Parkinson disease prediction using intrinsic mode function based features from speech signal

Abstract Parkinson's disease (PD) is a progressive neurological disorder prevalent in old age. Past studies have shown that speech can be used as an early marker for identification of PD. It affects a number of speech components such as phonation, speech intensity, articulation, and respiration, which alters the speech intelligibility. Speech feature extraction and classification always have been challenging tasks due to the existence of non-stationary and discontinuity in the speech signal. In this study, empirical mode decomposition (EMD) based features are demonstrated to capture the speech characteristics. A new feature, intrinsic mode function cepstral coefficient (IMFCC) is proposed to efficiently represent the characteristics of Parkinson speech. The performances of proposed features are assessed with two different datasets: dataset-1 and dataset-2 each having 20 normal and 25 Parkinson affected peoples. From the results, it is demonstrated that the proposed intrinsic mode function cepstral coefficient feature provides superior classification accuracy in both datasets. There is a significant increase of 10–20% in accuracy compared to the standard acoustic and Mel-frequency cepstral coefficient (MFCC) features.

[1]  Aboul Ella Hassanien,et al.  Improved diagnosis of Parkinson's disease using optimized crow search algorithm , 2018, Comput. Electr. Eng..

[2]  Alain Ghio,et al.  Measurement of Tremor in the Voices of Speakers with Parkinson's Disease , 2015, ICNLSP.

[3]  Jesús Francisco Vargas-Bonilla,et al.  Spectral and cepstral analyses for Parkinson's disease detection in Spanish vowels and words , 2015, Expert Syst. J. Knowl. Eng..

[4]  Michal Novotný,et al.  High-Accuracy Voice-Based Classification Between Patients With Parkinson’s Disease and Other Neurological Diseases May Be an Easy Task With Inappropriate Experimental Design , 2017, IEEE Transactions on Neural Systems and Rehabilitation Engineering.

[5]  Max A. Little,et al.  Suitability of Dysphonia Measurements for Telemonitoring of Parkinson's Disease , 2008, IEEE Transactions on Biomedical Engineering.

[6]  N. Arunkumar,et al.  Optimized cuttlefish algorithm for diagnosis of Parkinson’s disease , 2018, Cognitive Systems Research.

[7]  M. Dougherty,et al.  Cepstral separation difference : a novel approach for speech impairment quantification in Parkinson’s disease , 2014 .

[8]  Elmar Nöth,et al.  Detection of persons with Parkinson's disease by acoustic, vocal, and prosodic analysis , 2011, 2011 IEEE Workshop on Automatic Speech Recognition & Understanding.

[9]  Ute Ritterfeld,et al.  Game-Based Speech Rehabilitation for People with Parkinson's Disease , 2017, HCI.

[10]  A. Tafreshi,et al.  Speech disorders in Parkinson's disease: pathophysiology, medical management and surgical approaches. , 2018, Neurodegenerative disease management.

[11]  P. Dhanalakshmi,et al.  Classification of audio signals using AANN and GMM , 2011, Appl. Soft Comput..

[12]  Raghunath S. Holambe,et al.  Speaker Identification Based on Robust AM-FM Features , 2009, 2009 Second International Conference on Emerging Trends in Engineering & Technology.

[13]  Shrikanth S. Narayanan,et al.  A variable frame length and rate algorithm based on the spectral kurtosis measure for speaker verification , 2010, INTERSPEECH.

[14]  Ahmed Hammouch,et al.  Voice analysis for detecting patients with Parkinson's disease using the hybridization of the best acoustic features , 2016 .

[15]  Jesús Francisco Vargas-Bonilla,et al.  New Spanish speech corpus database for the analysis of people suffering from Parkinson’s disease , 2014, LREC.

[16]  Juan Ignacio Godino-Llorente,et al.  Analysis of speaker recognition methodologies and the influence of kinetic changes to automatically detect Parkinson's Disease , 2018, Appl. Soft Comput..

[17]  Sitanshu Sekhar Sahu,et al.  Detection of Parkinson Disease Using Variational Mode Decomposition of Speech Signal , 2018, 2018 International Conference on Communication and Signal Processing (ICCSP).

[18]  Meysam Asgari,et al.  Fully automated assessment of the severity of Parkinson's disease from speech , 2015, Comput. Speech Lang..

[19]  Clayton R. Pereira,et al.  Handwritten dynamics assessment through convolutional neural networks: An application to Parkinson's disease identification , 2018, Artif. Intell. Medicine.

[20]  Clayton R. Pereira,et al.  A survey on computer-assisted Parkinson's Disease diagnosis , 2019, Artif. Intell. Medicine.

