Anti-cancer effects of Piper nigrum via inducing multiple molecular signaling in vivo and in vitro.

[1]  P. Boonyaphiphat,et al.  Anticancer and Cancer Prevention Effects of Piperine-Free Piper nigrum Extract on N-nitrosomethylurea-Induced Mammary Tumorigenesis in Rats , 2015, Cancer Prevention Research.

[2]  A. Rasedee,et al.  Oxidative Stress-Mediated Apoptosis Induced by Ethanolic Mango Seed Extract in Cultured Estrogen Receptor Positive Breast Cancer MCF-7 Cells , 2015, International journal of molecular sciences.

[3]  Zu-hua Gao,et al.  Riccardin D, a Macrocyclic Bisbibenzy, Inhibits Human Breast Cancer Growth through the Suppression of Telomerase Activity , 2014, Basic & clinical pharmacology & toxicology.

[4]  P. Graidist,et al.  Cytotoxicity Screening of Plants of Genus Piper in Breast Cancer Cell Lines , 2014 .

[5]  Mallika Alvala,et al.  Piperlongumine, an alkaloid causes inhibition of PI3 K/Akt/mTOR signaling axis to induce caspase-dependent apoptosis in human triple-negative breast cancer cells , 2014, Apoptosis.

[6]  P. Graidist,et al.  Correlation of Wilms' tumor 1 isoforms with HER2 and ER-α and its oncogenic role in breast cancer. , 2014, Anticancer research.

[7]  T. K. Goswami,et al.  Piper nigrum and Piperine: An Update , 2013, Phytotherapy research : PTR.

[8]  L. Costa-Lotufo,et al.  Overview of the therapeutic potential of piplartine (piperlongumine). , 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[9]  H. Yu,et al.  Pipernonaline from Piper longum Linn. induces ROS-mediated apoptosis in human prostate cancer PC-3 cells. , 2013, Biochemical and biophysical research communications.

[10]  P. Cheung,et al.  Two-dimensional gel electrophoresis analysis of mycelial cells treated with Tween 80: differentially expressed protein related to enhanced metabolite production. , 2012, Journal of agricultural and food chemistry.

[11]  M. Mazzone,et al.  Growing tumor vessels: more than one way to skin a cat - implications for angiogenesis targeted cancer therapies. , 2011, Molecular aspects of medicine.

[12]  J. Qiu,et al.  Inhibitive effect of cremophor RH40 or tween 80-based self-microemulsiflying drug delivery system on cytochrome P450 3A enzymes in murine hepatocytes , 2010, Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.

[13]  M. Narukawa,et al.  Activation of TRPV1 and TRPA1 by Black Pepper Components , 2010, Bioscience, biotechnology, and biochemistry.

[14]  K. Podar,et al.  A therapeutic role for targeting c-Myc/Hif-1-dependent signaling pathways. , 2010, Cell cycle.

[15]  S. Badve,et al.  Oestrogen-receptor-positive breast cancer: towards bridging histopathological and molecular classifications , 2008, Journal of Clinical Pathology.

[16]  M. Mesić,et al.  Measurement of malondialdehyde (MDA) level in rat plasma after simvastatin treatment using two different analytical methods , 2008 .

[17]  U. Jeschke,et al.  Expression of E-cadherin in human ductal breast cancer carcinoma in situ, invasive carcinomas, their lymph node metastases, their distant metastases, carcinomas with recurrence and in recurrence. , 2007, Anticancer research.

[18]  Yi Yan Yang,et al.  Multifunctional Core/Shell Nanoparticles Self‐Assembled from pH‐Induced Thermosensitive Polymers for Targeted Intracellular Anticancer Drug Delivery , 2007 .

[19]  Shishir Shishodia,et al.  Molecular targets of dietary agents for prevention and therapy of cancer. , 2006, Biochemical pharmacology.

[20]  Weili Ma,et al.  p53-Dependent Transcriptional Repression of c-myc Is Required for G1 Cell Cycle Arrest , 2005, Molecular and Cellular Biology.

[21]  A. Szallasi.  Piperine: researchers discover new flavor in an ancient spice. , 2005, Trends in pharmacological sciences.

[22]  Xin Lu,et al.  Gene expression profiling of NMU-induced rat mammary tumors: cross species comparison with human breast cancer. , 2005, Carcinogenesis.

[23]  K. Selvendiran,et al.  Protective effect of piperine on benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice. , 2004, Clinica chimica acta; international journal of clinical chemistry.

[24]  C. Harris,et al.  p53: 25 years after its discovery. , 2004, Trends in pharmacological sciences.

[25]  Gerhard Christofori,et al.  Cell adhesion and signalling by cadherins and Ig-CAMs in cancer , 2004, Nature Reviews Cancer.

[26]  G. Taraboletti,et al.  Matrix metalloproteinases (MMP9 and MMP2) induce the release of vascular endothelial growth factor (VEGF) by ovarian carcinoma cells: implications for ascites formation. , 2003, Cancer research.

[27]  Ivan Stamenkovic,et al.  Extracellular matrix remodelling: the role of matrix metalloproteinases , 2003, The Journal of pathology.

[28]  E. van Marck,et al.  Inflammatory breast cancer shows angiogenesis with high endothelial proliferation rate and strong E-cadherin expression , 2003, British Journal of Cancer.

[29]  D. Liao,et al.  c-Myc in breast cancer. , 2000, Endocrine-related cancer.

[30]  L. Marnett.  Lipid peroxidation-DNA damage by malondialdehyde. , 1999, Mutation research.

[31]  C. Olsen,et al.  Phytochemistry of the genus Piper , 1997 .

[32]  J Piper,et al.  Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[33]  W. Epstein,et al.  Isolation of piperine from black pepper , 1993 .

[34]  M. A. Khan,et al.  Biological role of Piper nigrum L. (Black pepper): A review , 2012 .

[35]  Gayatri Nahak.  Phytochemical Evaluation and Antioxidant activity of Piper cubeba and Piper nigrum , 2011 .

[36]  G. Kuttan,et al.  Effect of piperine on the inhibition of lung metastasis induced B16F-10 melanoma cells in mice , 2004, Clinical & Experimental Metastasis.

[37]  A. Bast,et al.  Using telemetry to study the effect of protectors on doxorubicin-induced cardiotoxicity in freely moving mice. , 1999 .

[38]  V. Rotter,et al.  Introduction: p53 – the first twenty years , 1999, Cellular and Molecular Life Sciences CMLS.

[39]  M. Sehested,et al.  The solvents cremophor EL and Tween 80 modulate daunorubicin resistance in the multidrug resistant Ehrlich ascites tumor. , 1990, Cancer communications.

[40]  R. Johnson,et al.  Uptake and retention of adriamycin and daunorubicin by sensitive and anthracycline-resistant sublines of P388 leukemia. , 1978, Biochemical pharmacology.