. , 1993 .

[44]  A. Wilhelm,et al.  Effects of ultrasound emitter type and power on a heterogeneous reaction , 1992 .

[45]  R. Larock,et al.  Synthesis of indoles via palladium-catalyzed heteroannulation of internal alkynes , 1991 .

[46]  R. Sundberg The chemistry of indoles , 1970 .

[47]  F. Hart,et al.  Indomethacin: A New Non-steroid Anti-inflammatory Agent , 1963, British medical journal.