[21]  Max A. Little,et al.  Novel Speech Signal Processing Algorithms for High-Accuracy Classification of Parkinson's Disease , 2012, IEEE Transactions on Biomedical Engineering.

[22]  Gabriel Rilling,et al.  Empirical mode decomposition as a filter bank , 2004, IEEE Signal Processing Letters.

[23]  Sazali Yaacob,et al.  Classification of speech dysfluencies with MFCC and LPCC features , 2012, Expert Syst. Appl..

[24]  Fikret S. Gürgen,et al.  Collection and Analysis of a Parkinson Speech Dataset With Multiple Types of Sound Recordings , 2013, IEEE Journal of Biomedical and Health Informatics.

[25]  Hugo Leonardo Rufiner,et al.  Empirical mode decomposition. Spectral properties in normal and pathological voices , 2009 .

[26]  Carlos J. Pérez,et al.  Diagnosis and Tracking of ParkinsonâÂÂs Disease by using AutomaticallyExtracted Acoustic Features , 2016 .

[27]  J. R. Orozco-Arroyave,et al.  Automatic detection of Parkinson's disease using noise measures of speech , 2013, Symposium of Signals, Images and Artificial Vision - 2013: STSIVA - 2013.

[28]  Jirí Mekyska,et al.  Parkinson Disease Detection from Speech Articulation Neuromechanics , 2017, Front. Neuroinform..

[29]  J R Orozco-Arroyave,et al.  Automatic detection of Parkinson's disease in running speech spoken in three different languages. , 2016, The Journal of the Acoustical Society of America.

[30]  Theodoros Giannakopoulos,et al.  Introduction to Audio Analysis: A MATLAB® Approach , 2014 .

[31]  Gastón Schlotthauer Voice Fundamental Frequency Extraction Algorithm Based on Ensemble Empirical Mode Decomposition and Entropies , 2009 .

[32]  Roman Cmejla,et al.  Automatic Evaluation of Articulatory Disorders in Parkinson’s Disease , 2014, IEEE/ACM Transactions on Audio, Speech, and Language Processing.

[33]  Evžen Růžička,et al.  Automated analysis of connected speech reveals early biomarkers of Parkinson’s disease in patients with rapid eye movement sleep behaviour disorder , 2017, Scientific Reports.

[34]  Mehrbakhsh Nilashi,et al.  A hybrid intelligent system for the prediction of Parkinson's Disease progression using machine learning techniques , 2017 .

[35]  Germán Castellanos-Domínguez,et al.  Automatic Detection of Pathological Voices Using Complexity Measures, Noise Parameters, and Mel-Cepstral Coefficients , 2011, IEEE Transactions on Biomedical Engineering.

[36]  Bhavani M. Thuraisingham,et al.  Face Recognition Using Multiple Classifiers , 2006, 2006 18th IEEE International Conference on Tools with Artificial Intelligence (ICTAI'06).

[37]  Bayya Yegnanarayana,et al.  Combining evidence from residual phase and MFCC features for speaker recognition , 2006, IEEE Signal Processing Letters.

[38]  Rajib Sharma,et al.  Analysis of the Intrinsic Mode Functions for Speaker Information , 2017, Speech Commun..

[39]  Danial Taheri Far,et al.  Speech Analysis for Diagnosis of Parkinson’s Disease Using Genetic Algorithm and Support Vector Machine , 2014 .

[40]  Elmar Nöth,et al.  Speaker models for monitoring Parkinson's disease progression considering different communication channels and acoustic conditions , 2018, Speech Commun..

[41]  N. Huang,et al.  The empirical mode decomposition and the Hilbert spectrum for nonlinear and non-stationary time series analysis , 1998, Proceedings of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences.

[42]  Clayton R. Pereira,et al.  A recurrence plot-based approach for Parkinson's disease identification , 2019, Future Gener. Comput. Syst..

[43]  A. Roberts,et al.  Information Content and Efficiency in the Spoken Discourse of Individuals With Parkinson's Disease. , 2018, Journal of speech, language, and hearing research : JSLHR.

[44]  Petri Toiviainen,et al.  MIR in Matlab (II): A Toolbox for Musical Feature Extraction from Audio , 2007, ISMIR.

[45]  E. Růžička,et al.  Quantitative acoustic measurements for characterization of speech and voice disorders in early untreated Parkinson's disease. , 2011, The Journal of the Acoustical Society of America.

[46]  Antanas Verikas,et al.  Detecting Parkinson’s disease from sustained phonation and speech signals , 2017, PloS one.

[47]  Rajib Sharma,et al.  Detection of the Glottal Closure Instants Using Empirical Mode Decomposition , 2018, Circuits Syst. Signal Process..