Allopurinol attenuates rhabdomyolysis-associated acute kidney injury: Renal and muscular protection.

[1]  D. Wilson,et al.  Glycerol induced hemoglobinuric acute renal failure in the rat. II. The experimental model, predisposing factors, and pathophysiologic features. , 1967, Nephron.

[2]  T. Kurtz,et al.  Cardiac Output and Renal Blood Flow in Glycerol‐Induced Acute Renal Failure in the Rat , 1977, Circulation research.

[3]  B. Stillman,et al.  Functional identity of proliferating cell nuclear antigen and a DNA polymerase-δ auxiliary protein , 1987, Nature.

[4]  B. Stillman,et al.  The cell-cycle regulated proliferating cell nuclear antigen is required for SV40 DNA replication in vitro , 1987, Nature.

[5]  B. Stillman,et al.  Coordinated leading and lagging strand synthesis during SV40 DNA replication in vitro requires PCNA , 1988, Cell.

[6]  A. Harken,et al.  Xanthine oxidase produces hydrogen peroxide which contributes to reperfusion injury of ischemic, isolated, perfused rat hearts. , 1988, The Journal of clinical investigation.

[7]  Y. Hellsten,et al.  Indication of in vivo xanthine oxidase activity in human skeletal muscle during exercise. , 1988, Acta physiologica Scandinavica.

[8]  J. Morrow,et al.  A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[9]  B. Freeman,et al.  Circulating xanthine oxidase: potential mediator of ischemic injury. , 1990, The American journal of physiology.

[10]  S. Shah,et al.  Role of glutathione in an animal model of myoglobinuric acute renal failure. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[11]  J. Smialek,et al.  Clinical spectrum of accidental hemlock poisoning: neurotoxic manifestations, rhabdomyolysis and acute tubular necrosis. , 1991, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[12]  Graves Ej,et al.  Detailed diagnoses and procedures, National Hospital Discharge Survey, 1994. , 1997, Vital and health statistics. Series 13, Data from the National Health Survey.

[13]  G. Vercellotti,et al.  Induction of heme oxygenase is a rapid, protective response in rhabdomyolysis in the rat. , 1992, The Journal of clinical investigation.

[14]  Hui Zhang,et al.  D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA , 1992, Cell.

[15]  M. Lemma,et al.  Improvement of Cardiac Function by Allopurinol in Patients Undergoing Cardiac Surgery , 1995, Journal of cardiovascular pharmacology.

[16]  Sidhartha Tan,et al.  Circulating xanthine oxidase in human ischemia reperfusion. , 1995, Southern medical journal.

[17]  R. Zager,et al.  Iron, heme oxygenase, and glutathione: effects on myohemoglobinuric proximal tubular injury. , 1995, Kidney international.

[18]  R. Zager.  Heme protein-induced tubular cytoresistance: expression at the plasma membrane level. , 1995, Kidney international.

[19]  R. Zager,et al.  Rhabdomyolysis and myohemoglobinuric acute renal failure. , 1996, Kidney international.

[20]  S. Bigler,et al.  Synergistic renal protection by combining alkaline-diuresis with lipid peroxidation inhibitors in rhabdomyolysis: possible interaction between oxidant and non-oxidant mechanisms. , 1996, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[21]  J. Megyesi,et al.  The p53-independent activation of transcription of p21 WAF1/CIP1/SDI1 after acute renal failure. , 1996, The American journal of physiology.

[22]  J. Morrow,et al.  A nomenclature system for the isoprostanes. , 1997, Prostaglandins.

[23]  J. Megyesi,et al.  Induction of p21WAF1/CIP1/SDI1 in kidney tubule cells affects the course of cisplatin-induced acute renal failure. , 1998, The Journal of clinical investigation.

[24]  V. Darley-Usmar,et al.  Nitrosation of Uric Acid by Peroxynitrite , 1998, The Journal of Biological Chemistry.

[25]  J. Morrow,et al.  A Causative Role for Redox Cycling of Myoglobin and Its Inhibition by Alkalinization in the Pathogenesis and Treatment of Rhabdomyolysis-induced Renal Failure* , 1998, The Journal of Biological Chemistry.

[26]  J. Hughes,et al.  Elevated Uric Acid Increases Blood Pressure in the Rat by a Novel Crystal-Independent Mechanism , 2001, Hypertension.

[27]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[28]  H. Ishizaka,et al.  Effect of Allopurinol Pretreatment on Free Radical Generation after Primary Coronary Angioplasty for Acute Myocardial Infarction , 2003, Journal of cardiovascular pharmacology.

[29]  J. Sastre,et al.  Allopurinol and markers of muscle damage among participants in the Tour de France. , 2003, JAMA.

[30]  A. Rees,et al.  Macrophages and the kidney , 2004, Current opinion in nephrology and hypertension.

[31]  D. Galaris,et al.  Uric acid and oxidative stress. , 2005, Current pharmaceutical design.

[32]  E. Block,et al.  Hyperuricemia induces endothelial dysfunction. , 2005, Kidney international.

[33]  P. Stoward,et al.  The histochemical localization of xanthine oxidase , 1978, The Histochemical Journal.

[34]  D. Harrison,et al.  Interactions of peroxynitrite with uric acid in the presence of ascorbate and thiols: implications for uncoupling endothelial nitric oxide synthase. , 2005, Biochemical pharmacology.

[35]  A. Gartel,et al.  Lost in transcription: p21 repression, mechanisms, and consequences. , 2005, Cancer research.

