Association of IL-4RA single nucleotide polymorphisms, HLA-DR and HLA-DQ in children with Alternaria-sensitive moderate-severe asthma

[1]  D. Denning,et al.  The effects of antifungal therapy on severe asthma with fungal sensitization and allergic bronchopulmonary aspergillosis , 2009, Respirology.

[2]  R. Slavin,et al.  HLA-DR, IL-4RA, and IL-10: Genetic Risk Factors in Allergic Bronchopulmonary Aspergillosis , 2008 .

[3]  J. Batra,et al.  Genetic association of acidic mammalian chitinase with atopic asthma and serum total IgE levels. , 2008, The Journal of allergy and clinical immunology.

[4]  Ying Sun,et al.  Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function. , 2008, The New England journal of medicine.

[5]  W. Busse,et al.  Severe asthma: lessons from the Severe Asthma Research Program. , 2007, The Journal of allergy and clinical immunology.

[6]  D. Denning,et al.  The link between fungi and severe asthma: a summary of the evidence , 2006, European Respiratory Journal.

[7]  A. Knutsen,et al.  IL-4 alpha chain receptor (IL-4Rα) polymorphisms in allergic bronchopulmonary sspergillosis , 2006, Clinical and Molecular Allergy.

[8]  D. Vercelli,et al.  IL-13 R130Q, a common variant associated with allergy and asthma, enhances effector mechanisms essential for human allergic inflammation. , 2005, The Journal of clinical investigation.

[9]  D. Denning,et al.  Mold sensitization is common amongst patients with severe asthma requiring multiple hospital admissions , 2005, BMC pulmonary medicine.

[10]  N. Keyhani,et al.  Allergens of the entomopathogenic fungus Beauveria bassiana , 2005, Clinical and molecular allergy : CMA.

[11]  A. Cantani,et al.  Epidemiology of alternaria alternata allergy: a prospective study in 6840 Italian asthmatic children. , 2004, European review for medical and pharmacological sciences.

[12]  G. K. Khurana Hershey,et al.  Functional effect of the R110Q IL13 genetic variant alone and in combination with IL4RA genetic variants. , 2004, The Journal of allergy and clinical immunology.

[13]  R. Bush,et al.  Alternaria-induced asthma. , 2004, The Journal of allergy and clinical immunology.

[14]  E. Lewiecki.  Clinical and Molecular Allergy , 2004 .

[15]  H. Burge,et al.  Fungal levels in the home and lower respiratory tract illnesses in the first year of life. , 2003, American journal of respiratory and critical care medicine.

[16]  Sabit Cakmak,et al.  The role of fungal spores in thunderstorm asthma. , 2003, Chest.

[17]  D. Corry,et al.  A Protease-Activated Pathway Underlying Th Cell Type 2 Activation and Allergic Lung Disease1 , 2002, The Journal of Immunology.

[18]  Bénédicte Leynaert,et al.  Sensitisation to airborne moulds and severity of asthma: cross sectional study from European Community respiratory health survey , 2002, BMJ : British Medical Journal.

[19]  Jonathan A. Bernstein,et al.  V75R576 IL-4 Receptor α Is Associated with Allergic Asthma and Enhanced IL-4 Receptor Function1 , 2002, The Journal of Immunology.

[20]  R. Chakraborty,et al.  V75R576 IL-4 receptor alpha is associated with allergic asthma and enhanced IL-4 receptor function. , 2002, Journal of immunology.

[21]  H. Kauffman,et al.  Prevalence of immunoglobulin E for fungi in atopic children , 2001, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[22]  G. Marks,et al.  Clinical importance of Alternaria exposure in children. , 2001, American journal of respiratory and critical care medicine.

[23]  R. Burnett,et al.  Influence of ambient fungal spores on emergency visits for asthma to a regional children's hospital. , 2000, American Journal of Respiratory and Critical Care Medicine.

[24]  E. Spitznagel,et al.  Evidence for the involvement of two different MHC class II regions in susceptibility or protection in allergic bronchopulmonary aspergillosis. , 2000, The Journal of allergy and clinical immunology.

[25]  H. Kauffman,et al.  Protease-dependent activation of epithelial cells by fungal allergens leads to morphologic changes and cytokine production. , 2000, The Journal of allergy and clinical immunology.

[26]  P. Black,et al.  Sensitivity to fungal allergens is a risk factor for life‐threatening asthma , 2000, Allergy.

[27]  A. Tsalenko,et al.  Variation in the interleukin 4-receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populations. , 2000, American journal of human genetics.

[28]  J. Bernstein,et al.  The R576 IL-4 receptor α allele correlates with asthma severity☆☆☆★ , 1999 .

[29]  S. Szefler,et al.  The relationships among environmental allergen sensitization, allergen exposure, pulmonary function, and bronchial hyperresponsiveness in the Childhood Asthma Management Program. , 1999, The Journal of allergy and clinical immunology.

[30]  J Bousquet,et al.  Is sensitization to Alternaria alternata a risk factor for severe asthma? A population-based study. , 1999, The Journal of allergy and clinical immunology.

[31]  Sparholt,et al.  The polymorphisms S503P and Q576R in the interleukin‐4 receptor α gene are associated with atopy and influence the signal transduction , 1999, Immunology.

[32]  M. Brown,et al.  Two subphenotypes of childhood asthma that differ in maternal and paternal influences on asthma risk. , 1999, American journal of respiratory and critical care medicine.

[33]  J. Bernstein,et al.  The R576 IL-4 receptor alpha allele correlates with asthma severity. , 1999, The Journal of allergy and clinical immunology.

[34]  T. Platts-Mills,et al.  Association of sensitization to Alternaria allergens with asthma among school-age children. , 1998, The Journal of allergy and clinical immunology.

[35]  R. Chapela,et al.  Analysis of the relationships between environmental factors (aeroallergens, air pollution, and weather) and asthma emergency admissions to a hospital in Mexico City , 1998, Allergy.

[36]  K. Deichmann,et al.  Linkage and allelic association of atopy and markers flanking the IL4‐receptor gene , 1998, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[37]  N. Hamasaki,et al.  Ile50Val variant of IL4R alpha upregulates IgE synthesis and associates with atopic asthma. , 1998, Nature genetics.

[38]  T. Chatila,et al.  The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor. , 1997, The New England journal of medicine.

[39]  P. Koutrakis,et al.  The effect of outdoor fungal spore concentrations on daily asthma severity. , 1997, Environmental health perspectives.

[40]  F. Martinez,et al.  Alternaria as a major allergen for asthma in children raised in a desert environment. , 1997, American journal of respiratory and critical care medicine.

[41]  A. Buist,et al.  Progression of asthma from childhood to adolescence , 1997 .

[42]  E. Kupek,et al.  Thunderstorm associated asthma: a detailed analysis of environmental factors , 1996, BMJ.

[43]  V. Persky,et al.  Effect of environmental molds on risk of death from asthma during the pollen season. , 1995, The Journal of allergy and clinical immunology.

[44]  S. Leeder,et al.  Importance of house dust mite and Alternaria allergens in childhood asthma: an epidemiological study in two climatic regions of Australia , 1993, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.