HMGCS1 Promotes male differentiation of chicken embryos by regulating the generate of cholesterol

Gender research shows excellent significance in the breeding and production of poultry, achieving the actual needs of poultry through targeted gender regulation could increase economic benefits. Ho...

[1]  G. Hotamisligil,et al.  NRF1 Is an ER Membrane Sensor that Is Central to Cholesterol Homeostasis , 2017, Cell.

[2]  A. Sinclair,et al.  Overexpression of Aromatase Alone is Sufficient for Ovarian Development in Genetically Male Chicken Embryos , 2013, PloS one.

[3]  P. Koopman,et al.  Sry: the master switch in mammalian sex determination , 2010, Development.

[4]  A. Sinclair,et al.  The avian Z-linked gene DMRT1 is required for male sex determination in the chicken , 2009, Nature.

[5]  C. Vock,et al.  Transcriptional Regulation of HMG-CoA Synthase and HMG-CoA Reductase Genes by Human ACBP , 2008, Cellular Physiology and Biochemistry.

[6]  R. Braun,et al.  Hormonal regulation of testicular steroid and cholesterol homeostasis. , 2008, Molecular endocrinology.

[7]  A. Sinclair,et al.  Sex determination: insights from the chicken. , 2004, BioEssays : news and reviews in molecular, cellular and developmental biology.

[8]  Shuichi Asakawa,et al.  DMY is a Y-specific DM-domain gene required for male development in the medaka fish , 2002, Nature.

[9]  E. Decuypere,et al.  Developmental endocrinology of the reproductive axis in the chicken embryo. , 2002, Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.

[10]  A. Elbrecht,et al.  Aromatase enzyme activity and sex determination in chickens. , 1992, Science.

[11]  H. Miziorko,et al.  Avian liver 3-hydroxy-3-methylglutaryl-CoA synthase: distinct genes encode the cholesterogenic and ketogenic isozymes. , 1990, Archives of biochemistry and biophysics.

[12]  W. Engel,et al.  Appearance of H–W (H–Y) antigen in the gonads of oestradiol sex-reversed male chicken embryos , 1979, Nature.