[36]  K. Badr,et al.  Isoprostanes and the kidney. , 2005, Antioxidants & redox signaling.

[37]  J. B. D. de Faria,et al.  Role of caspases on cell death, inflammation, and cell cycle in glycerol-induced acute renal failure. , 2006, Kidney international.

[38]  C. Szabó,et al.  Therapeutic Effects of Xanthine Oxidase Inhibitors: Renaissance Half a Century after the Discovery of Allopurinol , 2006, Pharmacological Reviews.

[39]  T. Nakagawa,et al.  Serum uric acid: a risk factor and a target for treatment? , 2006, Journal of the American Society of Nephrology : JASN.

[40]  R. Volpini,et al.  Effects of resveratrol on glycerol-induced renal injury. , 2007, Life sciences.

[41]  T. Nakagawa,et al.  Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress. , 2007, American journal of physiology. Cell physiology.

[42]  T. Nakagawa,et al.  Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia. , 2008, American journal of physiology. Renal physiology.

[43]  Kyle R. Eberlin,et al.  Development of reproducible histologic injury severity scores: skeletal muscle reperfusion injury. , 2008, Surgery.

[44]  A. Struthers,et al.  Role of urate, xanthine oxidase and the effects of allopurinol in vascular oxidative stress , 2009, Vascular health and risk management.

[45]  J. Megyesi,et al.  The cell cycle and acute kidney injury. , 2009, Kidney international.

[46]  E. Poch,et al.  Rhabdomyolysis and acute kidney injury. , 2009, The New England journal of medicine.

[47]  J. McNeill,et al.  To scale or not to scale: the principles of dose extrapolation , 2009, British journal of pharmacology.

[48]  E. Homsi,et al.  p53-Mediated Oxidative Stress and Tubular Injury in Rats with Glycerol-Induced Acute Kidney Injury , 2010, American Journal of Nephrology.

[49]  E. Homsi,et al.  Silymarin exacerbates p53-mediated tubular apoptosis in glycerol-induced acute kidney injury in rats , 2010, Renal failure.

[50]  G. Roh,et al.  N-acetylcysteine attenuates glycerol-induced acute kidney injury by regulating MAPKs and Bcl-2 family proteins. , 2010, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[51]  Shuang Huang,et al.  Heme oxygenase-1 induction contributes to renoprotection by G-CSF during rhabdomyolysis-associated acute kidney injury. , 2011, American journal of physiology. Renal physiology.

[52]  Hsi-Che Liu,et al.  Rasburicase improves hyperuricemia in patients with acute kidney injury secondary to rhabdomyolysis caused by ecstasy intoxication and exertional heat stroke , 2011, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

[53]  D. S. St. Clair,et al.  Manganese superoxide dismutase, MnSOD and its mimics. , 2012, Biochimica et biophysica acta.

[54]  R. Schnellmann,et al.  Recovery from Glycerol-Induced Acute Kidney Injury Is Accelerated by Suramin , 2012, Journal of Pharmacology and Experimental Therapeutics.

[55]  Benjamin R. Lee,et al.  Protective effects of reducing renal ischemia-reperfusion injury during renal hilar clamping: use of allopurinol as a nephroprotective agent. , 2013, Urology.

[56]  T. Erol,et al.  Efficacy of allopurinol pretreatment for prevention of contrast-induced nephropathy: a randomized controlled trial. , 2013, International journal of cardiology.

[57]  E. Gialamas,et al.  The role of allopurinol's timing in the ischemia reperfusion injury of small intestine , 2013, Journal of emergencies, trauma, and shock.

[58]  E. Ritz,et al.  Uric acid and chronic kidney disease: which is chasing which? , 2013, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[59]  Julio Pascual,et al.  Risk Factors for Acute Kidney Injury in Severe Rhabdomyolysis , 2013, PloS one.

[60]  A. Sudo,et al.  Protective effect of edaravone for tourniquet-induced ischemia-reperfusion injury on skeletal muscle in murine hindlimb , 2013, BMC Musculoskeletal Disorders.

[61]  J. Viña,et al.  Exercise and antioxidant supplements in the elderly , 2013 .

[62]  M. Irwin,et al.  N-Acetylcysteine and Allopurinol Confer Synergy in Attenuating Myocardial Ischemia Injury via Restoring HIF-1α/HO-1 Signaling in Diabetic Rats , 2013, PloS one.

[63]  E. Clementi,et al.  Allopurinol overuse in asymptomatic hyperuricemia: a teachable moment. , 2014, JAMA internal medicine.

[64]  K. Davies,et al.  Even free radicals should follow some rules: a guide to free radical research terminology and methodology. , 2015, Free radical biology & medicine.

[65]  J. Schanstra,et al.  Specific macrophage subtypes influence the progression of rhabdomyolysis-induced kidney injury. , 2015, Journal of the American Society of Nephrology : JASN.

[66]  S. Muto,et al.  Role of NLRP3 Inflammasomes for Rhabdomyolysis-induced Acute Kidney Injury , 2015, Scientific Reports.

[67]  E. Homsi,et al.  TNF-α-mediated cardiorenal injury after rhabdomyolysis in rats. , 2015, American journal of physiology. Renal physiology.

[68]  G. Lippi,et al.  Allopurinol prevents cardiac and skeletal muscle damage in professional soccer players , 2015, Scandinavian journal of medicine & science in sports.