Expression of PDGF-β receptor, EGF receptor, and receptor adaptor protein Shc in rat osteoblasts during spaceflight

[1]  R. Turner,et al.  Programmed administration of parathyroid hormone increases bone formation and reduces bone loss in hindlimb-unloaded ovariectomized rats. , 1998, Endocrinology.

[2]  T. Gudermann,et al.  Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic, acid-stimulated mitogenic activity in L cells. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[3]  H. Akiyama,et al.  Spaceflight modulates insulin-like growth factor binding proteins and glucocorticoid receptor in osteoblasts. , 1998, Journal of applied physiology.

[4]  M Hughes-Fulford,et al.  Effects of microgravity on osteoblast growth. , 1998, Gravitational and space biology bulletin : publication of the American Society for Gravitational and Space Biology.

[5]  S. Spiegel,et al.  Divergence in Signal Transduction Pathways of Platelet-derived Growth Factor (PDGF) and Epidermal Growth Factor (EGF) Receptors , 1997, The Journal of Biological Chemistry.

[6]  T. Hunter Oncoprotein Networks , 1997, Cell.

[7]  H. Akiyama,et al.  An improved quantitative RT-PCR fluorescent method for analysis of gene transcripts in the STS-65 space shuttle experiment. , 1996, Journal of biotechnology.

[8]  H. Akiyama,et al.  Microgravity induces prostaglandin E2 and interleukin-6 production in normal rat osteoblasts: role in bone demineralization. , 1996, Journal of biotechnology.

[9]  M. Haussler,et al.  New understanding of the molecular mechanism of receptor-mediated genomic actions of the vitamin D hormone. , 1995, Bone.

[10]  K. Funa,et al.  Isolation and characterization of the mouse PDGF beta-receptor promoter. , 1995, Biochemical and biophysical research communications.

[11]  M. Polan,et al.  Gonadal steroids modulate interleukin-1 receptor antagonist mRNA expression in cultured human monocytes. , 1995, Biochemical and biophysical research communications.

[12]  J. Schlessinger,et al.  Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor , 1994, Molecular and cellular biology.

[13]  L. Quarles,et al.  Molecular to pharmacologic control of osteoblast proliferation and differentiation , 1994, Journal of cellular biochemistry.

[14]  R. Howells,et al.  Sequence of the 5'-flanking region of the rat c-fos proto-oncogene. , 1994, Gene.

[15]  T Pawson,et al.  Direct interaction between Shc and the platelet-derived growth factor beta-receptor. , 1994, The Journal of biological chemistry.

[16]  Takato O. Yoshida,et al.  The biased Vγ gene usage in the synovial fluid of patients with rheumatoid arthritis , 1994 .

[17]  J. Boonstra,et al.  Inhibition of EGF-induced signal transduction by microgravity is independent of EGF receptor redistribution in the plasma membrane of human A431 cells. , 1993, Experimental cell research.

[18]  J. Kato,et al.  Expression of estrogen receptor in the rat brain: Detection of its mRNA using reverse transcription-polymerase chain reaction , 1992, The Journal of Steroid Biochemistry and Molecular Biology.

[19]  J. den Hertog,et al.  Nuclear responses to protein kinase C signal transduction are sensitive to gravity changes. , 1991, Experimental cell research.

[20]  M. Simon,et al.  Determining transcript number using the polymerase chain reaction: Pgk-2, mP2, and PGK-2 transgene mRNA levels during spermatogenesis. , 1991, Nucleic acids research.

[21]  S. Kliewer,et al.  Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor , 1990, Cell.

[22]  K. Yamamoto,et al.  Transcription factor interactions: selectors of positive or negative regulation from a single DNA element. , 1990, Science.

[23]  J. den Hertog,et al.  Microgravity decreases c-fos induction and serum response element activity. , 1990, Journal of cell science.

[24]  J. Chow,et al.  Role for parathyroid hormone in mechanical responsiveness of rat bone. , 1998, The American journal of physiology.

[25]  G. Schultz,et al.  Analysis of messenger RNA. , 1993, Methods in enzymology.

[26]  A. Riggs,et al.  Quantitative analysis of messenger RNA levels: reverse transcription-polymerase chain reaction single nucleotide primer extension assay. , 1993, Methods in enzymology.

[27]  J. Yin,et al.  Glucocorticoid-mediated down regulation of c-fos mRNA in C6 glioma cells: lack of correlation with proenkephalin mRNA. , 1992, Brain Research. Molecular Brain Research.

[28]  S. Arnaud,et al.  Skeletal responses to spaceflight. , 1991, Advances in space biology and medicine.